Journals / İstanbul Medical Journal / 2021 / Cilt: 22 - Sayı: 3

First Case-Control Study of Intestinal Parasites in Follow-up Schizophrenia Patients: Are We Overlooking the Role of These Agents?

Takip Edilen Şizofreni Hastalarında Barsak Parazitleri Araştırılmasındaki İlk Olgu Kontrol Çalışması: Bu Ajanların Rolünü İnceliyor muyuz?

Pages
213–217
Publication Date
2022-10-19
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Their stool sampleswere examined for the presence of intestinal parasitesprimarily microscopically or serologically in cases requiringdifferential diagnosis.Results: The overall positivity rate of intestinal parasites was25% (15/60).

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: Disability and decrease in the quality of lifeowing to the nature of schizophrenia are considered factors thatpredispose patients to parasitic infections.
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Key Findings & Data:This study aimed toinvestigate intestinal parasites in schizophrenia and healthyvolunteers with similar age-gender data and to contributeto the literature and/or clinical practice by determining theunderlying cause of gastrointestinal complaints (such as sideeffects of psychiatric drugs or overlooked parasitic infection) inpatients with schizophrenia.Methods: This case-control study included 30 patients withschizophrenia and 30 healthy volunteers.
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Conclusion & Impact:Their stool sampleswere examined for the presence of intestinal parasitesprimarily microscopically or serologically in cases requiringdifferential diagnosis.Results: The overall positivity rate of intestinal parasites was25% (15/60).
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: Disability and decrease in the quality of lifeowing to the nature of schizophrenia are considered factors thatpredispose patients to parasitic infections. This study aimed toinvestigate intestinal parasites in schizophrenia and healthyvolunteers with similar age-gender data and to contributeto the literature and/or clinical practice by determining theunderlying cause of gastrointestinal complaints (such as sideeffects of psychiatric drugs or overlooked parasitic infection) inpatients with schizophrenia.Methods: This case-control study included 30 patients withschizophrenia and 30 healthy volunteers. Their stool sampleswere examined for the presence of intestinal parasitesprimarily microscopically or serologically in cases requiringdifferential diagnosis.Results: The overall positivity rate of intestinal parasites was25% (15/60). The difference between the intestinal parasitedetection rates, which was 36.7% (11/30) in the schizophreniagroup and 13.3% (4/30) in the healthy control group, wassignificant (odds ratio: 3.76; 95% confidence interval: 1.04-13.65; p

Özet

Amaç: Şizofreninin doğası gereği gözlenen yetiyitimi ve yaşam kalitesindeki azalma, sekonder olarak paraziter enfeksiyonlara zemin hazırlayan bir faktör olarak değerlendirilmektedir. Bu olgu-kontrol çalışmasına, şizofreni tanısı ile takip edilen hastalar ve yaş-cinsiyet verileri benzer sağlıklı gönüllüler dahil edilerek bu olgu grubundaki barsak parazitlerinin araştırılması amaçlanmıştır. Ayrıca, şizofreni hastalarındaki gastrointestinal şikayetlerin altta yatan nedeni (psikiyatrik ilaç yan etkisi veya gözden kaçırılan paraziter enfeksiyon varlığı) konusunda bilgi sahibi olunarak literatüre ve/veya klinik pratiğe katkı sağlanması amaçlanmıştır. Yöntemler: Çalışmaya 30 şizofreni tanılı hasta ve 30 sağlıklı gönüllü dahil edilmiş, toplamda 60 olgudan dışkı örnekleri alınmış ve bu örneklerdeki bağırsak parazitleri öncelikli olarak mikroskobik ayrıcı tanı gereken durumlarda ise serolojik olarak araştırılmıştır. Bulgular: Çalışmada, barsak parazitlerinin genel pozitiflik oranı %25 (15/60) olarak belirlenmiştir. Şizofreni grubundaki hastalarda %36,7 (11/30), sağlıklı kontrol grubunda %13,3 (4/30) olarak dağılım gösteren barsak paraziti saptanma oranları arasındaki farkın ise istatistiksel olarak anlamlı olduğu belirlenmiştir (olasılık oranı: 3,76; %95 güven aralığı: 1,04- 13,65; p

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Cite This Article

AKGÜL, Ö., ÇALIŞKAN, R., DEMİREL, Ö. F., YALNIZ, Z., SAPMAZ, B., ÖNER, Y. A., BULU, E., KAVLA, Y., POYRAZ, C. A. (2022). First Case-Control Study of Intestinal Parasites in Follow-up Schizophrenia Patients: Are We Overlooking the Role of These Agents?. İstanbul Medical Journal, Cilt: 22 - Sayı: 3, 213–217. https://ajindex.com/articles/551798

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