Journals / İstanbul Medical Journal / 2015 / Cilt: 16 - Sayı: 2

Evaluation of Patients with Synchronous Bilateral Breast Cancer

Senkron Bilateral Meme Kanserli Hastaların Değerlendirilmesi

Pages
45–47
Publication Date
2022-10-19
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Hence, patients should be evaluated for the risk of contralateral breast cancer carefully at the same time of diagnosis.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Breast cancer is the most common cancer in women.
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Key Findings & Data:The incidence of bilateral breast cancer is 2%-11%.
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Conclusion & Impact:Hence, patients should be evaluated for the risk of contralateral breast cancer carefully at the same time of diagnosis.
🔬Design:Research Article
📍Scope:2010 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Breast cancer is the most common cancer in women. The incidence of bilateral breast cancer is 2%-11%. Synchronous bilateral breast cancer is uncommon (1%-2%). Bilateral breast cancer has worse prognosis than unilateral cancer. The aim of the retrospective study was to evaluate the incidence and demographic features of synchronous bilateral breast cancer patients in our hospital. Methods: We analyzed 266 breast cancer patients who were treated at our oncology department between January 2010 and December 2013. Five patients had synchronous bilateral breast cancer that was diagnosed at the same time. Results: We determined that five (1.87%) patients had synchronous bilateral breast cancer in this study. Of the five patients, one was a man and four were women. Median age was 53 years (40-64). Two patients were in premenopausal status. One patient revealed a positive family history of first-degree relatives. All of the patients had estrogen receptor positivity and invasive ductal carcinoma histopathology. Neoadjuvant chemotherapy was given to four patients. Only one metastatic patient had palliative chemotherapy. All patients had modified radical mastectomies and postoperative radiation therapy for bilateral breast cancer. Conclusion: Our clinical findings show a correlation with literature knowledge. Synchronous bilateral breast cancer is uncommon, and published data indicates worse prognosis. Hence, patients should be evaluated for the risk of contralateral breast cancer carefully at the same time of diagnosis.

Özet

Amaç: Meme kanseri kadınlarda en sık görülen kanserdir. Bilateral meme kanseri görülme oranı %2-11 arasındadır. Senkron bilateral meme kanseri nadirdir (%1-2). Tek taraflı meme kanserine göre prognoz daha kötüdür. Bu retrospektif çalışmanın amacı hastanemizdeki senkron bilateral meme kanseri vakalarının sıklığını belirlemek ve demografik özelliklerini ortaya koymaktır Yöntemler: Ocak 2010-Aralık 2013 yılları arasında başvuran 266 meme kanseri tanılı hasta retrospektif olarak değerlendirdi. Bu hastalardan beşinde tanı anında senkron bilateral meme kanseri saptandı. Bulgular: Bu çalışmada senkron bilateral meme kanseri tanılı 5 (%1.8) olgu değerlendirildi. Bir erkek dört kadın hastanın median yaşı 53'tü (40-64). Hastaların ikisi premenopozaldi. Sadece bir hastanın birinci dereceden akrabasında meme kanseri öyküsü vardı. Tüm hastaların östrojen reseptörleri pozitif ve hepsi invaziv duktal karsinom histolojisindeydi. Dört hastaya neoadjuvan, tanı anında metastaz saptanan bir hastaya palyatif kemoterapi uygulandı. Neoadjuvan tedavi alan hastaların hepsine modifiye radikal mastektomi yapılmış ve postoperatif radyoterapi tedavisi uygulanmıştır. Sonuç: Çalışmamızın bulguları literatür bilgisiyle uyumlu bulunmuştur. Senkron bilateral meme kanseri nadir görülür ve kötü prognozludur. Bu yüzden hastalar karşı memede kanser gelişimi açısından tanı aldıktan sonra dikkatli değerlendirilmelidir.

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Cite This Article

OKUTURLAR, Y., TUNA, S., GÜNALDI, M., TİKEN, E. E. (2022). Evaluation of Patients with Synchronous Bilateral Breast Cancer. İstanbul Medical Journal, Cilt: 16 - Sayı: 2, 45–47. https://ajindex.com/articles/552142

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