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Journals / İstanbul Kuzey Klinikleri / 2021 / Cilt: 8 - Sayı: 2

The evaluation of relationship betweenpolypharmacy and anticholinergic burden scales

Pinar SOYSAL
Ahmet Turan ISIK
Suleyman Emre KOÇYİĞİT
Saadet Koc OKUDUR
Özge DOKUZLAR
Ali Ekrem AYDIN
Pages
139–144
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The highest relationship with polypharmacy was observed for drug burden index (DBI) (odds ratio 10.87, p

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: Polypharmacy and anticholinergic burden are the indicators for the evaluation of the quality of pharmacotherapy in older adults.
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Key Findings & Data:Anticholinergic burden scales were calculated by a tool named anticholinergic burden calculator.RESULTS: The participants’ mean age was 73.08±8.71.
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Conclusion & Impact:The highest relationship with polypharmacy was observed for drug burden index (DBI) (odds ratio 10.87, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: Polypharmacy and anticholinergic burden are the indicators for the evaluation of the quality of pharmacotherapy in older adults. The aim of this study was to consider which anticholinergic burden scales are more related with polypharmacy among older patients.METHODS: Four hundred and twenty older adults were evaluated retrospectively in this cross-sectional study. The patient’s demographic data, comorbidities, the drugs, and number of drugs were recorded. Anticholinergic burden scales were calculated by a tool named anticholinergic burden calculator.RESULTS: The participants’ mean age was 73.08±8.71. The prevalence of polypharmacy was 32.14%. The highest relationship with polypharmacy was observed for drug burden index (DBI) (odds ratio 10.87, p

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Cite This Article

SOYSAL, P., ISIK, A. T., KOÇYİĞİT, S. E., OKUDUR, S. K., DOKUZLAR, Ö., AYDIN, A. E. (2022). The evaluation of relationship betweenpolypharmacy and anticholinergic burden scales. İstanbul Kuzey Klinikleri, Cilt: 8 - Sayı: 2, 139–144. https://ajindex.com/articles/551321

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References (12)

  1. United Nations. World population prospects. 2017 revision. Available at: https://population.un.org/wpp/Publications/Files/WPP2017_ KeyFindings.pdf. Accessed Feb 12, 2021
  2. Ates Bulut E, Soysal P, Isik AT. Frequency and coincidence of geriatric syndromes according to age groups: single-center experience in Turkey between 2013 and 2017. Clin Interv Aging 2018;13:1899–905
  3. Jyrkkä J, Enlund H, Korhonen MJ, Sulkava R, Hartikainen S. Patterns of drug use and factors associated with polypharmacy and excessive polypharmacy in elderly persons: results of the Kuopio 75+ study: a cross-sectional analysis. Drugs Aging 2009;26:493–503
  4. Fick DM, Cooper JW, Wade WE, Waller JL, Maclean JR, Beers MH. Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. Arch Intern Med 2003;163:2716–24
  5. American Geriatrics Society 2012 Beers Criteria Update Expert Panel. American Geriatrics Society updated Beers Criteria for potentially inappropriate medication use in older adults. J Am Geriatr Soc 2012;60:616–31
  6. Rudd KM, Raehl CL, Bond CA, Abbruscato TJ, Stenhouse AC. Methods for assessing drug-related anticholinergic activity. Pharmacotherapy 2005;25:1592–601
  7. Wilson M, Mair A, Dreischulte T, Witham MD; NHS Scotland Model of Care Polypharmacy Working Group. Prescribing to fit the needs of older people-the NHS Scotland Polypharmacy Guidance, 2nd edition. J R Coll Physicians Edinb 2015;45:108–13
  8. Onder G, Landi F, Fusco D, Corsonello A, Tosato M, Battaglia M, et al. Recommendations to prescribe in complex older adults: results of the CRIteria to assess appropriate Medication use among Elderly complex patients (CRIME) project. Drugs Aging 2014;31:33–45
  9. Salahudeen MS, Hilmer SN, Nishtala PS. Comparison of anticholinergic risk scales and associations with adverse health outcomes in older people. J Am Geriatr Soc 2015;63:85–90
  10. Cancelli I, Beltrame M, Gigli GL, Valente M. Drugs with anticholinergic properties: cognitive and neuropsychiatric side-effects in elderly patients. Neurol Sci 2009;30:87–92
  11. Fox C, Smith T, Maidment I, Chan WY, Bua N, Myint PK, et al. Effect of medications with anti-cholinergic properties on cognitive function, delirium, physical function and mortality: a systematic review. Age Ageing 2014;43:604–15
  12. Kumpula EK, Bell JS, Soini H, Pitkälä KH. Anticholinergic drug use and mortality among residents of long-term care facilities: a prospective cohort