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Journals / Jinekoloji ve Obstetrik Derg. / 2004 / Cilt: 18 - Sayı: 3

The relationship of pregnancy complications and AFP, HCG and estriol level detected in maternal serum

Maternal kanda AFP, HCG ve ankonjuge östriol düzeylerinin gebelik komplikasyonları ile ilişkisi

Cevval ULMAN
Selman LAÇİN
Yıldız UYAR
Bülbül Yeşim BAYBUR
Tayfun Hasan ÖZÇAKIR
Fatma TANELİ
Tuğrul ÇELİK
Pages
140–144
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The patients with high AFP levels (>2 MoM), high HCG levels (>2 MoM), low AFP levels (2 MoM), 13 patients with low AFP (

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: The aim of the study was to determine the relationship of intrauterine death, prematurity, intrauterine growth retardation, surmaturation and preeclampsia with high and low AFP, high HCG and low estriol levels detected in maternal serum.STUDY DESING: 1020 patients who had undergone tripple test during pregnancy for intrauterine death, prematurity, surmaturation, intrauterine growth retardation and preeclampsia rates between 1999-2003 at Celal Bayar University Hospital were determined.
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Key Findings & Data:OBJECTIVE: The aim of the study was to determine the relationship of intrauterine death, prematurity, intrauterine growth retardation, surmaturation and preeclampsia with high and low AFP, high HCG and low estriol levels detected in maternal serum.STUDY DESING: 1020 patients who had undergone tripple test during pregnancy for intrauterine death, prematurity, surmaturation, intrauterine growth retardation and preeclampsia rates between 1999-2003 at Celal Bayar University Hospital were determined.
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Conclusion & Impact:The patients with high AFP levels (>2 MoM), high HCG levels (>2 MoM), low AFP levels (2 MoM), 13 patients with low AFP (
🔬Design:Research Article
📍Scope:2003 Verileri
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: The aim of the study was to determine the relationship of intrauterine death, prematurity, intrauterine growth retardation, surmaturation and preeclampsia with high and low AFP, high HCG and low estriol levels detected in maternal serum.STUDY DESING: 1020 patients who had undergone tripple test during pregnancy for intrauterine death, prematurity, surmaturation, intrauterine growth retardation and preeclampsia rates between 1999-2003 at Celal Bayar University Hospital were determined. The patients with high AFP levels (>2 MoM), high HCG levels (>2 MoM), low AFP levels (2 MoM), 13 patients with low AFP (

Özet

AMAÇ: Bu çalışmada Manisa ili ve çevresindeki gebe popülasyonunda maternal kanda yüksek AFP, yüksek HCG, düşük AFP ve düşük ankonjuge östriol değerleri ile intrauterin ölüm, prematürite, intrauterin gelişme geriliği, sürmatürite ve preeklampsi arasındaki ilişkiyi araştırmayı amaçladık.MATERYAL ve METOD: Celal Bayar Üniversitesi Tıp Fakültesi Kadın Hastalıkları ve Doğum Kliniği'nde 1999-2003 yılları arasında üçlü tarama testi yapılan 1020 hastanın gebelik sırasındaki in utero ölüm, prematürite, sürmatürite, intrauterin gelişme geriliği ve preeklampsi oranlarını telefonla ve hastane kayıtlarını taramak yoluyla inceledik. Maternal kanda yüksek AFP (>2 MoM), yüksek HCG (>2 MoM), düşük AFP (2 MoM), 13'ünde düşük AFP (

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Cite This Article

ULMAN, C., LAÇİN, S., UYAR, Y., BAYBUR, B. Y., ÖZÇAKIR, T. H., TANELİ, F., ÇELİK, T. (2022). The relationship of pregnancy complications and AFP, HCG and estriol level detected in maternal serum. Jinekoloji ve Obstetrik Derg., Cilt: 18 - Sayı: 3, 140–144. https://ajindex.com/articles/559089

References (15)

  1. Wald NJ, Cuckle HS, Densem JW, Nanchahal K, Royston P, Chard T: Maternal serum screening for Down's syndrome in early pregnancy. BMJ 297:883-7, 1988
  2. Pergament E, Stein AK, Fiddler M, Clio NH, Kupfermine MJ: Adverse pregnancy outcome after a false positive screen for down syndrome using multiple markers. Obstet Gynecol 86:255-58, 1995
  3. Chapman SJ, Brumfiled CG, Wenstrom Kd, Dubard MB: Pregnancy outcomes following false positive multiple marker screening tests. Am J Perinatol 14:475-8, 1997
  4. Dungan JS, Schulman LP, Philips OP, Simpson,IL, Meyer NL, Grevengood C, Elias S: Pozitive serum screening for fetal Down Syndrome does not predict adverse pregnancy outcome in absence of fetal aneuploidi. J Soc Gynecol Invest 1:55-8, 1994
  5. Wald N, Cuckle H, Stirrat Gin, Bennet MJ, Turnbull AC: Maternal serum alpha-feto protein and low birth-weight. Lancet 268-70, 1977
  6. Brock D.IH, Barron L, Duncan P, Scrimgeour,JB, Watt M: Significance of elevated mid-trimester maternal plasma alpha- fetoprotein values. Lancet 1281-2, 1979
  7. Jauniaux E, Gulbis B, Tunkel S, Ramsay B, Campbell S, Meuris S: Maternal serum testing for alpha-fetoprotein and human chorionic gonadotropin in high-risk pregnancies. Prenat Diag 16:1129-35, 1996
  8. Morssink LP, Kornman LH, Beekhuris JR, De Wolf BTHM, Mantingh A: Abnormal levels of maternal serum human chorionic gonadotropin and alpha-feloprotein in the sec ond trimester: relation to fetal weight and preterm delivery, Prenat Diagn 1041-46, 1995
  9. Mimic TS, Johnson P: Second trimester maternal serum B- human chorionic gonadotropin and pregnancy outcome. Br J Obstet Gynecol 106:598-600, 1999
  10. Liepmann RE, Williams MA, Zingheim R, Hickok DE: Am J Obstet Gynecol 168:1852-7, 1993
  11. Walker JJ, Dekker GA: Te etiology and pathophysiology of hypertension in pregnancy. In: Walker JJ. Gant NF. Hypertension in Pregnancy. London Chapmann and Hall Medical 39, 1997
  12. Stamilio DM, Sehdev HM, Morgan MA, Propert K, Macones GA: Can antenatal clinical and biochemical markers predict the development of severe preeclampsia? Am J Obstet Gynecol 182:589-94,2000
  13. Masse J, Giguere Y, Kharfi A, Girouard J, Forest JC: Pathophysiology and maternal biologic markers of preeclampsia. Endocrine 19:113-25,2002
  14. Klockenbusch W, Steinhard J: Early detection of pre eclampsia within the scope of prenatal care. Zentralbl Gynakol 121:617-22, 1999
  15. Hung TH, Shau WY, Hsieh CC, Chiu TH, Hsu JJ, Hsieh TT: Risk factors for placenta accreta. Obste