Journals / İstanbul Medical Journal / 2015 / Cilt: 16 - Sayı: 1

Fibrin Membrane Pupillary-Block Glaucoma After Uneventful Cataract Surgery Treated with Intracameral Tissue Plasminogen Activator: A Case Report

Komplikasyonsuz Katarakt Ameliyatından Sonra Gelişen Fibrin Membran Pupiller Blok Glokomunun İntrakamaral tPA İle Tedavisi: Olgu Sunumu

Pages
42–44
Publication Date
2022-10-19
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Fibrin-dependent PBG was successfully treated with an intracameral injection of tPA

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: To evaluate the diagnostic and therapeutic methods of fibrindependent pupillary-block glaucoma (PBG).
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Key Findings & Data:Methods: A 79-year-old male patient with hypertension was admitted to hospital with symptoms of pain and redness 6 days after an uneventful cataract surgery.
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Conclusion & Impact:Fibrin-dependent PBG was successfully treated with an intracameral injection of tPA
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: To evaluate the diagnostic and therapeutic methods of fibrindependent pupillary-block glaucoma (PBG). Methods: A 79-year-old male patient with hypertension was admitted to hospital with symptoms of pain and redness 6 days after an uneventful cataract surgery. Results: He had acute elevation of intraocular pressure with a shallow anterior chamber. Because of severe corneal edema, the anterior chamber details could not be distinguished. After systemic and topical antiglaucoma treatment, corneal edema was reduced and a complete fibrin membrane was observed across the pupil on slit lamp examination. A complete fibrin membrane across the pupillary space, shallow anterior chamber, and deep posterior chamber was confirmed by ultrasonic biomicroscopy (UBM). The intraocular lens (IOL) was actually displaced posteriorly, with a large clear space between the IOL and iris. Despite topical and subconjunctival corticosteroid therapy as well as Nd:YAG laser membranotomy, the fibrin membrane was not resolved. Tissue plasminogen activator (tPA) (25 ?g) was injected intracamerally and the fibrin membrane was completely dissolved, improving the pupillar block. Conclusion: Anterior segment imaging techniques, especially UBM, are a powerful diagnostic technique for differentiating the technique for the analysis of the mechanisms underlying acute angle-closure glaucoma mechanism. Fibrin-dependent PBG was successfully treated with an intracameral injection of tPA

Özet

Amaç: Fibrine bağlı pupiller blok glokomunun (PBG) tanı ve tedavi yöntemlerini değerlendirmek. Yöntem: 79 yaşında hipertansiyon öyküsü olan erkek hasta sorunsuz bir katarakt cerrahisinden 6 gün sonra kızarıklık ve ağrı şikayeti ile müracaat etti. Bulgular: Hastanın göziçi basıncı (GİB) yüksekti ve sığ bir ön kamara mevcuttu. Şiddetli korneal ödem nedeniyle ön kamarada ayrıntı seçilemiyordu. Sistemik ve topikal anti glokom tedavi ile korneal ödem azaldığında biomikroskobik muayene ile pupil alanını tamamen örten fibrin membran gözlendi. Ultrasonik biomikroskopi (UBM) ile pupillar alanı örten fibrin membran, ön kamarada daralma ve derin bir arka kamara tespit edildi. İris ile GİL arasında geniş saydam bir boşluk mevcuttu ve İOL daha geride yerleşmişti. Topikal ve subkonjonktival kortikosteroid tedavisi ve Nd: YAG laser membranotomiye rağmen fibrin membran çözülmedi. Ön kamaraya 25 µgr doku plazminojen aktivatörü (tPA) enjekte edildi, fibrin membran tamamen çözüldü ve pupillar blok düzeldi. Sonuç: Ön segment görüntüleme yöntemleri, özellikle UBM, akut açı kapanması glokom mekanizmasının ayırımında önemli bir tanısal tetkiktir. Fibrine bağlı PBG, intra kamaral tPA enjeksiyonu ile başarılı bir şekilde tedavi edilmiştir.

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Cite This Article

DİNÇER, N., AKÇETİN, T. A., ÖZDEMİR, F. E., ELTUTAR, K. (2022). Fibrin Membrane Pupillary-Block Glaucoma After Uneventful Cataract Surgery Treated with Intracameral Tissue Plasminogen Activator: A Case Report. İstanbul Medical Journal, Cilt: 16 - Sayı: 1, 42–44. https://ajindex.com/articles/552159

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References (2)

  1. Yoshino H, Seki M, Ueda J, Yoshino T, Fukuchi T, Abe H. Fibrin memb- rane pupillary-block glaucoma after uneventful cataract surgery tre- ated with intracameral tissue plasminogen activator: a case report. BMC Ophthalmol 2012; 12: 3 [CrossRef] Khor WB, Perera S, Jap A, Ho CL, Hoh ST. Anterior segment imaging in the management of postoperative fibrin pupillary-block glaucoma. J Cataract Refract Surg 2009; 35: 1307-12. [CrossRef] Jaffe GJ, Lewis H, Han DP, Williams GA, Abrams GW. Treatment of post- vitrectomy fibrin pupillary block with tissue plasminogen activator. Am J Ophthalmol 1989; 108: 170-5. [CrossRef] Mansouri K, Sommerhalder J, Shaarawy T. Prospective comparison of ultrasound biomicroscopy and anterior segment optical coherence tomography for evaluation of anterior chamber dimensions in Euro- pean eyes with primary angle closure. Eye 2010; 24: 233-9. [CrossRef] Krupsky S, Zalish M, Oliver M, Pollack A. Anterior segment complica- tions in diabetic patients following extracapsular cataract extraction and posterior chamber intraocular lens implantation. Ophthalmic Surg 1991; 22: 526-30.
  2. Ozveren F, Eltutar K. Therapeutic application of tissue plasminogen activator for fibrin reaction after cataract surgery. J Cataract Refract Surg 2004; 30: 1727-31. [CrossRef] Norris JW, Chirls IA, Santry JG, Norris JW III. Severe fibrinous reaction after cataract and intraocular lens implantation surgery requiring ne- odymium: YAG laser therapy. J Cataract Refract Surg 1990; 16: 637-9. [CrossRef] Lewis H, Han D, Williams GA: Management of fibrin pupillary-block glaucoma after pars plana vitrectomy with intravitreal gas injection. Am J Ophthalmol 1987; 103: 180-2. [CrossRef] Jaffe GJ, Lewis H, Han DP, Williams GA, Abrams GW. Treatment of post- vitrectomy fibrin pupillary block with tissue plasminogen activator. Am J Ophthalmol 1989; 108: 170-5. [CrossRef] Heiligenhaus A, Steinmetz B, Lapuente R, Krallmann P, Althaus C, Ste- inkamp WK, et al. Recombinant tissue plasminogen activator in cases with fibrin formation after cataract surgery: a prospective randomi- 44 zed multicentre study. Br J Ophthalmol 1998, 82: 810-5.[CrossRef]