Journals / İstanbul Medical Journal / 2013 / Cilt: 14 - Sayı: 1

The Contribution of Diffusion Weighted MRI (DWI) and Measured ADC Values in Differentiating Benign and Malignant Liver Masses

Karaciğer Kitlelerinde Malign-Benign Ayırımında Difüzyon Ağırlıklı MRG (DAG) ve ADC'nin Tanı Değeri

Pages
16–19
Publication Date
2022-10-19
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Diffusion weighted MRI and the quantitative ADC values measurements can be useful in the differential diagnosis of benign and malignant hepatic lesions

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The purpose of this study is to evaluate the contribution of dif- fusion weighted MRI and measured ADC values in differentiating benign and malignant liver masses.
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Key Findings & Data:Methods: Sixty patients who had liver masses more than 1 cm in diameter detected by routine upper abdominal MRI, were additionally examined with diffusion weighted MRI.
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Conclusion & Impact:Conclusion: Diffusion weighted MRI and the quantitative ADC values measurements can be useful in the differential diagnosis of benign and malignant hepatic lesions
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The purpose of this study is to evaluate the contribution of dif- fusion weighted MRI and measured ADC values in differentiating benign and malignant liver masses. Methods: Sixty patients who had liver masses more than 1 cm in diameter detected by routine upper abdominal MRI, were additionally examined with diffusion weighted MRI. Two different diffusion gradients (b values were b=0 and b=1000 mm2/s) were applied in three different directions (x, y, z) using single shot echo-planar SE with 1.5 T MR imager. Diffusion weighted images and ADC maps of 60 liver masses in 60 patients were obtained. Results: The number of benign and malignant masses were 39 and 21 re- spectively. Benign masses consisted of 12 simple cysts, 12 hemangiomas, 2 FNH, 1 hepatic adenoma, 1 crrhotic regenerative nodule, 3 abcesses and 8 hydatid cysts. Malignant masses were 14 metastatic lesions, 7 hepatocel- lular carcnomas. The ADC values of simple cysts and hemangiomas were the highest among all liver masses. The mean ADC values of benign and malignant liver masses were 3.01x10-3 mm2/s and 1.28 x 10-3 mm2/s respec- tively. The difference between mean ADC values of benign and malignant liver masses was significant (p=0.001). Conclusion: Diffusion weighted MRI and the quantitative ADC values measurements can be useful in the differential diagnosis of benign and malignant hepatic lesions

Özet

Amaç: Karaciğer kitlelerinin malign-benign ayırımında Difüzyon AğırlıklıMRG ve hesaplanan ADC değerlerinin tanıya katkısının araştırılması.Yöntemler: İstanbul Eğitim ve Araştırma Hastanesi Radyoloji Kliniği'nebaşvuran ve önceden bilinen veya diğer görüntüleme yöntemleriyle yerelkaraciğer kitlesi saptanan olgulara batın MRG değerlendirmesine ek olarakdifüzyon ağırlıklı MR sekansı uygulandı. 1,5 Tesla MR cihazında aksiyalplanda, single shot echo- planar spin eko sekansı ile her 3 yönde (x, y, z),2 farklı b değerinde (b=0 ve b=1000 mm2/s ) difüzyon duyarlı gradiyentleruygulanarak difüzyon ağırlıklı görüntüler ve ADC haritaları elde edildi. 60olgudaki karaciğer kitlelerinin ortalama ADC ölçümleri yapıldı.Bulgular: Altmış karaciğer kitlesinin 39 tanesi benign, 21 tanesi malignkitlelerdi. Benign kitleleri 12 kist, 12 hemanjiom, 2 fokal nodüler hiperplazi,1 hepatik adenom, 1 siroza bağlı rejenerasyon nodülü, 3 abse ve 8 kisthidatik oluşturuyordu. Malign kitleler ise 14 metastaz, 7 hepatosellülerkarsinom oluşmaktaydı. ADC ölçümleri sonucunda en yüksek değerler kistve hemanjiomlara aitti. Benign lezyonların ortalama ADC değeri 3.01x10-3mm2/s iken malign lezyonların ortalama ADC değeri 1.28x10-3 mm2/s olarakölçüldü. Benign lezyonların ortalama ADC değeri malign lezyonlardananlamlı ölçüde yüksekti (p=0.001).Sonuç: Difüzyon ağırlıklı MR görüntüleme ve işlem sırasında elde edilensayısal ADC değerleri ölçümleri, benign ve malign karaciğer kitlelerininayrımında yararlı olabilir

