Here, we present a case of interstitial pneumonia due to everolimus, which can be confused with COVID-19 pneumonia due to its ground-glass appearance during the pandemic period.
📌 3 Key Takeaways
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Objective & Hypothesis:Ground glass appearance is a nonspecific finding that can see in diseases such as chronic interstitial disease, acute alveolar disease or infection; however, it is most commonly encountered in COVID-19 pulmonary involvement today.
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Key Findings & Data:The mammalian target of rapamycin (mTOR) plays a regulatory role in cell proliferation and growth.
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Conclusion & Impact:Here, we present a case of interstitial pneumonia due to everolimus, which can be confused with COVID-19 pneumonia due to its ground-glass appearance during the pandemic period.
🔬Design:Case Report
📍Scope:Comprehensive Sample
⚙️Variables:Everolimus · mTOR · ground glass
Abstract
Ground glass appearance is a nonspecific finding that can see in diseases such as chronic interstitial disease, acute alveolar disease or infection; however, it is most commonly encountered in COVID-19 pulmonary involvement today. The mammalian target of rapamycin (mTOR) plays a regulatory role in cell proliferation and growth. Everolimus is an allosteric mTOR inhibitor used in ER+ breast cancers and inhibits the mTOR functional complex. Here, we present a case of interstitial pneumonia due to everolimus, which can be confused with COVID-19 pneumonia due to its ground-glass appearance during the pandemic period.
Yiğit, S. E., Gökmen, İ. B., Okuturlar, Y. (2022). Ground Glass Appearance During the Pandemic Period: Everolimus Induced Interstitial Pneumonia. Turkish Journal of Internal Medicine, Volume: 4 Special Issue. https://doi.org/10.46310/tjim.1078775
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