Mesane kanserinde lenf nodu pozitifliği ve patolojik evre ilişkisi

Objective & Hypothesis:Aim: The aim of our study was to review the relationship between patho- logical stage and lymph node metastasis in patients who underwent radical cystectomy for bladder cancer.

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Key Findings & Data:Material and Method: One hundred twenty- five patients who underwent radical cystectomy for bladder cancer between March 2005 and January 2012 were evaluated.

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Conclusion & Impact:Discussion: Although lymph node metastases seem to occur in patients with T2b or higher stages, it can be detected in patients with pT0 disease.

🔬Design:Review & Systematic Survey

📍Scope:2005 Verileri

⚙️Variables:Domain Parameters

Abstract

Aim: The aim of our study was to review the relationship between patho- logical stage and lymph node metastasis in patients who underwent radical cystectomy for bladder cancer. Material and Method: One hundred twenty- five patients who underwent radical cystectomy for bladder cancer between March 2005 and January 2012 were evaluated. Pathological evaluation and clinical features were retrospectively analyzed. Results: Mean age of 125 patients were 61.7 years (38-88) who underwent radical cystectomy. Seven (%5.6) patients were female and 118 (%94.4) were male. The median number of yielded lymph node (LN) was 16 (2-81) and median number of positive LN was 2 (1-29) who had metastatic LN. Twenty four patients had no tu- mour (pT0). Two patients had pT0 disease but had lymph node metastasis (pT0N1). One of them had neoadjuvant chemotherapy (NACT). Median lymph node density (LND) (positive LN/ total LN ratio) was 0.14(0,03-1). Patients’ pathological results are summarized on table 1. Discussion: Although lymph node metastases seem to occur in patients with T2b or higher stages, it can be detected in patients with pT0 disease.

Özet

Amaç: Radikal sistektomi yapılan hastalarda patolojik evre ve lenf nodu tu-tulumu arasındaki ilişkiyi inceledik. Gereç ve Yöntem: Mart 2005-Ocak 2012tarihleri arasında radikal sistektomi yapılan 125 hastanın klinik ve patolojik özellikleri retrospektif olarak incelendi. Bulgular: Radikal sistektomi yapılan 125 hastada ortalama yaş 61,7 (38-88) bulundu. Hastaların 7’si (%5,6) ka- dın, 118’i (% 94,4) erkekti. Çıkarılan lenf nodu(LN) sayısı ortanca 16 (2-81), LN tutulumu saptanan hastalarda pozitif LN sayısı ortanca 2 (1-29) saptan-dı. 24 (%19,2) hastada patolojik incelemede tümör saptanmadı (pT0). Hasta-ların ikisinde pT0 olmasına rağmen LN metastazı saptandı (pT0N1). Bu hastaların birinde neoadjuvan kemoterapi (NAKT) öyküsü vardı. Lenf nodu dan-sitesi (pozitif LN/toplam LN) ortanca:0,14 (0,03-1) bulundu. Patoloji bulguları Tablo 1’de özetlendi. Tartışma: Lenf nodu metastazı radikal sistektomi ya- pılan, pT2b ve daha ileri evre hastalıkta görülebilmekle birlikte pT0 hastalık- ta da lenf nodu metastazı saptanabilmektedir.

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Cite This Article

ÖZCAN, M. F., GÖK, B., AKBULUT, Z., ÖZDEMİR, A. T., ATMACA, A. F., CANDA, A. E. (2022). Mesane kanserinde lenf nodu pozitifliği ve patolojik evre ilişkisi. Journal of Clinical and Analytical Medicine, Cilt: 4 - Sayı: 5, 357–359. https://ajindex.com/articles/561315

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