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Cite This Article

TUZCU, G., KARAGÖZ, Y., AYBAR, M. D., TURNA, Ö., BÜKER, A. (2022). The Contribution of Diffusion Weighted MRI (DWI) and Measured ADC Values in Differentiating Benign and Malignant Liver Masses. İstanbul Medical Journal, Cilt: 14 - Sayı: 1, 16–19. https://ajindex.com/articles/552247

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References (14)

  1. Semelka RC, Martin DR, Balci NC. Magnetic resonance imaging of the liver: how I do it. J Gastroenterol Hepatol 2006
  2. [CrossRef] 2. Altun E, Tüney D. Karaciğerin Fokal Lezyonlarının Tanısında MR ile Görütülemenin Rolü. Klinik Gelişim 2010
  3. Tello R, Fenlon HM, Gagliano T, deCarvalho VL, Yucel EK. Prediction rule for characterization of hepatic lesions revealed on MR imaging: estimation of malignancy. AJR 2001
  4. [CrossRef] 4. Demir OI, Obuz F, Sağol O, Dicle O. Contribution of diffusion-weighted MRI to the differential diagnosis of hepatic masses. Diagn Interv Radiol 2007
  5. van Everdingen KJ, van der Grond J, Kappelle LJ, Ramos LM, Mali WP. Diffusion-weighted magnetic resonance imaging in acute stroke. Stroke 1998
  6. [CrossRef] 6. Back T, Hoehn-Berlage M, Kohno K, Hossmann KA. Diffusion nuclear magnetic resonance imaging in experimental stroke. Correlation with cerebral metabolites. Stroke 1994
  7. [CrossRef] 7. Le Bihan D, Turner R, Douek P, Patronas N. Diffusion MR imaging: clinical applications. AJR Am J Roentgenol 1992
  8. [CrossRef] 8. Yoshikawa T, Kawamitsu H, Mitchell DG, Ohno Y, Ku Y, Seo Y. ADC measurement of abdominal organs and lesions using parallel imaging technique. AJR Am J Roentgenol 2006
  9. [CrossRef] 9. Ichikawa T, Haradome H, Hachiya J, Nitatori T, Araki T. Diffusion-weighted MR imaging with a single-shot echoplanar sequence: detection and characterization of focal hepatic lesions. AJR Am J Roentgenol 1998
  10. [CrossRef] 10. Yamada I, Aung W, Himeno Y, Nakagawa T, Shibuya H. Diffusion coefficients in abdominal organs and hepatic lesions: evaluation with intravoxel incoherent motion echo-planar MR imaging. Radiology 1999
  11. Cova M, Squillaci E, Stacul F, Manenti G, Gava S, Simonetti G. Diffusion-weighted MRI in the evaluation of renal lesions: preliminary results. Br J Radiol 2004
  12. [CrossRef] 12. Phongkitkarun S, Srianujata T, Jatchavala J. Supplement value of magnetic resonance imaging in small hepatic lesion (_____ or = 20 mm) detected on routine computed tomography. J Med Assoc Thai 2009
  13. Sandrasegaran K, Akisik FM, Lin C, Tahir B, Rajan J, Aisen AM. The value of diffusion-weighted imaging in characterizing focal liver masses. Acad Radiol 2009
  14. [CrossRef] 14. Sun XJ, Quan XY, Huang FH, Xu YK. Quantitative evaluation of diffusion-weighted magnetic resonance imaging of focal hepatic l