Journals / İstanbul Medical Journal / 2020 / Cilt: 21 - Sayı: 4

Can Complete Blood Count Inflammation Markers Be Used to Predict Graft Success After Tympanoplasty?

Timpanoplasti Sonrası Greft Başarısını Ön Görmede Tam Kan Sayımı Enflamasyon Belirteçleri Kullanılabilir mi ?

Pages
307–311
Publication Date
2022-10-19
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Demographic data and routine complete bloodcount parameters, such as NLR, PLR, ELR, BLR and LMR, as wellas intraoperative middle ear characteristics were compared forboth the groups.Results: The following parameters did not differ significantlydiffer (p>0.05) in both groups: age; gender; side; middleear condition; platelet, neutrophil, lymphocyte, eosinophil,monocyte and basophil counts; NLR; PLR; ELR; BLR and LMR.Conclusion: From the results, it can be concluded that NLR,PLR, ELR, BLR and LMR, which are markers of inflammationin the preoperative period, cannot be used to predict graftsuccess in patients who will undergo tympanoplasty for chronicotitis media.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: This study aimed to investigate the effect ofpreoperative neutrophil lymphocyte ratio (NLR), plateletlymphocyte ratio (PLR), eosinophil lymphocyte ratio (ELR),basophil lymphocyte ratio (BLR) and lymphocyte monocyteratio (LMR) on graft success after tympanoplasty.Methods: Forty-five patients who underwent tympanoplastywith temporal fascia graft between January 2017 andDecember 2019 were included in this study.
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Key Findings & Data:The patientswere divided into two groups: intact (13 men, 12 women) andperforated (13 women, 7 men) according to their postoperativegraft results.
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Conclusion & Impact:Demographic data and routine complete bloodcount parameters, such as NLR, PLR, ELR, BLR and LMR, as wellas intraoperative middle ear characteristics were compared forboth the groups.Results: The following parameters did not differ significantlydiffer (p>0.05) in both groups: age; gender; side; middleear condition; platelet, neutrophil, lymphocyte, eosinophil,monocyte and basophil counts; NLR; PLR; ELR; BLR and LMR.Conclusion: From the results, it can be concluded that NLR,PLR, ELR, BLR and LMR, which are markers of inflammationin the preoperative period, cannot be used to predict graftsuccess in patients who will undergo tympanoplasty for chronicotitis media.
🔬Design:Research Article
📍Scope:2017 Verileri
⚙️Variables:Domain Parameters

Abstract

Introduction: This study aimed to investigate the effect ofpreoperative neutrophil lymphocyte ratio (NLR), plateletlymphocyte ratio (PLR), eosinophil lymphocyte ratio (ELR),basophil lymphocyte ratio (BLR) and lymphocyte monocyteratio (LMR) on graft success after tympanoplasty.Methods: Forty-five patients who underwent tympanoplastywith temporal fascia graft between January 2017 andDecember 2019 were included in this study. The patientswere divided into two groups: intact (13 men, 12 women) andperforated (13 women, 7 men) according to their postoperativegraft results. Demographic data and routine complete bloodcount parameters, such as NLR, PLR, ELR, BLR and LMR, as wellas intraoperative middle ear characteristics were compared forboth the groups.Results: The following parameters did not differ significantlydiffer (p>0.05) in both groups: age; gender; side; middleear condition; platelet, neutrophil, lymphocyte, eosinophil,monocyte and basophil counts; NLR; PLR; ELR; BLR and LMR.Conclusion: From the results, it can be concluded that NLR,PLR, ELR, BLR and LMR, which are markers of inflammationin the preoperative period, cannot be used to predict graftsuccess in patients who will undergo tympanoplasty for chronicotitis media.

Özet

Amaç: Bu çalışmanın amacı preoperatif nötrofil lenfosit oranı (NLO), platelet lenfosit oranı (PLO), eozinofil lenfosit oranı (ELO), bazofil lenfosit oranı (BLO) ve lenfosit monosit oranı (LMO)’nın temporal fasya grefti kullanılan timpanoplasti öncesi greft başarısını ön görmede kullanılabilirliğini ortaya koymaktır. Yöntemler: Ocak 2017-Aralık 2019 tarihleri arasında kliniğimizde kronik otitis media nedeniyle temporal fasya grefti ile timpanoplasti yapılan hastalar grefti başarılı olan intakt grup (13 erkek,12 kadın) ve grefti başarız olan perfore grup (13 kadın, 7 erkek) olmak üzere iki gruba ayrıldı. Bu iki grup yaş, taraf ve cinsiyet ile tam kan sayımında hücre sayıları ve NLO, PLO, ELO, BLO ve LMO ve orta kulağın durumu açısından karşılaştırıldı. Bulgular: İntakt ve perfore gruplarda yaş, cinsiyet dağılımı, taraf ve orta kulağın durumu ile platelet, nötrofil, lenfosit, eozinofil, monosit, bazofil sayıları ve NLO, PLO, ELO, BLO ve LMO anlamlı (p>0,05) farklılık göstermemiştir. Sonuç: Bu çalışmanın bulguları ışığında kronik otitis medya nedeniyle timpanoplasti uygulanacak hastalarda preoperatif dönem enflamasyon belirteçleri olan NLO, PLO, ELO, BLO ve LMO’nun greft başarısını ön görmede kullanılamayacğı sonucuna varılmıştır.

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Cite This Article

SÜNTER, A. V., YİĞİT, Ö., ÇINAR, Z. (2022). Can Complete Blood Count Inflammation Markers Be Used to Predict Graft Success After Tympanoplasty?. İstanbul Medical Journal, Cilt: 21 - Sayı: 4, 307–311. https://ajindex.com/articles/551835

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