Journals / İzmir Tepecik Eğitim Hastanesi Dergisi / 2021 / Cilt: 31 - Sayı: 3

Choroidal Thickness in Children with Congenital Heart Disease Measured by Spectral Domain Optical Coherence Tomography§

Doğuştan Kalp Hastalıklı Çocuklarda Optik Koherens Tomografi ile Koroid Kalınlığının Değerlendirilmesi

Pages
338–343
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The reason may be medical and surgical treatment of hypoxia, erythrocytosis and volume overload in CHD patients.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The main reason for complications in congenital heart diseases (CHD) is decreased blood oxygen saturation and polycythemia which are typical for cyanosis.
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Key Findings & Data:Methods: This prospective study compared 30 CHD and 30 healthy control children.
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Conclusion & Impact:The reason may be medical and surgical treatment of hypoxia, erythrocytosis and volume overload in CHD patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The main reason for complications in congenital heart diseases (CHD) is decreased blood oxygen saturation and polycythemia which are typical for cyanosis. These parameters may promote the damage of the retina because haemodynamic regulation is essential for the structural and functional integrity of the macular subfields. The aim of this study was to evaluate choroidal thickness (CT) measurements in children with CHD using spectral domain optical coherence tomography (OCT). Methods: This prospective study compared 30 CHD and 30 healthy control children. CT was examined with spectralis spectral-domain OCT (Retinascan RS-3000; Nidek). CT was obtained at the subfovea, 500 μm and 1000 μm nasal to the fovea (N500, N1000) and 500 μm and 1000 μm temporal to the fovea (T500, T1000). Only the right eye values were used for statistical comparisons between the groups. The domain cardiac lesions were divided physiologically into two categories: volume overload and cyanotic. Results: Mean age was 11.0±3.5 years in CHD childrens and 10.9±3.6 years in the control group (p=0.971). Children with CHD had no statistically significant CT measurements compared with healthy controls (p>0.05). Conclusion: Although in high haematocrit, low oxygen saturation or the presence of the volume overload in the history of CHD patients, our data suggests that patients with CHD show normal CT. The reason may be medical and surgical treatment of hypoxia, erythrocytosis and volume overload in CHD patients.

Özet

Amaç: Spektral-domain optik koherens tomografi (SDOKT) kullanarak doğuştan kalp hastalıklı (DKH) çocuklarda koroid kalınlığının değerlendirilmesi amaçlanmıştır. Doğuştan kalp hastalığında komplikasyonların başlıca nedeni, siyanoz için tipik olan düşük arteriyel oksijen saturasyonu ve polisitemidir. Bu parametreler retinal hasarı artırabilir, çünkü hemodinamik regülasyon makuler alt alanların yapısal ve işlevsel bütünlüğü için gereklidir. Yöntem: Bu prospektif çalışmada 30 DKH’lı ve 30 sağlıklı çocuk karşılaştırıldı. Koroid kalınlığı SDOKT ile incelendi (Retinascan RS-3000; Nidek). Koroidal kalınlık; subfovea, 500 μm ve 1000 μm nazal fovea (N500, N1000) ve 500 μm ve 1000 μm temporal foveal alan (T500, T1000) ölçülerek elde edildi. Gruplar arasındaki istatistiksel karşılaştırmalar için sadece sağ göz değerleri kullanıldı. Kardiyak patolojiler fizyolojik olarak volüm yükü yapan ve siyanotik olarak iki kategoriye ayrıldı. Bulgular: DKH’li çocuklarda yaş ortalaması 11.0±3.5 yıl, kontrol grubunda 10.9±3.6 yıl idi (p = 0.971). DKH’li çocuklar, sağlıklı kontrollerle karşılaştırıldığında istatistiksel olarak anlamlı koroidal kalınlık ölçümleri saptanmadı (p>0.05). Sonuç: DKH çocuklar da yüksek hematokrit, düşük arteriyel oksijen saturasyonu veya aşırı volüm yükü nedeniyle olası retinal vasküler değişikler beklenmesine karşın, çalışmamızda DKH’lı hastaların normal koroidal kalınlık gösterdiklerini saptadık. Bu durum hastalarımızın çoğunda uygulanmış medikal yada cerrahi tedavi ile retinal vasküler değişiklerin iyileştirilmesine bağlı olabilir.

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Cite This Article

ŞEN, S., ALKAN, F., ÇAVDAR, E., COŞKUN, Ş. (2022). Choroidal Thickness in Children with Congenital Heart Disease Measured by Spectral Domain Optical Coherence Tomography§. İzmir Tepecik Eğitim Hastanesi Dergisi, Cilt: 31 - Sayı: 3, 338–343. https://ajindex.com/articles/557952

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References (1)

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