Journals / İstanbul Medical Journal / 2014 / Cilt: 15 - Sayı: 2

Extraordinary Pancreatic Masses

Sıradışı Pankreas Kitleleri

Pages
110–112
Publication Date
2022-10-19
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Early diagnosis of these lesions is still a challenge that we must overcome

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In this study, in light of current literature; we studied the diagnostic-therapeutic and prognostic features of pancreatic lesions located in the body and tail, for which we performed distal pancreatectomy.Methods: Ten patients with pancreatic lesions, who were treated surgically with distal pancreatectomy between the years 2005-2010, in the General Surgery Clinics of Istanbul Education and Research Hospital, were analyzed retrospectively, regarding their demographic-clinical-pathological features and diagnostic methods.Results: Three of the patients were male and 7 were female.
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Key Findings & Data:The median age of patients was 57.2 (the youngest 27, the oldest 81), with 3 of them having lesions located in the tail and 7 in the body of the pancreas.
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Conclusion & Impact:Early diagnosis of these lesions is still a challenge that we must overcome
🔬Design:Research Article
📍Scope:2005-2010 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: In this study, in light of current literature; we studied the diagnostic-therapeutic and prognostic features of pancreatic lesions located in the body and tail, for which we performed distal pancreatectomy.Methods: Ten patients with pancreatic lesions, who were treated surgically with distal pancreatectomy between the years 2005-2010, in the General Surgery Clinics of Istanbul Education and Research Hospital, were analyzed retrospectively, regarding their demographic-clinical-pathological features and diagnostic methods.Results: Three of the patients were male and 7 were female. The median age of patients was 57.2 (the youngest 27, the oldest 81), with 3 of them having lesions located in the tail and 7 in the body of the pancreas. All of the patients underwent distal pancreatectomy, 5 of which had additional splenectomy. Their pathologic examinations revealed 3 serous cystadenomas, 2 mucinous cystic neoplasms, 2 solid pseudopapillary tumors, 1 ductal adenocarcinoma, 1 acinary cell carcinoma, and 1 neuroendocrine tumor. The median follow-up interval was 2 years.Conclusion: Tumors of the pancreatic tail and body are extraordinary lesions, with low malignant potential. Most of the patients are young females. The most common complaint is abdominal pain or a palpable abdominal mass, with 50% being asymptomatic. These lesions are prone to local invasion. Prognosis is excellent, following a complete surgical resection, and recurrence is uncommon. Diagnosis and treatment of pancreatic cancer are still a major concern, due to its poor prognosis. Because there are no specific early findings, symptoms appear only when it compresses or invades the neighboring structures. Curative resection is possible in 10%-20% and 15% of pancreatic masses located in the body and tail, respectively. Early diagnosis of these lesions is still a challenge that we must overcome

Özet

Amaç: Bu çalışmada, pankreasın gövde ve distalinde yerleşim gösteren ve distal pankreatektomi uyguladığımız sıradışı pankreas lezyonları; tanı-tedavi ve prognoz açısından güncel literatür bilgileri eşliğinde incelendi.Yöntemler: 2005-2010 yılları arasında İstanbul Eğitim ve Araştırma Hastanesi'nde distal pankreatektomi uyguladığımız 10 olgu, retrospektif olarak incelendi. Hastaların demografik, klinik, patolojik özellikleri ve tanı yöntemleri değerlendirildi.Bulgular: Hastaların 3'ü erkek 7'si kadındı. Yaş ortalaması 57,2 (en küçük 27-en büyük 81) idi. Olguların 3'ünde lezyon (%30) pankreas gövdesinde, 7'sinde (%70) kuyruk yerleşimliydi. Tüm hastalara distal pankreatektomi uygulandı. 5 hastaya, splenektomi de eklendi. Olgular patolojik açıdan değerlendirildiğinde; 3 olguda seröz kistadenom, 2 olguda solid psödo-papiller tümör, 2 olguda müsinöz kistik neoplazm, 1 olguda duktal ade-nokarsinom, 1 olguda asiner hücreli karsinom, 1 olguda ise nöroendokrin tümör tesbit edildi. Hastalar, ortalama 2 yıl süreyle takip edildiler.Sonuç: Pankreasın gövde ve kuyruk yerleşimli sıradışı lezyonları; düşük derecede malignite potansiyeli taşıyan ve nadir görülen lezyonlardır. Has-taların çoğu genç kadınlardır. %50 hasta asemptomatik olup, en sık karın-da kitle ya da karın ağrısı şikayeti ile başvururlar. Bu lezyonlar, daha çok lokal invazyon yapma eğilimindedirler. Tam rezeksiyon sonrası prognoz mükemmeldir ve rekürrens çok nadir görülür. Pankreas kanseri ise, kötü prognozu ile tanı ve tedavideki önemini korumaktadır. Pankreas kanserine özgü erken dönem bulguları yoktur. Genellikle çevre dokulara bası ya da in-vazyon yapınca semptomlar ortaya çıkar. Pankreas başı kanserlerinin %10-20'sine, gövde ve kuyruktaki tümörlerin ise ancak %15'ine küratif rezeksiyon yapılabilmektedir. Bu lezyonların erkenden ve doğru şekilde tanınması, aşıl-ması gereken bir sorun olarak durmaktadır.

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Cite This Article

TOROS, A. B., BEKTAŞ, H., PAŞAOĞLU, E., KARAGÖZ, Y., BÜYÜKAŞIK, K., ARI, A. (2022). Extraordinary Pancreatic Masses. İstanbul Medical Journal, Cilt: 15 - Sayı: 2, 110–112. https://ajindex.com/articles/552203

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