Journals / İstanbul Medical Journal / 2014 / Cilt: 15 - Sayı: 1

Comparision of Central Corneal Thickness between Patients with Pseudoexfoliation Syndrome and Normal Subjects

Psödoeksfoliasyon Sendromlu Olguların Santral Kornea Kalınlıklarının Normal Bireylerle Karşılaştırılması

Pages
48–50
Publication Date
2022-10-19
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The CCTvalues were measured with ultrasound pachymetry and compared betweengroups.Results: Mean CCT was statistically significantly thinner in PES eyes(539.99±37.1 ?m) than in normal eyes (558.62±30.67 ?m) (p=0.0001).There was no statistically significant difference in mean CCT between thePES eyes with and without glaucoma (541.94±29.32 ?m, 538.23±39.03?m, respectively) (p=0.724).Conclusion: Thinner CCT in eyes with PES, as a result of artificially lowerintraocular pressure readings, may cause late diagnosis of glaucoma andrapid progression of the disease.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: We aimed to compare the central corneal thickness (CCT) measurementsof the cases with pseudoexfoliation syndrome (PES) and normalsubjects.Methods: Sixty eyes of 30 control cases and 58 eyes of PES patients withand without glaucoma were included in our prospective study.
📊
Key Findings & Data:Objective: We aimed to compare the central corneal thickness (CCT) measurementsof the cases with pseudoexfoliation syndrome (PES) and normalsubjects.Methods: Sixty eyes of 30 control cases and 58 eyes of PES patients withand without glaucoma were included in our prospective study.
💡
Conclusion & Impact:The CCTvalues were measured with ultrasound pachymetry and compared betweengroups.Results: Mean CCT was statistically significantly thinner in PES eyes(539.99±37.1 ?m) than in normal eyes (558.62±30.67 ?m) (p=0.0001).There was no statistically significant difference in mean CCT between thePES eyes with and without glaucoma (541.94±29.32 ?m, 538.23±39.03?m, respectively) (p=0.724).Conclusion: Thinner CCT in eyes with PES, as a result of artificially lowerintraocular pressure readings, may cause late diagnosis of glaucoma andrapid progression of the disease.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: We aimed to compare the central corneal thickness (CCT) measurementsof the cases with pseudoexfoliation syndrome (PES) and normalsubjects.Methods: Sixty eyes of 30 control cases and 58 eyes of PES patients withand without glaucoma were included in our prospective study. The CCTvalues were measured with ultrasound pachymetry and compared betweengroups.Results: Mean CCT was statistically significantly thinner in PES eyes(539.99±37.1 ?m) than in normal eyes (558.62±30.67 ?m) (p=0.0001).There was no statistically significant difference in mean CCT between thePES eyes with and without glaucoma (541.94±29.32 ?m, 538.23±39.03?m, respectively) (p=0.724).Conclusion: Thinner CCT in eyes with PES, as a result of artificially lowerintraocular pressure readings, may cause late diagnosis of glaucoma andrapid progression of the disease.

Özet

Amaç: Psödoeksfoliasyon sendromlu (PES) olguların santral kornea kalınlık(SKK) değerlerini normal bireylerle karşılaştırmayı amaçladık.Yöntemler: Glokomu olan ve olmayan PES'li 39 hastanın 58 gözü ile 30kontrol olgunun 60 gözü prospektif çalışmamız kapsamına alındı. SKKdeğerleri ultrasonik pakimetri cihazıyla ölçülerek gruplar arasında karşılaştırıldı.Bulgular: Psödoeksfoliasyon sendromlu gözlerin ortalama SKK'ları(539,99±37,1 ?m) normal gözlerden (558,62±30,67 ?m) istatistiksel olarakanlamlı derecede düşük bulunmuştur (p=0,0001). Glokomu olan veolmayan PES'li gözler arasında SKK ortalamaları açısından istatistiksel olarakanlamlı bir fark bulunmamıştır (541,94±29,32 ?m, 538,23±39,03 ?msırasıyla) (p=0,724).Sonuç: Psödoeksfoliasyon sendromlu gözlerde SKK'nın daha ince olması,yapay düşük göz içi basıncı ölçüm sonucu olarak glokom tanısının gecikmesineve hastalığın hızlı progresyonuna neden olabilir.

