Journals / İstanbul Medical Journal / 2016 / Cilt: 17 - Sayı: 3

Insulin Allergy

İnsülin Allerjisi

Pages
77–81
Publication Date
2022-10-19
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

De- sensitization therapy is a good option for patients with multiple insulin sensitizations

📌 3 Key Takeaways

🎯
Objective & Hypothesis:At present, hypersensitivity reactions to human insulins and insulin ana- logs are rare, although these reactions were relatively common when bovine and porcine insulins were used.
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Key Findings & Data:Local reactions may decrease insulin absorption, which may disrupt blood glucose regulation.
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Conclusion & Impact:De- sensitization therapy is a good option for patients with multiple insulin sensitizations
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

At present, hypersensitivity reactions to human insulins and insulin ana- logs are rare, although these reactions were relatively common when bovine and porcine insulins were used. Clinical presentation can range from local reactions to severe anaphylaxis. Local reactions may decrease insulin absorption, which may disrupt blood glucose regulation. These reactions may be caused by insulin itself or by its additives. Systemic reactions following insulin injection require allergologic work-up. De- sensitization therapy is a good option for patients with multiple insulin sensitizations

Özet

Sığır ve domuz kaynaklı insülinlerin kullanıldığı dönemlerde nisbeten daha sık görülmekle birlikte günümüzde insan insülini ve insülin analogları ile hipersensitivite reaksiyonlarıyla seyrek olarak karşılaşılmaktadır. Klinik tablo hafif cilt reaksiyonlarından ciddi anafilaksiye kadar değişebilir. Lokal reaksiyonlar insülin absorbsiyonunu azaltarak kan glukoz regülasyonunu bozabilir. Reaksiyonlar insülinin kendisine veya katkı maddelerine bağlı olabilir. İnsülin injeksiyonunun ardından gelişen sistemik reaksiyonlar allergolojik değerlendirme gerektirir. Birçok insülin preparatına allerjisi olan hastalar için desensitizasyon tedavisi uygun bir seçenektir

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Cite This Article

ERDENEN, F., KANTARCI, F. E. N. (2022). Insulin Allergy. İstanbul Medical Journal, Cilt: 17 - Sayı: 3, 77–81. https://ajindex.com/articles/552124

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References (3)

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