AI Summary & Key Takeaways
AI InsightMore studies are required to form aconsensus regarding how hyperventilation applies to ECT.
📌 3 Key Takeaways
Abstract
OBJECTIVE: Previous studies have reported that hyperventilation prolongs seizure length. However, there is no clear consensus in clinical guidelines on how to perform hyperventilation during Electroconvulsive Therapy (ECT). The present studyaims to investigate the effects of hyperventilation on seizure length and cerebral oxygenation.METHODS: Forty patients aged 18–65 and classified as ASA I-II, who would have their first ECT course were included in thestudy. Ethics committee approval was obtained and all patients’ consent was taken. The consecutive patients were randomized into two groups as follows: group H (20 patients; target etCO2: 25–30 mmHg) and group N (20 patients; target etCO235–40 mmHg). All patients were ventilated with a facial mask for two minutes and later were ventilated by a laryngeal mask(LMA) for one minute. Vital signs, peripheric oxygen saturation (SpO2), and regional oxygen saturation (rSO2) were measuredbefore general anesthesia induction, on the 3rd minute of ventilation with an LMA (LMA3), on the 1st minute postictal (PI1), onthe 5th (PI5), and 10th (PI10) minutes. The motor seizure duration, Richmond sedation-agitation scale, and the time needed toreach Aldrete Score 9 were also recorded.RESULTS: There was a significant difference between the groups when they were compared concerning seizure length andrecovery time. However, when we compared the rSO2 values that were measured at different times in group H, the differencebetween the measurements was statistically significant. When rSO2 values in group H were compared in doubles, there weresignificant differences between measurements between the basal and LMA3, basal and PI1, and the basal and PI5. When Richmond agitation scores in both groups are compared, there were no significant differences between the groups.CONCLUSION: This study found that seizure length was longer, and the recovery time was shorter in group H. There was acontribution of hyperventilation on cerebral oxygenation that was measured on the same person at different times, but cerebral oxygenation was not statistically different from patients that were normoventilated. More studies are required to form aconsensus regarding how hyperventilation applies to ECT.