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Journals / İzmir Tepecik Eğitim Hastanesi Dergisi / 2019 / Cilt: 29 - Sayı: 2

Different Forms of Lidocaine Administration During Transrectal Ultrasound Guided Prostate Biopsy: Results of a Randomized Clinical Trial

Transrektal Ultrason Eşliğinde Prostat Biyopsisinde Farklı Lidokain Formlarının Uygulanması: Randomize Kontrollü Klinik Çalışma Sonuçları

Osman Raif KARABACAK
Erdem KISA
Pages
134–139
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

LS was found to reduce VAS scores statistically significantly more than the other three methods w(p=0.025

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: This study aims to compare the spray form of lidocaine (LS), which is a local anesthetic agent, to its otherformulations including lidocaine cream (LC) and lidocaine gel (LG) by administering a visual analogue scale (VAS)to obtain post-transrectal ultrasound- guided biopsy (TRUSG-Bx) pain scores.Methods: Patients who presented to our clinic with lower urinary tract symptoms and/or had PSA levels requestedfor assessment purposes, or had PSA levels exceeding 2.5 ng/ml and/or suspicious findings in their rectal examination between 2014 May-2015 February were included in the study.
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Key Findings & Data:The records of 175 patients were randomizedto 4 groups.
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Conclusion & Impact:LS was found to reduce VAS scores statistically significantly more than the other three methods w(p=0.025
🔬Design:Research Article
📍Scope:2014 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: This study aims to compare the spray form of lidocaine (LS), which is a local anesthetic agent, to its otherformulations including lidocaine cream (LC) and lidocaine gel (LG) by administering a visual analogue scale (VAS)to obtain post-transrectal ultrasound- guided biopsy (TRUSG-Bx) pain scores.Methods: Patients who presented to our clinic with lower urinary tract symptoms and/or had PSA levels requestedfor assessment purposes, or had PSA levels exceeding 2.5 ng/ml and/or suspicious findings in their rectal examination between 2014 May-2015 February were included in the study. The records of 175 patients were randomizedto 4 groups. Group 1: Periprostatic nerve block (PPNB) 5 ml lidocaine injection to both neuromuscular bundles),Group 2: PPNB accompanied by 5g 5% LC applied to the perianal mucosa 5 min before the procedure, Group 3:PPNB accompanied by perianal-intrarectal 5 ml 2% LG 10 min before the procedure, Group 4: PPNB accompaniedby 5 doses of LS (10 mg/100 ml) administered perianally 2 min before the procedure. The pain felt by the patientsafter 30 min from the operation was evaluated using a VAS.Results: Mean VAS scores of the groups were estimated as follows: Group 1: 13.34±1.3, Group 2: 2.81±1.9; Group3: 3.52±1.9, and Group 4: 2.56±1.2. The lowest, and highest mean VAS scores were detected in Groups 4, and 3,respectively. LS was found to reduce VAS scores statistically significantly more than the other three methods w(p=0.025

Özet

Amaç: Bu çalışmanın amacı, transrektal ultrason (TRUS-bx) eşliğinde prostat biyopsisi öncesi uygulanan lidokainin sprey ile diğer jel ve krem formlarının, TRUS-bx sonrası ortaya çıkan ağrıya olan etkilerini karşılaştırmayı amaçlamaktadır. Yöntem: 2014 Mayıs-2015 Şubat arasında, PSA düzeyleri 2,5 üstünde olan ve/veya rektal muayenede şüpheli bulgusu olan toplam 175 hasta çalışmaya dahil edildi. Hastalar 4 gruba randomize edildi. Perinöral blokaj (PNB, her iki bölgeye 5 ml lidokain) (Grup 1; n=40), işlemden 5. dk. önce perianal mucosaya 5% 5 g lidokain krem (LK)+PNB (Grup 2; n=46), işlemden 10 dk. önce perianal-intrarektal 5 ml %2 lidokain jel (LJ) +PNB (Grup 3; n=50), işlemden 2 dk. önce perianal (valsalva manevrasıyla prolabe olan mucosaya) 5 doz lidokain sprey (LS) (10 mg/100 ml) + PNB (Grup 4; n=39) uygulandı. İşlemden 30 dk. sonra hastaların duydukları ağrı, vizüel analog skala (VAS) ile değerlendirildi. Bulgular: VAS skoru ortalamaları grup 1 PNB’de 3,3±1,3, grup 2 PNB+ LK’de 2,8±1,9, grup 3 PNB+ LJ’de 3,5±1,9 ve grup 4 PNB+LS’de 2,5±1,2 olarak hesaplandı. Ortalama VAS skoru en düşük grup 4, en yüksek grup 3 idi. PNB’ye LS veya LK eklenmesi, VAS ortalamalarını düşürmesine rağmen, LS’nin, diğer 3 yönteme göre ağrı VAS skorunu istatistiksel olarak anlamlı azalttığı gözlemlenmiştir (p=0,025

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Cite This Article

KARABACAK, O. R., KISA, E. (2022). Different Forms of Lidocaine Administration During Transrectal Ultrasound Guided Prostate Biopsy: Results of a Randomized Clinical Trial. İzmir Tepecik Eğitim Hastanesi Dergisi, Cilt: 29 - Sayı: 2, 134–139. https://ajindex.com/articles/558100

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