OBJECTIVE: To investigate the predictive value of HOS test and semen parameters in patients with total fertilization failure during IVF.STUDY DESIGN: In Istanbul University Cerrahpasa School of Medicine IVF Unit, the HOS test and semen parameters of 52 patients with total fertilization failure on at least two occasions during IVF cycles were compared with the results of 20 men who had successful fertilization with IVF and at least one offspring.RESULT(s): The HOS test results in the total fertilization failure and control groups were 34±27% and 56±23%, respectively (p
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Objective & Hypothesis:OBJECTIVE: To investigate the predictive value of HOS test and semen parameters in patients with total fertilization failure during IVF.STUDY DESIGN: In Istanbul University Cerrahpasa School of Medicine IVF Unit, the HOS test and semen parameters of 52 patients with total fertilization failure on at least two occasions during IVF cycles were compared with the results of 20 men who had successful fertilization with IVF and at least one offspring.RESULT(s): The HOS test results in the total fertilization failure and control groups were 34±27% and 56±23%, respectively (p
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Key Findings & Data:OBJECTIVE: To investigate the predictive value of HOS test and semen parameters in patients with total fertilization failure during IVF.STUDY DESIGN: In Istanbul University Cerrahpasa School of Medicine IVF Unit, the HOS test and semen parameters of 52 patients with total fertilization failure on at least two occasions during IVF cycles were compared with the results of 20 men who had successful fertilization with IVF and at least one offspring.RESULT(s): The HOS test results in the total fertilization failure and control groups were 34±27% and 56±23%, respectively (p
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Conclusion & Impact:OBJECTIVE: To investigate the predictive value of HOS test and semen parameters in patients with total fertilization failure during IVF.STUDY DESIGN: In Istanbul University Cerrahpasa School of Medicine IVF Unit, the HOS test and semen parameters of 52 patients with total fertilization failure on at least two occasions during IVF cycles were compared with the results of 20 men who had successful fertilization with IVF and at least one offspring.RESULT(s): The HOS test results in the total fertilization failure and control groups were 34±27% and 56±23%, respectively (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
OBJECTIVE: To investigate the predictive value of HOS test and semen parameters in patients with total fertilization failure during IVF.STUDY DESIGN: In Istanbul University Cerrahpasa School of Medicine IVF Unit, the HOS test and semen parameters of 52 patients with total fertilization failure on at least two occasions during IVF cycles were compared with the results of 20 men who had successful fertilization with IVF and at least one offspring.RESULT(s): The HOS test results in the total fertilization failure and control groups were 34±27% and 56±23%, respectively (p
Özet
AMAÇ: İn vitro fertilizasyonda total fertilizasyon başarısızlığı olan hastalarda, spermiogramın ve hipoosmotik şişme testinin (HOST ) fertilizasyon başarısızlığını belirlemedeki değerinin incelenmesi.MATERYAL ve METOD: Cerrahpaşa Tıp Fakültesi Kadın Hastalıkları ve Doğum Kliniği Tüp Bebek Ünitesi'nde en az iki kez IVF'de fertilizasyon başarısızlığı olan 52 IVF olgusunun sperm parametreleri ve HOST sonuçları, IVF yöntemiyle başarılı fertilizasyonu ve çocuğu olan 20 kişilik kontrol grubunun değerleri ile karşılaştırıldı.BULGULAR: Başarısız fertilizasyon grubunda ortalama HOST değeri % 34.5±27'ken, kontrol grubunda aynı değer % 56±23'dü (p
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Cite This Article
ÖCAL, P., ÇEPNİ, İ., ŞENOL, H., ELİBOL, F., YALDIR, F., ALBAYRAK, M. (2022). The predictive value of hypoosmotic swelling (HOS) test and semen parameters for determining fertilization failure in IVF. Jinekoloji ve Obstetrik Derg., Cilt: 18 - Sayı: 2, 97–100. https://ajindex.com/articles/559104
References (13)
Hauser R, Yavetz H, Paz GF, Hamonnai ZT, Amit A, Lessing JB, Payser MR, Yogev L: The predictive fertilization value of the hypoosmotic swelling test (HOST) for fresh and cry- opreserved sperm.1 Assist Reprod Genet 70:265, 1992
Kiefer D, Check JH, Katsoff D: The value of motile density, strict morphology, and the hypoosmotic swelling test in invitro fertilization-embryo transfer. Arch Androl 37:57, 1996
Bilijan MM, Buckett WM, Taylor CT, Luckas M, Aird I, Kingsland CR, Lewis-Jones DI: Effect of hypo-osmotic swelling test on fertilization rate and pregnancy outcome in in vitro fertilization cycles. Fertil Steril 66:412, 1996
A very S, Bolton VN, Mason BA: An evaluation of the hypo- osmotic sperm swelling test as a predictor of fertilizing capacity invitro. Int J Androl 13:93, 1990
Check JH, Katsoff D, Check ML, Choe JK, Swenson K: İn vitro fertilization with intracytoplasmic sperm injection in an effective therapy for male factor infertility related to subnormal hypo-osmotic swelling test scores. J Androl 22:261, 2001
Jeyendran RS, Van der Ven H, Perez-Palaez M, Crabo Bg, Zaneveld LJD: Development of an assay to asses the functional integrity of human sperm membrane and its relationship to the other semen characteristics. J Reprod Fertil 70:219-28, 1984
World Health Organization: WHO Laboratory Manuel for the examination of human semen and sperm-cervical mucus interaction, ed 3, Cambridge UK. Cambridge University Press 1992
İrez T, Akkuş E, Fıçıcıoğlu C, Çepni İ, Özkara H, Aksu F: Fertil ve infertil erkek sperminde hipoosmotik şişme testi alt guruplarının değerlendirilmesi. İstanbul Jinokol ve Obstet 1:75, 1997
Mordel N, Mor-Yosef S, Margolioth EJ, Shemesh A, Samueloff A, shenker JG: The human sperm hypo osmotic sweeling test: its practical application and suggestionfor improvoment. İnt J Fertil 34:355, 1989
Check JH, Stumpo L, Lurie D, Benfer K, Callan C: Acomperative prospective study using matched samples to deter mine the influence of subnormal hypo-osmotic test scores on subsequent fertilization and pregnency rates fallowing in-vitro fertilization. Hum Reprod 10:1197, 1995
Abu-Musa A, Takahashi K, Kitao M: Correlation between postswim-up hypoosmotic sweeling test and in vitro fertilization results. İnt J Fertil 38:113, 1993