🔖

Cite This Article

YILMAZ, T., AKDEMİR, M. O., KALDIRIM, H., MERT, M., ŞEREFOĞLU, K. Ç., KIRGIZ, A. (2022). Comparision of Central Corneal Thickness between Patients with Pseudoexfoliation Syndrome and Normal Subjects. İstanbul Medical Journal, Cilt: 15 - Sayı: 1, 48–50. https://ajindex.com/articles/552237

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (3)

  1. Newell F. The glaucomas. In: Newell F, ed. Ophthalmology. Principles and Concepts. St Louis: Mosby; 1992.p.380-1. Skuta G. Pseudoexfoliation syndrome, pigment dispersion syndrome and the associated glaucomas. In: TasmanW, Jaeger EA, eds. Duane's Clinical Ophthalmology. Philadelphia: JB Lippincott; 1989.p.1-10.
  2. Schlötzer-Schrehardt U, Naumann GO. Ocular and systemic pseudoex- foliation syndrome. Am J Ophthalmol 2006; 141: 921-37. [CrossRef] Naumann GOH, Schlotzer-Schrehardt U, Küchle M. Pseudoexfoliation syndrome for the comprehensive ophthalmologist. Intraocular and systemic manifestations. Ophthalmology 1998; 105: 951-68. [CrossRef] Mitchell P, Wang JJ, Hourihan F. The relationship between glaucoma and pseudoexfoliation: The Blue Mountains Eye Study. Arch Ophthal- mol 1999; 117: 1319-24. [CrossRef] Özturk F, Küsbeci T, Yavas G, Ermis SS, Kaplan U, İnan UU. Pascal di- namik kontur tonometre ile ölculen goz ici basınc değerlerinin Gold- mann Applanasyon tonometresi, non-kontakt tonometre ve tonopen ile karsılastırılması ve santral kornea kalınlığının etkisi. Glokom-Kata- rakt 2006; 1: 171-5.
  3. Herndon LW, Choudhri SA, Cox T, Damji KF, shields BM, Allingham BRR. Central corneal thickness in normal, glaucomatous and ocular hypertensive eyes. Arch Ophthalmol 1997; 115: 1137-41. [CrossRef] Argus WA. Ocular hypertension and central corneal thickness. Oph- thalmology 1995; 102: 1810-2. [CrossRef] Gorezis S, Christos G, Stefaniotou M, Moustaklis K, Skyrlas A, Kitsos G, et al. Comparative results of central corneal thickness measurements in primary open-angle glaucoma, pseudoexfoliation glaucoma, and ocular hypertension. Ophthalmic Surg Lasers Imaging 2008; 39: 17- 21. [CrossRef] Hepsen IF, Yağci R, Keskin U. Corneal curvature and central corneal thickness in eyes with pseudoexfoliation syndrome. Can J Ophthalmol 2007; 42: 677-80. [CrossRef] Puska P, Vasara K, Harju M, Setälä K. Corneal thickness and corne- al endothelium in normotensive subjects with unilateral exfoliati- on syndrome. Graefes Arch Clin Exp Ophthalmol 2000; 238: 659-63. [CrossRef] Stodtmeister R. Applanation tonometry and correction according to corneal thickness. Acta Ophthalmol Scand 1998; 76: 319-24. [CrossRef] Ehlers N, Bramsen T, Sperling S. Applanation tonometry and central corneal thickness. Acta Ophthalmol 1975; 53: 34-43. [CrossRef] Goldmann H, Schmidt T. Ueber applanationtonometrie. Ophthalmo- logica 1957; 134: 221-41. [CrossRef] Kim JW, Chen PP. Central corneal pachymetry and visual field