Thus, we made an evaluation of hs-cTnT analysis in noncoronary patients, which may contribute to the literature.
📌 3 Key Takeaways
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Objective & Hypothesis:Cardiac troponin is the preferred biomarker for the diagnosis of the acute coronary syndrome (ACS), but many other diseasescan be identified with elevated troponin levels in the absence of ACS.
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Key Findings & Data:The recent development of a high-sensitive cardiac troponin T (hs-cTnT) assay permits the detection of very low levels of cTnT.
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Conclusion & Impact:Thus, we made an evaluation of hs-cTnT analysis in noncoronary patients, which may contribute to the literature.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
Cardiac troponin is the preferred biomarker for the diagnosis of the acute coronary syndrome (ACS), but many other diseasescan be identified with elevated troponin levels in the absence of ACS. The recent development of a high-sensitive cardiac troponin T (hs-cTnT) assay permits the detection of very low levels of cTnT. The use of hs-cTnT assay has emerged as a tool foridentifying high-risk individuals for primary preventive treatment and can detect subclinical injury in asymptomatic patients.Hs-cTnT analyses are generally related to ischemia in the literature. Thus, we made an evaluation of hs-cTnT analysis in noncoronary patients, which may contribute to the literature.
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Cite This Article
TANRIVERDİ, O., AŞKIN, L., TÜRKMEN, S. (2022). Clinical importance of high- sensitivity troponin T in patients without coronary artery disease. İstanbul Kuzey Klinikleri, Cilt: 7 - Sayı: 3, 305–310. https://ajindex.com/articles/551378
Dubin RF, Li Y, He J, Jaar BG, Kallem R, Lash JP, et al; CRIC Study Investigators. Predictors of high sensitivity cardiac troponin T in chronic kidney disease patients: a cross-sectional study in the chronic renal insufficiency cohort (CRIC). BMC Nephrol 2013;14:229
Wu W, Li DX, Wang Q, Xu Y, Cui YJ. Relationship between high-sensitivity cardiac troponin T and the prognosis of elderly inpatients with non-acute coronary syndromes. Clin Interv Aging 2018;13:1091–8
Thygesen K, Mair J, Mueller C, Huber K, Weber M, Plebani M, et al; Study Group on Biomarkers in Cardiology of the ESC Working Group on Acute Cardiac Care. Recommendations for the use of natriuretic peptides in acute cardiac care: a position statement from the Study Group on Biomarkers in Cardiology of the ESC Working Group on Acute Cardiac Care. Eur Heart J 2012;33:2001–6
Vasile VC, Saenger AK, Kroning JM, Jaffe AS. Biological and analytical variability of a novel high-sensitivity cardiac troponin T assay. Clin Chem 2010;56:1086–90
Cardinaels EP, Daamen MA, Bekers O, ten Kate J, Niens M, van Suijlen JD, et al. Clinical Interpretation of Elevated Concentrations of Cardiac Troponin T, but Not Troponin I, in Nursing Home Residents. J Am Med Dir Assoc 2015;16:884–91. 6. de Lemos JA, Drazner MH, Omland T, Ayers CR, Khera A, Rohatgi A, et al. Association of troponin T detected with a highly sensitive assay and cardiac structure and mortality risk in the general population. JAMA 2010;304:2503–12
Macedo ME, Lima MJ, Silva AO, Alcantara P, Ramalhinho V, Carmona J. Prevalence, awareness, treatment and control of hypertension in Portugal: the PAP study. J Hypertens 2005;23:1661–6
Melander O, Newton-Cheh C, Almgren P, Hedblad B, Berglund G, Engström G, et al. Novel and conventional biomarkers for prediction of incident cardiovascular events in the community. JAMA 2009;302:49– 57
Selvin E, Lazo M, Chen Y, Shen L, Rubin J, McEvoy JW, et al. Diabetes mellitus, prediabetes, and incidence of subclinical myocardial damage. Circulation 2014;130:1374–82
Çaylı M, Gür M, Elbasan Z, Şeker T, Türkoğlu C, Kaypaklı O, et al. High-sensitivity cardiac troponin T predicts nondipper hypertension in newly diagnosed hypertensive patients. J Clin Hypertens (Greenwich) 2013;15:731–6
Sato Y, Yamamoto E, Sawa T, Toda K, Hara T, Iwasaki T, et al. Highsensitivity cardiac troponin T in essential hypertension. J Cardiol 2011;58:226–31
Saunders JT, Nambi V, de Lemos JA, Chambless LE, Virani SS