Journals / İstanbul Üniversitesi Veteriner Fakültesi Dergisi / 1997 / Cilt: 23 - Sayı: 2

Effects of lectin on tumor development rat

Ratlarda tümör gelişimi üzerine lektin'in etkisi

Pages
255–271
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

The serum sialic acid levels of the healthy control group and the cancer control group demonstrated significant differences ( p

📌 3 Key Takeaways

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Objective & Hypothesis:In this study, to investigate the anticanserojenic effects of lectin, wistar albino type rats were given dimetylbenzoantrazen (DMBA) to induce tumor growth.
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Key Findings & Data:Rats with DMBA induced tumors were administrated lectin sub-cutancously (s.c) twice weekly at a dose of lng/kg for a period of 16 weeks.
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Conclusion & Impact:The serum sialic acid levels of the healthy control group and the cancer control group demonstrated significant differences ( p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In this study, to investigate the anticanserojenic effects of lectin, wistar albino type rats were given dimetylbenzoantrazen (DMBA) to induce tumor growth. Fifty rats were used. Rats were divided three groups as a healthy control, concer control and trial group. Rats with DMBA induced tumors were administrated lectin sub-cutancously (s.c) twice weekly at a dose of lng/kg for a period of 16 weeks. Blood samples were taken each month and levels of serum sialic acid, total protein and albumin were measured. The weights of the spleen and thymus were determined and these organs were pathologically assessed. Serum total protein and albumin levels didn't showed any significant statistical differences in the cancer group given lectin as compared to the control group. The serum sialic acid levels of the healthy control group and the cancer control group demonstrated significant differences ( p

Özet

Özet: Bu çalışmada, Lektinin antikanserojenik etkisini araştırmak amacıyla wistar albino tipi ratlarda Dimetilbenzoantrazen (DMBA) kullanılarak tümör oluşturul-muştur DMBA verilerek tümör oluşturulan ratlarda 16 hafta boyunca haftada iki kere I n»/kıT S.C. lektin uygulaması yapılarak, her ay alınan kan örneklerinde serum sialik asit, total protein ve albumin düzeylerine bakılmıştır. Timus, dalak ağırlıkları belirlenmiş ve organların patolojik incelemeleri yapılmıştır. Lektin uygulaması yapılan kanserli grupla kontrol grupları karşılaştırıldığında serum T. Protein ve albümin düzeylerinde istatistiki olarak anlamlı farklılıklar bulunamamıştır. Serum sialik asit düzeyinde ise sağlıklı kon¬trol grubu ile kanserli kontrol grubu değerleri arasında (p

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Cite This Article

TÜRKMEN, G., GÜREL, A., MENGİ, A., ÖZTABAK, K. (2022). Effects of lectin on tumor development rat. İstanbul Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 23 - Sayı: 2, 255–271. https://ajindex.com/articles/555626

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