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Journals / İstanbul Kuzey Klinikleri / 2020 / Cilt: 7 - Sayı: 1

An investigation into hemodynamically significant coronary artery lesions predictors assessed by fractional flow reserve: A propensity score matching analysis

Oktay GÜLCÜ
Selim TOPÇU
Uğur AKSU
Kamuran KALKAN
Selami DEMİRELLİ
Emrah AKSAKAL
Pages
35–39
Publication Date
2022-10-18
DOI
—
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In univariate analysis, after PSM analysis, Diameter stenosis (DS) and proximal LAD lesion (PLL) were associated with lower FFR values.CONCLUSION: This study indicated that the majority of traditional FFR predictors did not reach the limit of significance afterPSM analysis and we suggest that DS and PLL are one step ahead of predicting lesion severity compared to other traditionalrisk factors.

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Objective & Hypothesis:OBJECTIVE: Fractional flow reserve (FFR) provides more useful information regarding myocardial metabolism and demandsupply convenience as compared to anatomical measurements.
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Key Findings & Data:In this study, we aimed to investigate FFR predictors afterpropensity score matching (PSM) analysis in patients with intermediate coronary lesions.METHODS: Patients who underwent coronary angiography between January 2014 and March 2015 due to suspicion ofcoronary artery disease were included in this study.
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Conclusion & Impact:In univariate analysis, after PSM analysis, Diameter stenosis (DS) and proximal LAD lesion (PLL) were associated with lower FFR values.CONCLUSION: This study indicated that the majority of traditional FFR predictors did not reach the limit of significance afterPSM analysis and we suggest that DS and PLL are one step ahead of predicting lesion severity compared to other traditionalrisk factors.
🔬Design:Research Article
📍Scope:2014 Verileri
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: Fractional flow reserve (FFR) provides more useful information regarding myocardial metabolism and demandsupply convenience as compared to anatomical measurements. In this study, we aimed to investigate FFR predictors afterpropensity score matching (PSM) analysis in patients with intermediate coronary lesions.METHODS: Patients who underwent coronary angiography between January 2014 and March 2015 due to suspicion ofcoronary artery disease were included in this study. Patients were divided into two groups according to the FFR status andpredictors of FFR before and after PSM analysis were investigated.RESULTS: A total of 290 patients (a total of 310 lesions) were included in this study (61±12 years, 75.5% male). In univariate analysis, after PSM analysis, Diameter stenosis (DS) and proximal LAD lesion (PLL) were associated with lower FFR values.CONCLUSION: This study indicated that the majority of traditional FFR predictors did not reach the limit of significance afterPSM analysis and we suggest that DS and PLL are one step ahead of predicting lesion severity compared to other traditionalrisk factors.

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Cite This Article

GÜLCÜ, O., TOPÇU, S., AKSU, U., KALKAN, K., DEMİRELLİ, S., AKSAKAL, E. (2022). An investigation into hemodynamically significant coronary artery lesions predictors assessed by fractional flow reserve: A propensity score matching analysis. İstanbul Kuzey Klinikleri, Cilt: 7 - Sayı: 1, 35–39. https://ajindex.com/articles/551367

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