Objective & Hypothesis:In this study, to explore the effect of a single large dose ethanol on serum hepatic enzyme activities and lipid response, we administered 18 ml/kg of physiological saline and 4.5 g/kg b.w. ethanol to control rats (n=20) and experiment rats (n=20), respectively, and blood was taken 5 and 9 hours after alcohol administration.
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Key Findings & Data:In this study, to explore the effect of a single large dose ethanol on serum hepatic enzyme activities and lipid response, we administered 18 ml/kg of physiological saline and 4.5 g/kg b.w. ethanol to control rats (n=20) and experiment rats (n=20), respectively, and blood was taken 5 and 9 hours after alcohol administration.
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Conclusion & Impact:The increase in serumactivities of AST (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
In this study, to explore the effect of a single large dose ethanol on serum hepatic enzyme activities and lipid response, we administered 18 ml/kg of physiological saline and 4.5 g/kg b.w. ethanol to control rats (n=20) and experiment rats (n=20), respectively, and blood was taken 5 and 9 hours after alcohol administration. The increase in serumactivities of AST (p
Özet
Bu çalışmada yüksek doz etanol alımının serum, karaciğer enzim aktivite-leri ve lipid cevabına etkisini araştırmak amacıyla kontrol (n=20) ve deney (n=20) rat-larına sırasıyla 18 ml/kg fizyolojik serum ve 4.5 g/kg etanol oral yolla verildi ve 5. ve 9. saatlerde kan alındı. Alkol verildikten 5 saat sonra serum aspartat transferaz (AST) (p
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Cite This Article
TÜRKALP, I., ÖZBATAK, K., MENGİ, A., ÖZKAZANÇ, D., FIRAT, A., TÜRKMEN, G. (2022). The effect on serum enzyme activites and lipid levels in rats of single high dose ethanol. İstanbul Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 23 - Sayı: 2, 217–223. https://ajindex.com/articles/555665