Journals / Journal of Clinical and Analytical Medicine / 2014 / Cilt: 5 - Sayı: 4

Antral Folikül Sayısının in Vitro Fertilizasyon Sonuçlari Üzerine Etkisi

Effect of Antral Follicle Count on in Vitro Fertilization Outcome

Pages
324–327
Publication Date
2022-10-18
DOI
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Results: Our findings indicated that there was not a statisticaldifference in number of total oocytes ( 11.03± 6.59 vs. 13.71± 5.38), embryos(5.7± 4.46 vs. 7.29± 5.05) and pregnancy rates ( 76.7% vs. 71.4%) betweengroups according to antral follicle size (AF ≤5mm vs.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: The aim of this study is to evaluate the effects of number and size ofantral follicles on ovarian reserve and subsequently in vitro fertilization (IVF)outcome.
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Key Findings & Data:Material and Method: 44 patients treated with IVF in the Infertility Clinic of Zeynep Kamil Women s and Children Disease Education andResearch Hospital (Istanbul, Turkey) were prospectively included in this study.On the third day of menstrual bleeding, transvaginal ultrasound was performed.
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Conclusion & Impact:Results: Our findings indicated that there was not a statisticaldifference in number of total oocytes ( 11.03± 6.59 vs. 13.71± 5.38), embryos(5.7± 4.46 vs. 7.29± 5.05) and pregnancy rates ( 76.7% vs. 71.4%) betweengroups according to antral follicle size (AF ≤5mm vs.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: The aim of this study is to evaluate the effects of number and size ofantral follicles on ovarian reserve and subsequently in vitro fertilization (IVF)outcome. Material and Method: 44 patients treated with IVF in the Infertility Clinic of Zeynep Kamil Women s and Children Disease Education andResearch Hospital (Istanbul, Turkey) were prospectively included in this study.On the third day of menstrual bleeding, transvaginal ultrasound was performed. Antral follicle count (AFC) and antral follicle (AF) size were recordedin these patients. Group I as AF > 5mm and Group II as AF ≤ 5mm were defined. The patients underwent controlled ovarian hyperstimulation with rec- FSH following. Results: Our findings indicated that there was not a statisticaldifference in number of total oocytes ( 11.03± 6.59 vs. 13.71± 5.38), embryos(5.7± 4.46 vs. 7.29± 5.05) and pregnancy rates ( 76.7% vs. 71.4%) betweengroups according to antral follicle size (AF ≤5mm vs. AF >5 mm) . Under thearea of ROC curve estimations for ovarian response revealed that antral follicle (AF) >5 mm had the largest area 0.675±0.083 (0.517-0.808). Discussion:There might be an association between AF that is larger than 5 mm in sizeand number of retrieved mature oocytes. Since AFC, is a routine screeningtest in any IVF center, we believe paying closer attention to the measurementof AFC that are larger than 5 mm in size might help clinicians to achievemore successful outcomes in terms of on embryo quality and pregnancy out- come in women undergoing an in vitro fertilization.

Özet

Amaç: Bu calışmada antral folikül sayısı ve boyutunun over rezervi ile birlikte in vitro fertilizasyon sonuçlari üzerine etkisini incelemek istedik. Gereç veYöntem: Zeynep Kamil Egitim ve Araştırma Hastanesi tüp bebek ünitesinde tedaviye başlanan 44 hasta prospektif olarak incelendi. Menstruasyonun3. Gününde transvaginal ultrason uygulandı. Antral folikül sayıları ve boyutları kaydedildi. Antral folikül boyutuna göre hastalar iki gruba ayrıldı. Grup 1AF >5mm ve Grup IIAF ≤5mm olarak belirlendi. Kontrollü over stimulasyonuiçin rec-FSH kullanıldı. Baslangıç dozu hastanın yaşı, over rezervi veya önceki tedaviye olan yanıtına göre belirlendi. Bulgular: Çalışmamızda antral folikül boyutuna göre (AF >5mm ve AF ≤5mm) gruplar arasında total oosit sayısı( 11.03± 6.59 vs. 13.71± 5.38), embriyo (5.7± 4.46 vs. 7.29± 5.05) ve gebelikoranları arasında ( 76.7% vs. 71.4%) istatiksel olarak bir fark saptanmamıştır. Over cevabı açısında receiver operating eğrisi analizi yapıldığında eğri altında kalan alan AF > 5 mm olanlarda 0.675±0.083 (0.517-0.808) olarak tespit edildi. Tartışma: Boyutu 5 mm üzerindeki antral folikul sayısı ile elde edilenmatür oosit sayısı arasında ilişki olabilir. Antral folikül sayısının tayini IVF öncesi rutin bir test olması nedeniyle , özellikle 5 mm üzerindeki antral foliküllerinin sayısının önceden belirlenmesi klinisyenin embriyo kalitesi ve gebelik anlamında daha başarılı sonuçlar elde etmesine yardımcı olabilir.

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Cite This Article

EREN, S., KUTLU, T., BAYKAL, B., BATU, P., BASTU, E., ABALI, R., ÇELİK, C. (2022). Antral Folikül Sayısının in Vitro Fertilizasyon Sonuçlari Üzerine Etkisi. Journal of Clinical and Analytical Medicine, Cilt: 5 - Sayı: 4, 324–327. https://ajindex.com/articles/561130

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