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Journals / İstanbul Medical Journal / 2022 / Cilt: 23 - Sayı: 1

Effects of Oral Isotretinoin Therapy on Nasal Dryness and Nasal Obstruction in Patients with Acne Vulgaris: Objective and Subjective Assessments Based on the Dose and Duration of Therapy

Zehra ÇINAR
Enes YİĞİT
Duygu ERDİL
Özgür YİĞİT
Efe CAN
Pages
1–5
Publication Date
2022-10-19
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: The right Schirmer values at month 2 (p

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: This study aimed to evaluate the effect of oral isotretinoin therapy on nasal dryness and nasal obstruction in patients with acne vulgaris.
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Key Findings & Data:Methods: A total of 102 patients with acne vulgaris (mean ± standard deviation age, 21.1±3.4 years; female, 64.7%) initiating systemic isotretinoin treatment [in 0.25 mg/kg/day (n=35) or 0.5 mg/kg/day (n=67) doses] were enrolled in this prospective study.
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Conclusion & Impact:Results: The right Schirmer values at month 2 (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: This study aimed to evaluate the effect of oral isotretinoin therapy on nasal dryness and nasal obstruction in patients with acne vulgaris. Methods: A total of 102 patients with acne vulgaris (mean ± standard deviation age, 21.1±3.4 years; female, 64.7%) initiating systemic isotretinoin treatment [in 0.25 mg/kg/day (n=35) or 0.5 mg/kg/day (n=67) doses] were enrolled in this prospective study. Data on nasal obstruction [via nasal obstruction symptom evaluation (NOSE)] and nasal dryness via a psychometric response scale [visual analog scale (VAS)] and nasal Schirmer test values (right and left Schirmer values) were recorded at baseline. Nasal dryness (VAS and nasal Schirmer test) and nasal obstruction (NOSE) assessments were repeated at months 2 and 4 of treatment in isotretinoin groups. Results: The right Schirmer values at month 2 (p

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Cite This Article

ÇINAR, Z., YİĞİT, E., ERDİL, D., YİĞİT, Ö., CAN, E. (2022). Effects of Oral Isotretinoin Therapy on Nasal Dryness and Nasal Obstruction in Patients with Acne Vulgaris: Objective and Subjective Assessments Based on the Dose and Duration of Therapy. İstanbul Medical Journal, Cilt: 23 - Sayı: 1, 1–5. https://ajindex.com/articles/551755

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