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Journals / İstanbul Kuzey Klinikleri / 2017 / Cilt: 4 - Sayı: 1

Increased levels of red cell distribution width is correlated with presence of left atrial stasis in patients with non-valvular atrial fibrillation

Adnan KAYA
Fatma Ozpamuk KARADENİZ
Baris GUNGOR
Osman KAYAPİNAR
Ceyhan TUKKAN
Gulay GOK
Kazim Serhan OZCAN
Mustafa Adem TATLİSU
Ahmet Ilker TEKKESİN
Ahmet Taha ALPER
Pages
66–72
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

LAS (+) group, values for RDW (14.85±1.48 vs. 13.77±1.30; p

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: Red cell distribution width (RDW) and neutrophil to lymphocyte ratio (NLR) have been found to be associated with non-valvular atrial fibrillation (AF) and cardiovascular diseases.
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Key Findings & Data:This study was an investigation of correlation of RDW, NLR, and clinical risk factors with LA thrombus and dense SEC in patients with non-valvular AF in the Turkish population.METHODS: The demographic, laboratory, and echocardiographic properties of 619 non-valvular AF patients who underwent transesophageal echocardiography (TEE) examination before direct current cardioversion (DCCV) or AF ablation treatment were retrospectively investigated.
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Conclusion & Impact:LAS (+) group, values for RDW (14.85±1.48 vs. 13.77±1.30; p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: Red cell distribution width (RDW) and neutrophil to lymphocyte ratio (NLR) have been found to be associated with non-valvular atrial fibrillation (AF) and cardiovascular diseases. However, correlation of these parameters with presence of left atrial (LA) thrombus and/or spontaneous echo contrast (SEC) in patients with non-valvular AF has not been clarified. This study was an investigation of correlation of RDW, NLR, and clinical risk factors with LA thrombus and dense SEC in patients with non-valvular AF in the Turkish population.METHODS: The demographic, laboratory, and echocardiographic properties of 619 non-valvular AF patients who underwent transesophageal echocardiography (TEE) examination before direct current cardioversion (DCCV) or AF ablation treatment were retrospectively investigated. Complete blood count (CBC) and biochemical parameters were studied 6 to 12 hours before TEE examination. Left atrial stasis (LAS) markers were noted as presence of left atrial/left atrial appendage (LA/LAA) thrombus or dense spontaneous echo contrast (DSEC).RESULTS: Total of 325 (52%) patients with LAS were compared with 294 patients (48%) without LAS. In the LAS group, there were 274 (84%) patients with LA/LAA thrombus and 51 (16%) patients with DSEC. LAS (+) group, values for RDW (14.85±1.48 vs. 13.77±1.30; p

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Cite This Article

KAYA, A., KARADENİZ, F. O., GUNGOR, B., KAYAPİNAR, O., TUKKAN, C., GOK, G., OZCAN, K. S., TATLİSU, M. A., TEKKESİN, A. I., ALPER, A. T. (2022). Increased levels of red cell distribution width is correlated with presence of left atrial stasis in patients with non-valvular atrial fibrillation. İstanbul Kuzey Klinikleri, Cilt: 4 - Sayı: 1, 66–72. https://ajindex.com/articles/551575

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References (12)

  1. Morady F, Zipes DP. Atrial fibrillation: clinical features, mechanisms and management. In: Braunwald E, Libby P, Bonow RO, Mann DL, Zipes DP, editors. Braunwald's heart disease. A textbook of cardiovascular medicine. 9th ed. Philadelphia, PA: WB Saunders Company; 2012. p. 825-84
  2. Khoo CW, Krishnamoorthy S, Lim HS, Lip GY. Atrial fibrillation, arrhythmia burden and thrombogenesis. Int J Cardiol 2012;157:318-23
  3. Watson T, Shantsila E, Lip GY. Mechanisms of thrombogenesis in atrial fibrillation: Virchow's triad revisited. Lancet 2009;373:155-66
  4. Lappé JM, Horne BD, Shah SH, May HT, Muhlestein JB, Lappé DL, et al. Red cell distribution width, C-reactive protein, the complete blood count, and mortality in patients with coronary disease and a normal comparison population. Clin Chim Acta 2011;412:2094-9
  5. Felker GM, Allen LA, Pocock SJ, Shaw LK, McMurray JJ, Pfeffer MA, et al; CHARM Investigators. Red cell distribution width as a novel prognostic marker in heart failure: data from the CHARM Program and the Duke Databank. J Am Coll Cardiol 2007;50:40-7
  6. Tonelli M, Sacks F, Arnold M, Moye L, Davis B, Pfeffer M; for the Cholesterol and Recurrent Events (CARE) Trial Investigators. Relation Between Red Blood Cell Distribution Width and Cardiovascular Event Rate in People With Coronary Disease. Circulation 2008;117:163-8
  7. Klein AL, Grimm RA, Murray RD, Apperson-Hansen C, Asinger RW, Black IW, et al; Assessment of Cardioversion Using Transesophageal Echocardiography Investigators. Use of transesophageal echocardiography to guide cardioversion in patients with atrial fibrillation. N Engl J Med 2001;344:1411-20
  8. Scherr D, Dalal D, Chilukuri K, Dong J, Spragg D, Henrikson CA, et al. Incidence and predictors of left atrial thrombus prior to catheter ablation of atrial fibrillation. J Cardiovasc Electrophysiol 2009;20:379-84
  9. Kerut EK, Hanawalt C, McKinnie J. Transesophageal echocardiography during pulmonary vein cryoballoon ablation for atrial fibrillation. Echocardiography 2015;32:281-90
  10. Fatkin D, Loupas T, Jacobs N, Feneley MP. Quantification of blood echogenicity: evaluation of a semiquantitative method of grading spontaneous echo contrast. Ultrasound Med Biol 1995;21:1191-8
  11. Olesen JB, Lip GY, Hansen ML, Hansen PR, Tolstrup JS, Lindhardsen J, et al. Validation of risk stratification schemes for predicting stroke and thromboembolism in patients with atrial fibrillation: nationwide cohort study. BMJ 2011;342:d124
  12. Griffin BP. Manual