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Journals / İstanbul Medical Journal / 2021 / Cilt: 22 - Sayı: 2

C-Reactive Protein and Albumin Ratio Predicts Mortality in Elderly Patients Aged Eighty Years and Over with Non-STSegment Elevation Myocardial Infarction

C-Reaktif Protein/Albümin Oranı ST-Segment Yükselmesiz Miyokart Enfarktüsü Olan Seksen Yaş ve Üzerindeki Yaşlı Hastalarda Mortaliteyi Öngörür

Tufan ÇINAR
Can Yücel KARABAY
Barış ŞİMŞEK
Kazım Serhan ÖZCAN
Veysel Ozan TANIK
Barış GÜNGÖR
Duygu İNAN
Gönül ZEREN
İlhan İlker AVCI
Mustafa Azmi SUNGUR
Pages
88–93
Publication Date
2022-10-19
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Cases included in the T3tertile had significantly higher incidence of cardiopulmonaryarrest, cardiac mortality, and all-cause mortality duringthe index hospitalization [(15% vs 4% vs 0.5%), (10% vs 1%vs 0%), and (13% vs 2% vs 0%), respectively, p1on admission, revascularization, and CAR (odds ratio: 1.47, 95%confidence intervals: 1.23-1.75, p1.12 predicted in-hospital mortality with a sensitivity of 85%and specificity of 77% (area under the curve: 0.813, p

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: To explore the prognostic importance foradmission of C-reactive protein (CRP)/albumin ratio (CAR) inelderly patients aged 80 years over who presented with non-STelevation myocardial infarction (non-STEMI).Methods: This retrospective, observational research wasrelated to the clinical data of 528 elderly non-STEMI patients.The study population was categorized based on CAR tertiles asT1, T2, and T3 groups.
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Key Findings & Data:The main outcome of the research was thein-hospital mortality.Results: The in-hospital mortality rate during indexhospitalization was 5% (n=27 patients).
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Conclusion & Impact:Cases included in the T3tertile had significantly higher incidence of cardiopulmonaryarrest, cardiac mortality, and all-cause mortality duringthe index hospitalization [(15% vs 4% vs 0.5%), (10% vs 1%vs 0%), and (13% vs 2% vs 0%), respectively, p1on admission, revascularization, and CAR (odds ratio: 1.47, 95%confidence intervals: 1.23-1.75, p1.12 predicted in-hospital mortality with a sensitivity of 85%and specificity of 77% (area under the curve: 0.813, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: To explore the prognostic importance foradmission of C-reactive protein (CRP)/albumin ratio (CAR) inelderly patients aged 80 years over who presented with non-STelevation myocardial infarction (non-STEMI).Methods: This retrospective, observational research wasrelated to the clinical data of 528 elderly non-STEMI patients.The study population was categorized based on CAR tertiles asT1, T2, and T3 groups. The CAR was obtained by dividing CRPto albumin level. The main outcome of the research was thein-hospital mortality.Results: The in-hospital mortality rate during indexhospitalization was 5% (n=27 patients). Cases included in the T3tertile had significantly higher incidence of cardiopulmonaryarrest, cardiac mortality, and all-cause mortality duringthe index hospitalization [(15% vs 4% vs 0.5%), (10% vs 1%vs 0%), and (13% vs 2% vs 0%), respectively, p1on admission, revascularization, and CAR (odds ratio: 1.47, 95%confidence intervals: 1.23-1.75, p1.12 predicted in-hospital mortality with a sensitivity of 85%and specificity of 77% (area under the curve: 0.813, p

Özet

Amaç: ST-segment yükselmesi olmayan miyokard enfarktüs (non-STYOME) ile başvuran 80 yaş üstü yaşlı hastalarda başvuru C-reaktif protein (CRP)/albümin oranının (CAO) prognostik önemini araştırmaktır. Yöntemler: Bu geriye dönük, gözlemsel çalışma, STYOME’li 528 yaşlı hastanın klinik verileriyle ilgiliydi. Çalışma popülasyonu, CAO tertillerine göre T1, T2 ve T3 grupları olarak kategorize edildi. CAO’yu, CRP’nin albümin düzeyine bölünmesiyle elde edildi. Çalışmanın birincil ana sonlanımı, hastane içi mortaliteydi. Bulgular: İndeks hastaneye yatışta, mortalite %5 (n=27 hasta) idi. T3 grubuna dahil edilen hastalarda, kardiyopulmoner arrest, kardiyak mortalite ve tüm nedenlere bağlı mortalite hastanede yatış sırasında önemli ölçüde daha yüksek saptandı [(%15 vs %4 vs %0,5), (%10 vs %1 vs %0) ve (%13 vs %2 vs %0), sırasıyla, her biri için p1, revaskülarizasyon ve CAO (olasılık oranı: 1,47, 95% güven aralığı: 1,23-1,75, p1,12’nin %85 duyarlılık ve %77 özgüllük ile hastane içi mortaliteyi öngördüğünü ortaya koydu (eğri altındaki alan: 0,813, p

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Cite This Article

ÇINAR, T., KARABAY, C. Y., ŞİMŞEK, B., ÖZCAN, K. S., TANIK, V. O., GÜNGÖR, B., İNAN, D., ZEREN, G., AVCI, İ. İ., SUNGUR, M. A. (2022). C-Reactive Protein and Albumin Ratio Predicts Mortality in Elderly Patients Aged Eighty Years and Over with Non-STSegment Elevation Myocardial Infarction. İstanbul Medical Journal, Cilt: 22 - Sayı: 2, 88–93. https://ajindex.com/articles/551657

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