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Journals / Jinekoloji ve Obstetrik Derg. / 2004 / Cilt: 18 - Sayı: 4

The relationship between lipoprotein (a) and the severity of preeclampsia

Preeklampsi patogenezi ve şiddetinde serum lipoprotein (a) düzeylerinin geçerliliği

Şükrü ÖZBÖRÜ
Erdal MALATYALIOĞLU
Mehmet Bilge ÇETİNKAYA
Arif KÖKÇÜ
Tayfun ALPER
Pages
221–224
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There were not any significant correlation between the serum lipoprotein (a) levels and any other parameter studied the preeclamptic cases.CONCLUSION: This study revealed that serum lipoprotein (a) level did not play an important role in the diagnosis and severity of the preeclampsia.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: The aim of this study is to investigate the serum lipoprotein (a) levels in normal pregnancy and preeclampsia and to investigate the relationship between lipoprotein (a) and the severity of preeclampsia.STUDY DESIGN: The study group comprised of 80 pregnant women with preeclampsia (34 mild preeclamptic, 36 severe preeclamptic and 10 eclamptic cases) and a total of 80 healthy pregnant controls who attended the Obstetrics and Gynecology department.
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Key Findings & Data:In statistical analysis Mann Whitney U test was used.RESULTS: The serum lipoprotein (a) levels (Mean±SEM) in the mild preclampsia group and its control were (19.8±2.3-19.2±2.1 mg/dl), the severe preeclampsia group and its control were (26.7±2.9-21.2±2.5 mg/dl), the eclampsia group and its control were (20.9±5.1-16.8±6.3 mg/dl).
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Conclusion & Impact:There were not any significant correlation between the serum lipoprotein (a) levels and any other parameter studied the preeclamptic cases.CONCLUSION: This study revealed that serum lipoprotein (a) level did not play an important role in the diagnosis and severity of the preeclampsia.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: The aim of this study is to investigate the serum lipoprotein (a) levels in normal pregnancy and preeclampsia and to investigate the relationship between lipoprotein (a) and the severity of preeclampsia.STUDY DESIGN: The study group comprised of 80 pregnant women with preeclampsia (34 mild preeclamptic, 36 severe preeclamptic and 10 eclamptic cases) and a total of 80 healthy pregnant controls who attended the Obstetrics and Gynecology department. The control case with a similar gestational age was selected for each study case among the healthy pregnant women. Serum lipoprotein (a) levels were determined by the nephalometric method. In statistical analysis Mann Whitney U test was used.RESULTS: The serum lipoprotein (a) levels (Mean±SEM) in the mild preclampsia group and its control were (19.8±2.3-19.2±2.1 mg/dl), the severe preeclampsia group and its control were (26.7±2.9-21.2±2.5 mg/dl), the eclampsia group and its control were (20.9±5.1-16.8±6.3 mg/dl). None of the study groups had significantly different serum lipoprotein(a) levels when compared to their control groups respectively (p>0.05). There were not any significant correlation between the serum lipoprotein (a) levels and any other parameter studied the preeclamptic cases.CONCLUSION: This study revealed that serum lipoprotein (a) level did not play an important role in the diagnosis and severity of the preeclampsia.

Özet

AMAÇ: Serum lipoprotein (a) düzeylerinin preeklamptik ve normal gebelerdeki düzeyleri ve lipoprotein (a) düzeyi ile preeklampsi şiddeti arasındaki ilişkinin araştırılmasıdır.MATERYAL ve METOD: Bu çalışma, 80 preeklampsili (34 hafif preeklampsi, 36 şiddetli preeklampsi, 10 eklampsi) gebe olgu ve her hasta grubuna uygun olacak sayıda toplam 80 sağlıklı gebeden oluşan kontrol grubu üzerinde yapıldı. Lipoprotein (a) serumda nefalometri yöntemiyle çalışıldı. İstatistiksel hesaplamalarda Mann Whitney U test kullanıldı.BULGULAR: Serum lipoprotein (a) düzeyleri (ortalama±SS) hafif preeklampsi ve kontrol grubunda (19.8±2.3-19.2±2.1 mg/dl), şiddetli preeklampsi ve kontrol grubunda (26.7±2.9-21.2±2.5 mg/dl), eklampsi ve kontrol grubunda ise (20.9±5.1-16.8±6.3 mg/dl) olarak bulundu. Hafif preeklampsi, şiddetli preeklampsi ve eklampsili olgularda kontrol gruplarına göre serum lipoprotein (a) düzeyleri arasında istatistiksel olarak anlamlı fark yoktu (p>0.05). Preeklampsili olgularda serum lipoprotein (a) düzeyleri ile çalışmada kullanılan diğer parametreler arasında anlamlı korelasyon saptanamadı.SONUÇ: Bu çalışma serum lipoprotein(a) düzeyinin, preeklampsi tanısında ve şiddetinde önemli bir rol oynamadığını göstermektedir.

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Cite This Article

ÖZBÖRÜ, Ş., MALATYALIOĞLU, E., ÇETİNKAYA, M. B., KÖKÇÜ, A., ALPER, T. (2022). The relationship between lipoprotein (a) and the severity of preeclampsia. Jinekoloji ve Obstetrik Derg., Cilt: 18 - Sayı: 4, 221–224. https://ajindex.com/articles/559096

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