Journals / İstanbul Medical Journal / 2014 / Cilt: 15 - Sayı: 1

The Endoscopic Findings and Clinical Management in Patients Were Hospitalized for Upper Gastrointestinal Bleeding Using Oral Anticoagulants

Üst Gastrointestinal Sistem Kanaması ile Başvuran Hastalarda Oral Antikoagülan Kullanım Birlikteliği, Endoskopi Bulguları ve Klinik Yönetimi

Pages
9–15
Publication Date
2022-10-19
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Gender,and length of hospital aspirin use, mortality, endoscopic findings, wassimilar in men and women in patients using OAC or not-using.Conclusion: As a result, the use of OAC and supratherapeutic INR value donot increase the risk of upper gastrointestinal bleeding, if there is no anunderlying gastric pathology.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The purpose of this study was to identify the underlying pathologyof gastric bleeding and the patient's clinical condition to determinethe effect of triggering is to reveal in patients were hospitalized for uppergastrointestinal bleeding in patients using oral anticoagulants.Methods: In this study, between January 1st 2007 and December 31st 2010Ministry of Health İstanbul Education and Research Hospital, InternalMedicine Clinics, who were hospitalized with a diagnosis of upper gastrointestinalbleeding in 70 patients using oral anticoagulantsand not usingoral anticoagulant 229 patients were evaluated retrospectively.
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Key Findings & Data:Filesexaminated about the patient gender, age, presenting symptoms, the applicationof hemoglobin and INR values, a history of aspirin use, smokingand drinking history, presence of concomitant disease, endoscopy reports,duration of hospitalization, need for transfusion, need for emergency surgery,mortality.Results: The use of aspirin, recurrent bleeding rate, emergency surgery,mortality, in terms of length of stay and the complaint was similar in thetwo groups.
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Conclusion & Impact:Gender,and length of hospital aspirin use, mortality, endoscopic findings, wassimilar in men and women in patients using OAC or not-using.Conclusion: As a result, the use of OAC and supratherapeutic INR value donot increase the risk of upper gastrointestinal bleeding, if there is no anunderlying gastric pathology.
🔬Design:Research Article
📍Scope:2007 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The purpose of this study was to identify the underlying pathologyof gastric bleeding and the patient's clinical condition to determinethe effect of triggering is to reveal in patients were hospitalized for uppergastrointestinal bleeding in patients using oral anticoagulants.Methods: In this study, between January 1st 2007 and December 31st 2010Ministry of Health İstanbul Education and Research Hospital, InternalMedicine Clinics, who were hospitalized with a diagnosis of upper gastrointestinalbleeding in 70 patients using oral anticoagulantsand not usingoral anticoagulant 229 patients were evaluated retrospectively. Filesexaminated about the patient gender, age, presenting symptoms, the applicationof hemoglobin and INR values, a history of aspirin use, smokingand drinking history, presence of concomitant disease, endoscopy reports,duration of hospitalization, need for transfusion, need for emergency surgery,mortality.Results: The use of aspirin, recurrent bleeding rate, emergency surgery,mortality, in terms of length of stay and the complaint was similar in thetwo groups. In addition, in our study, endoscopy results of the using oralanticoagulation in patients was lower than the literature. In our study,patients using oral anticoagulant (OAC) association of H. pylori has beenfound less likely than non-users. Concurrent use of aspirin did not affectthe findings of endoscopy in both patient groups. Length of hospital stayin patients using OAC with recurrent bleeding, was more than other group.The first and recurrent hemorrhage, mortality, use of aspirin, gender didnot differ among patients with upper gastrointestinal bleeding. Gender,and length of hospital aspirin use, mortality, endoscopic findings, wassimilar in men and women in patients using OAC or not-using.Conclusion: As a result, the use of OAC and supratherapeutic INR value donot increase the risk of upper gastrointestinal bleeding, if there is no anunderlying gastric pathology.

Özet

Amaç: Çalışmanın amacı üst gastrointestinal sistem kanamasıyla yatışı yapılmışolan hastalarda kanamanın oral antikoagülan kulanımıyla ilgisinitespit etmek, altta yatan gastrik patalojinin kanamayı tetikleyip tetiklemediğinisaptamak ve hastanın klinik durumuna etkisini ortaya koymaktır.Yöntemler: Bu çalışmada, 1 Ocak 2007 ve 31 Aralık 2010 tarihleri arasındaSağlık Bakanlığı İstanbul Eğitim ve Araştırma Hastanesi Dahiliye Klinik'lerindeüst gastrointestinal (GİS) kanaması teşhisi ile yatırılarak tedavi edilenoral antikoagülan kullanan 70 hasta ve oral antikoagülan kullanmayan229 hasta retrospektif olarak değerlendirilmiştir. Ulaşılan dosyalar incelenerekhasta cinsiyeti, yaşı, başvuru şikayeti, başvuru hemoglobin veinternasyonel normalized ratio (INR) değerleri, aspirin kullanım öyküsü,sigara ve alkol kullanım öyküsü, ek hastalık varlığı, endoskopi raporları,hastanede yatış süresi, transfüzyon ihtiyacı, acil cerrahi ihtiyacı, mortaliteile ilgili bilgiler elde edildi.Bulgular: Aspirin kullanımı, rekürren kanama oranı, acil cerrahi gereksinimi,mortalite, başvuru şikayeti ve yatış süresi açısından her iki grup benzerbulunmuştur. Bunun yanı sıra bizim çalışmamızda endoskopi yapılanoral antikoagülan kullanan ve kullanmayan olgularda normal endoskopisonucu literatürden daha düşük izlenmiştir. Çalışmamızda oral anti koagülan(OAK) kullanan olgularda kullanmayanlara göre daha az oranda H.pylori birlikteliği tespit edilmiştir. Eş zamanlı aspirin kullanımı her iki hastagrubunda da endoskopi bulgularını etkilememiştir. Rekürren kanamalıOAK kullanmayan olgularda hastanede yatış süresi daha fazla bulunmuş,bunun dışında OAK kullanan ve OAK kullanamayan üst GİS kanamalı olgulararasında kanamanın ilk ve rekürren oluşuna göre yaş, mortalite, aspirinkullanımı, cinsiyet açısından farklılık bulunmamıştır. OAK kullananve OAK kullanmayan olgularda cinsiyetle hastanede yatış süreleri, aspirinkullanımı, mortalite, endoskopi bulguları ilişkilendirilmeye çalışılmış, kadınve erkek de benzer bulunmuştur.Sonuç: Tek başına OAK kullanımı ve supraterpatik INR değeri altta yatangastrik pataloji olmadığı takdirde üst GİS kanama riskini arttırmamaktadır.

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Cite This Article

MÜDERRİSOĞLU, C., POLAT, H., KULUCAN, C., ULAŞ, N., YILDIRIM, A. M. B. (2022). The Endoscopic Findings and Clinical Management in Patients Were Hospitalized for Upper Gastrointestinal Bleeding Using Oral Anticoagulants. İstanbul Medical Journal, Cilt: 15 - Sayı: 1, 9–15. https://ajindex.com/articles/552210

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