AI Summary & Key Takeaways
AI InsightThe most active quinolone against gram negative bacillus was ciprofloxacin (76.2 %) and it was followed by moxifloxacin (71.5 %), levofloxacin (71.1 %), and ofloxacin (60.7 %).
📌 3 Key Takeaways
Abstract
n this report, clinical samples of the patients with respiratory system infections were evaluated using bacteriologic culture methods. In-vitro susceptibility of the isolated bacteria to different quinolones were investigated and the results were compared. Of the 150 pathogen bacteria that were included in the study 97 (64.7%) of them were gram negative bacilli and 53 (35.3 %) of them were gram positive cocci. The most frequently isolated gram negative bacilli and gram positive bacteria cocci were Pseudomonas aeruginosa and methicilline sensitive Staphylococcus aureus (MSSA) respectively. When in-vitro activity of the quinolones were compared, the most active one against gram positive cocci was moxifloxacin (98.2 %) and it was followed by levofloxacin (95.2 %), ciprofloxacin (78 %), and ofloxacin (77.6 %). The most active quinolone against gram negative bacillus was ciprofloxacin (76.2 %) and it was followed by moxifloxacin (71.5 %), levofloxacin (71.1 %), and ofloxacin (60.7 %).
Özet
Bu çalışmada, solunum yolu infeksiyonu tanılı hastalardan alınan klinik örnekler bakteriyolojik kültür yöntemi ile incelendi. İzole edilen bakterilerin farklı kinolonlara duyarlılıkları in-vitro olarak incelendi ve sonuçlar karşılaştı-rıldı. Çalışmaya alınan 150 adet patojen bakteriden 97 (%64.7)’si gram olumsuz basil, 53 (%35.3)’ü gram olumlu kok idi. En sık izole edilen gram olumsuz basil ve gram olumlu kok sırası ile Pseudomonas aeruginosa ve metisilin duyarlı Staphylococcus aureus (MSSA) idi. Kinolonların in-vitro etkinlikleri karşılaştırıl-dığında gram olumlu koklara en etkin moksifloksasin (%98.2) idi. Bunu sırasıyla levofloksasin (%95.2), siprofloksasin (%78) ve ofloksasin (%77.6) izlemekte idi. Gram olumsuz basillere en etkin siprofloksasin (%76.2) idi. Bunu sırasıyla moksifloksasin (%71.5), levofloksasin (%71.1) ve ofloksasin (%60.7) izlemekte idi.