Journals / İstanbul Tıp Dergisi / 2011 / Cilt: 12 - Sayı: 4

Bilateral hydronephrosis related to retroperitoneal fibrosis and response to steroid therapy: Case report

Retroperitoneal fibrozise bağlı bilateral hidronefroz ve steroid tedavisine yanıt: Olgu sunumu

Pages
187–190
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It should be kept in mind that this disease is an etiological factor causing obstructive uropathy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Retroperitoneal fibrosis (RPF) is a chronic inflammatory disease that often responds to steroid therapy.
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Key Findings & Data:A 65-year-old male patient admitted with the complaints of inability to urinate for three days.
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Conclusion & Impact:It should be kept in mind that this disease is an etiological factor causing obstructive uropathy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Retroperitoneal fibrosis (RPF) is a chronic inflammatory disease that often responds to steroid therapy. In this report, we present a patient admitted with anuria and bilateral hydronephrosis related to RPF and his quick response to steroid. A 65-year-old male patient admitted with the complaints of inability to urinate for three days. Laboratory tests revealed urea of 156 mg/dl and creatinine of 15 mg/dl. Abdominal computerized tomography (CT) scan showed an increased soft tissue density in the para aortic retroperitoneal region and bilateral urethral dilatation, and this image was noted as RPF. A double J (DJ) catheter was inserted and methylprednisolone 60 mg/day was started. On the seventh day, laboratory values were: urea: 32 mg/dl and creatinine: 1.1 mg/dl. On the follow-up CT scan two months after the treatment, RPF had regressed. The DJ catheter was withdrawn, and methylprednisolone was stopped with decreasing doses in six months. It should be kept in mind that this disease is an etiological factor causing obstructive uropathy.

Özet

Retroperitoneal fibrozis (RPF) steroid tedavisine sıklıkla yanıt veren kronik enflamatuvar hastalıktır. Bu yazıda, anüri nedeni ile başvuran, RPF’ye bağlı bilateral hidronefrozu tespit edilen ve steroide çok hızlı yanıt veren bir olgu sunuldu. Altmış beş yaşında erkek hasta, üç gündür idrar yapamama yakınması ile başvurdu. Laboratuvar testlerinde üre: 156 mg/dl, kreatinin: 15 mg/dl idi. Karın bilgisayarlı tomografisinde (BT) retroperitenal mesafede paraaortik alanlarda yaygın yumuşak doku yoğunluk artışı ve bilateral üreteral dilatasyon izlendi ve retroperitoneal fibrozis olarak yorumlandı. Hastaya duble J (DJ) kateter takıldı ve metilprednizolon 60 mg/gün başlandı. İşlem sonrası 7. gün üre 32 mg/dl, kreatinin 1.1 mg/dl ölçüldü. İki ay sonra BT kontrolünde RPF’nin gerilediği izlendi. Hastanın DJ kateteri çekildi ve steroid tedavisi azaltılarak, altıncı ayda kesildi. RPF, obstrüktif üropatinin etyolojik sebepleri arasında akılda tutulmalıdır.

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Cite This Article

DOĞAN, İ., KAHVECİOĞLU, S., GÜLLÜ, B. E., DAĞEL, T. (2022). Bilateral hydronephrosis related to retroperitoneal fibrosis and response to steroid therapy: Case report. İstanbul Tıp Dergisi, Cilt: 12 - Sayı: 4, 187–190. https://ajindex.com/articles/552546

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