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Journals / Journal of Clinical and Analytical Medicine / 2015 / Cilt: 6 - Sayı: 3

Bronşiyal astımlı çocuklarda chlamydia pneumoniae ve mycoplasma pneumoniae seropozitifiği

Seropositivity for chlamydia pneumoniae and mycoplasma pneumoniae in asthmatic children

Ali GÜNEŞ
Servet YEL
M. Fuat GÜRKAN
Gülseren BİLEN
Murat TUTANÇ
Çapan KONCA
Pages
353–357
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The results obtained revealthe efect of both microorganisms on the etiopathogenesis of the bronchialasthma and the increased number of asthma attacks.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Acute respiratory tract infections may trigger acute asthma attacks and maybe held responsible for etiopathogenesis in children with asthma.
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Key Findings & Data:IgM and IgG seroprevalence was investigated in 66 children patients with bronchial asthma (between the ages of3 and 14) for CP and Mycoplasma pneumoniae.
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Conclusion & Impact:The results obtained revealthe efect of both microorganisms on the etiopathogenesis of the bronchialasthma and the increased number of asthma attacks.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Acute respiratory tract infections may trigger acute asthma attacks and maybe held responsible for etiopathogenesis in children with asthma. Althoughbacterial infections attract a limited amount of attention, recently Chlamydiapneumoniae (CP) and Mycoplasma pneumoniae (MP), in particular, are reported to be the possible factors. IgM and IgG seroprevalence was investigated in 66 children patients with bronchial asthma (between the ages of3 and 14) for CP and Mycoplasma pneumoniae. In a total of 66 cases, 18(27.2%) patients were detected with IgG positivity for CP whereas 27 ofthem (40.9%) were detected with IgG positivity for MP. IgG positivity wasdetermined in 6 patients (13.0%) in the control group for CP, and in 6 patients(10.8%) in the control group for MP. The rate of the asthma patients withIgG seropositivity for MP was 4 times higher than that of the control group.It was seen that IgG antibody seropositivity for CP was higher in those withmore frequent attacks. No such diference was observed in terms of IgGantibody seropositivity for M. pneumoniae. There are many studies indicating that CP and MP infections take an importance place in the etiology ofbronchial asthma and asthma attacks in children. The results obtained revealthe efect of both microorganisms on the etiopathogenesis of the bronchialasthma and the increased number of asthma attacks.

Özet

Akut solunum yolu enfeksiyonları astımlı çocuk hastalarda akut astım atağını tetikleyebilir ve etyopatogenezde sorumlu tutulabilir. Bakteriyel enfeksiyonlar daha az dikkati çekmekle beraber son zamanlarda özellikle Chlamydiapneumoniae (CP) ve Mycoplasma pneumoniae (MP) olası etken olarak bildirilmektedir. Bronşiyal astımlı (3-14 yaş arası) 66 çocuk hastada CP ve Mycopasma pneumoniae IgM ve IgG seroprevalansı araştırıldı. Toplam 66 olgunun18inde (%27.2) CP IgG, 27sinde (%40.9) MP IgG pozitifiği saptandı. Kontrol grubunun 6sında (%13.0) CP IgG, 6sında (%10.8) MP IgG pozitifiği saptandı. Astım hastalarında MP IgG seropozitifiği olanların oranı kontrol grubunun 4 katı fazlaydı. Daha sık atak geçirenlerde CP IgG antikoru seropozitifiğinin daha fazla olduğu görüldü. M. pneumaniae IgG antikoru seropozitifiği açısından böyle bir farklılığa rastlanmadı. CP ve MP enfeksiyonlarının çocuklarda bronşiyal astım ve astım atağı etyolojisinde önemli yer tuttuğunadair pek çok çalışma vardır. Sonuçlarımız her iki mikroorganizmanın bronşiyal astım etyopatogenezinde ve astım atağı sayısının artışında etkili olduğunu ortaya koymaktadır.

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Cite This Article

GÜNEŞ, A., YEL, S., GÜRKAN, M. F., BİLEN, G., TUTANÇ, M., KONCA, Ç. (2022). Bronşiyal astımlı çocuklarda chlamydia pneumoniae ve mycoplasma pneumoniae seropozitifiği. Journal of Clinical and Analytical Medicine, Cilt: 6 - Sayı: 3, 353–357. https://ajindex.com/articles/561059

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