Journals / Annals of Medical Research / 2019 / Cilt: 26 - Sayı: 7

The association between neutrophil to lymphocyte ratio and contrast induced nephropathy in patients with ST segment elevation myocardial infarction

Pages
1184–1188
Publication Date
2022-10-12
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

In multivariate analysis, NLR (OR: 0.92, 95% CI: 0.86-0.98and p: 0,022) and Lesion length (OR: 0.88, 95% CI: 0.79-0.98 and p: 0,029)and were associated with CIN development.Conclusions: In this study, we showed that lesion length and NLR were independent predictors of CIN and we proposed thatinflammatory process could play key role in CIN development when compared to traditional risk factors.

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Objective & Hypothesis:Aim: The increase in the number of percutaneous coronary interventions(PCI) has also led to an increase in risk associatedwith intervention-including radiation injury, contrast-induced nephropathy (CIN), risk of stroke, and vascular complications.
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Key Findings & Data:In this study we aimed to investigate the associationbetween inflammatory parameters and CIN development in patients with ST segment elevation myocardial infarction (STEMI).Material and Methods: Patients who underwent coronary angiography with STEMI diagnosis between January 2015 and March 2018were included in the study.
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Conclusion & Impact:In multivariate analysis, NLR (OR: 0.92, 95% CI: 0.86-0.98and p: 0,022) and Lesion length (OR: 0.88, 95% CI: 0.79-0.98 and p: 0,029)and were associated with CIN development.Conclusions: In this study, we showed that lesion length and NLR were independent predictors of CIN and we proposed thatinflammatory process could play key role in CIN development when compared to traditional risk factors.
🔬Design:Research Article
📍Scope:2015 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: The increase in the number of percutaneous coronary interventions(PCI) has also led to an increase in risk associatedwith intervention-including radiation injury, contrast-induced nephropathy (CIN), risk of stroke, and vascular complications. Thedevelopment of CIN is an important clinical situation in patients undergoing PCI. In this study we aimed to investigate the associationbetween inflammatory parameters and CIN development in patients with ST segment elevation myocardial infarction (STEMI).Material and Methods: Patients who underwent coronary angiography with STEMI diagnosis between January 2015 and March 2018were included in the study. Two groups were formed according to the CIN status and predictors of CIN were investigated.Results: The average age of the patients is 58±12 years and 78.2% males. In multivariate analysis, NLR (OR: 0.92, 95% CI: 0.86-0.98and p: 0,022) and Lesion length (OR: 0.88, 95% CI: 0.79-0.98 and p: 0,029)and were associated with CIN development.Conclusions: In this study, we showed that lesion length and NLR were independent predictors of CIN and we proposed thatinflammatory process could play key role in CIN development when compared to traditional risk factors.

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Cite This Article

GÜLCÜ, O. (2022). The association between neutrophil to lymphocyte ratio and contrast induced nephropathy in patients with ST segment elevation myocardial infarction. Annals of Medical Research, Cilt: 26 - Sayı: 7, 1184–1188. https://ajindex.com/articles/446828

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References (12)

  1. Kolh P, Windecker S, Alfonso F, et al. 2014 ESC/EACTS Guidelines on myocardial revascularization: the task force on myocardial revascularization of the european society of cardiology (esc) and the european association for cardio-thoracic surgery (eacts). developed with the special contribution of the european association of percutaneous cardiovascular interventions (eapci). Eur J Cardiothorac Surg 2014;46:517-92
  2. Witberg G, Kornowski R. Current perspectives on revascularization in multivessel ST elevation myocardial infarction. Coron Artery Dis 2017;28:498-506
  3. Levine GN, Bates ER, Blankenship JC, et al. 2015 ACC/AHA/ SCAI focused update on primary percutaneous coronary intervention for patients with st-elevation myocardial infarction: an update of the 2011 accf/aha/scai guideline for percutaneous coronary intervention and the 2013 accf/aha guideline for the management of st-elevation myocardial infarction: a report of the american college of cardiology/ american heart association task force on clinical practice guidelines and the society for cardiovascular angiography and interventions. Circulation 2016;133:1135-47
  4. Reed GW, Rossi JE, Cannon CP. Acute myocardial infarction. Lancet 2016;389:197-210
  5. Honicker T, Holt K. Contrast-Induced Acute Kidney Injury: Comparison of Preventative Therapies. Nephrol Nurs J 2016;43:109-16
  6. Ando G, Trio O. Contrast-Induced Nephropathy After Primary Percutaneous Coronary Intervention: The Need for a Unifying Definition. Am J Cardiol. 2017;119:169
  7. Rosenbaum PR, Rubin DB. Difficulties with regression analyses of age-adjusted rates. Biometrics 1984;40:437- 43
  8. Baek S, Park SH, Won E, et al. Propensity score matching: a conceptual review for radiology researchers. Korean J Radiol 2015;16:286-96
  9. Filleron T, Kwiatowski F. [Propensity score: A credible alternative to randomization?]. Bull Cancer 2016;103:113- 22
  10. McMurry TL, Hu Y, Blackstone EH, et al. Propensity scores: Methods, considerations, and applications in the Journal of Thoracic and Cardiovascular Surgery. J Thorac Cardiovasc Surg 2015;150:14-9
  11. ACT Investigators. Acetylcysteine for prevention of renal outcomes in patients undergoing coronary and peripheral vascular angiography: main results from the randomized Acetylcysteine for Contrast-induced nephropathy Trial (ACT). Circulation 2011;124:1250-9
  12. Sianos G, Morel MA, Kappetein AP, et al. The SYNTAX Score: an angiographic tool grading the complexity of coronary artery disease. Eu