SavedAdd your journal

Journals / Journal of Clinical and Analytical Medicine / 2014 / Cilt: 5 - Sayı: 5

Katarakt Cerrahisinde Perioperatif İntrakameral Kokteyl ile Topikal Tedavinin Karşılaştırılması

Perioperative Intracameral Cocktail Combination Vs Topical Treatment in Cataract Surgery

Harun ÇAKMAK
Tolga KOCATÜRK
Volkan DAYANIR
Sema DÜNDAR ORUÇ
Erkin KIR
Pages
369–373
Publication Date
2022-10-18
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

If there are more than or equal to 3 surgeries in an operatingday, then the use of cocktail is more economical compared to topical drops.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: To compare intracameral drug mixture cocktail with postoperative conventional topical antibiotic-steroid following phacoemulsification.
📊
Key Findings & Data:Materialand Method: This retrospective study comprised 60 eyes of 60 patients having phacoemulsification under topical anesthesia.
💡
Conclusion & Impact:If there are more than or equal to 3 surgeries in an operatingday, then the use of cocktail is more economical compared to topical drops.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: To compare intracameral drug mixture cocktail with postoperative conventional topical antibiotic-steroid following phacoemulsification. Materialand Method: This retrospective study comprised 60 eyes of 60 patients having phacoemulsification under topical anesthesia. The cocktail comprised ofvancomycin, ceftazidime, diclofenac, dexamethasone, triamcinolone acetonide and balanced salt solution. Best corrected visual acuity and intraocularpressure were measured preoperatively and at 1, 4, 8, 15 and 29th dayspostoperatively. Results: Best corrected visual acuity and intraocular pres- sure measurements did not show significant difference at any time points.More than or equal to 5mmHg rise in intraocular pressure was observed onpostoperative day 1 in 9(30%) eyes of Cocktail group and 3(10%) eyes ofTopical group. The difference was not significant (p=0,053).Discussion: Intracameral cocktail following phacoemulsification is as safe and effective astopical drops. If there are more than or equal to 3 surgeries in an operatingday, then the use of cocktail is more economical compared to topical drops.

Özet

Amaç: Fakoemulsifikasyon cerrahisi sonrası ön kamaraya verilen ilaç karışımı kokteyl ile konvansiyonel postoperatif topikal antibiyotik ve steroid kullanımının karşılaştırılması amaçlandı. Gereç ve Yöntem: Retrospektif olarak yapılan çalışmada topikal anestezi ile ameliyat edilen 60 hastanın 60 gözü dahil edildi. Kokteylin içinde vancomycin, ceftazidime, diclofenac, dexamethasone, triamcinolone acetonide ve dengeli tuz solüsyonu bulunuyordu. Ameliyatöncesi ve ameliyattan sonraki 1, 4, 8, 15 ve 29. günlerde tashihli görme keskinliği ve göz içi basıncı ölçülen hastalar çalışmaya dahil edildi. Bulgular: Yapılan takiplerde iki grup arasında tashihli görme keskinliği ve göz içi basıncıölçümleri arasında istatistiksel olarak anlamlı fark saptanmadı. Kokteyl grubunda postoperatif 1. günde 5mmHg veya daha fazla yükselme 9(%30) gözde, Topikal grubunda 3(%10) gözde görülmüştür. Ancak fark istatistiksel olarak anlamlı değildir (p=0,053). Tartışma: Fakoemulsifikasyon sonrası ön kamaraya verilen kokteyl, postoperatif topikal ilaç kullanımı kadar etkin ve güvenlidir. Aynı günde üç veya daha fazla ameliyat yapıldığında kokteyl kullanımı daha ekonomiktir.

🔖

Cite This Article

ÇAKMAK, H., KOCATÜRK, T., DAYANIR, V., ORUÇ, S. D., KIR, E. (2022). Katarakt Cerrahisinde Perioperatif İntrakameral Kokteyl ile Topikal Tedavinin Karşılaştırılması. Journal of Clinical and Analytical Medicine, Cilt: 5 - Sayı: 5, 369–373. https://ajindex.com/articles/561138

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Blodi FC. Cataract surgery. In: Albert DM, Edwards DD, editors. The history of ophthalmology. Cambridge, MA: Blackwell Scientific; 1996. p.165-77
  2. Apple DJ, Mamalis N, Loftfield K, Googe JM, Novak LC, Kavka-Van Norman D, et al. Complications of intraocular lenses: a historical and histopathological review. Surv Ophthalmol 1984;29(1):1-54
  3. Kelman C. Phaco-emulsification and aspiration. A new technique of cataract removal. A preliminary report. Am J Ophthalmol 1967;64(1):23-35
  4. Gimbel HV, Neuhann T. Development, advantages, and methods of the continu- ous circular capsulorrhexis technique. J Cataract Refract Surg 1990;16(1):31-7
  5. Allarakia L, Knoll RL, Lindstrom RL. Soft intraocular lenses. J Cataract Refract Surg 1987;13(6):607-20
  6. Leaming DV. Practice styles and preferences of ASCRS members-2003 survey. J Cataract Refract Surg 2004;30(4):892–900
  7. Libre PE, Della-Latta P, Chin NX. Intracameral antibiotic agents for endo- phthalmitis prophylaxis: a pharmacokinetic model. J Cataract Refract Surg 2003;29(9):1791-4
  8. Kodjikian L, Couprie J, Hachicha W, Timour Q, Devouassoux M, Builles N, et al. Experimental intracameral injection of vancomycin microparticles in rabbits. Invest Ophthalmol Vis Sci 2010;51(8):4125-32
  9. Maloof A, Saw V. Prophylactic intracameral vancomycin. J Cataract Refract Surg 2004;30(8):1610-1
  10. Gills JP, Rowsey JJ. Bacterial endophthalmitis prophylaxis for cataract surgery. Ophthalmology 2003;110(8):1668
  11. Gimbel HV, Sun R, DeBrof BM. Prophylactic intracameral antibiotics during cataract surgery: the incidence of endophthalmitis and corneal endothelial loss. Eur J Implant Refract Surg 1994;6:280-5
  12. Gills JP. Pharmacodynamics of cataract surgery. In: Gills JP, ed. Cataract Surgery: The State of the Art. Thorofare, NJ: Slack, Inc.;1998:19-26
  13. Ciulla TA, Starr MB, Masket S. Bacterial endophthalmitis prophylaxis for cataract surgery: an evidence-based update. Ophthalmology 2002;109(1):13-24
  14. Gills JP, Gills P. Effect of intracameral triamcinolone to control inflammation following cataract surgery. J Cataract Refract Surg 2005;31(8):1670-1
  15. Chylack LT Jr, Wolfe JK, Singer DM, Leske MC, Bullimore MA, Bailey IL, et al. The Lens Opacities Classification System III. The Longitudinal Study of Cataract Study Group. Arch Ophthalmol 1993;111(6):831-6
  16. Dayanir V, Sakarya R, Ozcura F, Kir E, Aktunç T, Ozkan BS, et al. Effect of corneal drying on central corneal thickness. J Glaucoma 2004;13(1):6–8