Journals / İstanbul Kanuni Sultan Süleyman Tıp Dergisi / 2018 / Cilt: 10 - Sayı: 3

Effect of Diastolic Heart Dysfunction Due to Hypertrophic Cardiomyopathy on Choroidal Thickness

Hipertrofik Kardiyomyopatiye Bağlı Diyastolik Kalp Disfonksiyonun, Koroid Kalınlığı Üzerine Etkisi

Pages
143–148
Publication Date
2022-10-18
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: No change in choroidal thickness in patients with diastolic dysfunction suggesting that there is no significant decrease in blood flow in the posterior ciliary arteries in diastolic heart dysfunction.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: To investigate choroidal thickness change in patients with diastolic dysfunction secondary to hypertrophic cardiomyopathy (HCM).
📊
Key Findings & Data:Material and Method: Sixty- five eyes of 33 patients with diagnosis of HCM and 65 eyes of 33 healthy subjects were included in the cross-sectional, case-controlled, prospective study.
💡
Conclusion & Impact:Conclusion: No change in choroidal thickness in patients with diastolic dysfunction suggesting that there is no significant decrease in blood flow in the posterior ciliary arteries in diastolic heart dysfunction.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: To investigate choroidal thickness change in patients with diastolic dysfunction secondary to hypertrophic cardiomyopathy (HCM). Material and Method: Sixty- five eyes of 33 patients with diagnosis of HCM and 65 eyes of 33 healthy subjects were included in the cross-sectional, case-controlled, prospective study. The retina nerve fiber layer (RNFL) thickness, macular thickness, macular volume, ganglion cell thickness, subfoveal choroidal thickness (SFCT), choroidal thickness of 1 mm nasal side of fovea (NCT), choroidal thickness of 1 mm temporal side of fovea (TCT) were compared between the two groups with Spectral Domain Zeiss Cirrus device. Results: In the HCM group, 11 of 33 patients were female and 22 were male. In the control group, 10 of the 33 patients were female and 23 were male. There was no difference between the two groups in terms of age, body mass index, spherical equivalent, axial length, and intraocular pressure that might affect choroidal thickness. SFCT was measured as 266.3± 50.1 µm in the HCM group and 273.6±56.8 µm in the control group. NCT was measured as 262±55.9 µm in the HCM group and 261.2±41.4 µm in the control group. TCT was measured 270.5±57.5 µm in the HCM group and 259.4±52.7 µm in the control group. RNFL, macular thickness, macular volume, SFCT, NCT, TCT values were not statistically different between the two groups. Conclusion: No change in choroidal thickness in patients with diastolic dysfunction suggesting that there is no significant decrease in blood flow in the posterior ciliary arteries in diastolic heart dysfunction.

Özet

Amaç: Diyastolik disfonksiyon gelişmiş hipertrofik kardiyomyopatili (HKM) hastalarda koroidal kalınlık değişiminiaraştırmak.Gereç ve Yöntem: Kesitsel, olgu-kontrollü, prospektifçalışma için HKM tanılı 33 hastanın 65 gözü ile sağlıklı 33bireyin 65 gözü çalışmaya dâhil edildi. Spektral DomainZeiss Cirrus cihazı ile her iki grup arasındaki retina sinirlifi (RNFL) kalınlığı, santral makula kalınlığı, makulahacmi, gangliyon hücre kalınlığı, subfoveal koroid kalınlığı(SKK), fovea 1 mm nazal koroid kalınlığı (NKK) ve fovea 1mm temporal koroid kalınlığı (TKK) karşılaştırıldı.Bulgular: HKM grubunda 33 hastanın 11’i kadın, 22’sierkek idi. Kontrol grubunda 33 hastanın 10’u kadın, 23’üerkek idi. HKM grubunun yaş ortalaması 41,90±14,6, kontrol grubunun yaş ortalaması 37,9±13,4 olarak saptandı.Koroid kalınlığını etkileyebilecek yaş, vücut kitle endeksi,sferik eşdeğer, aksiyel uzunluk ve göz içi basıncı değerleriarasında her 2 grup arasında anlamlı fark saptanmadı.SFKK, HKM grubunda 266,3±50,1 µm, kontrol grubunda273,6±56,8 µm olarak saptandı. NKK, HKM grubunda262±55,9 µm, kontrol grubunda 261,2±41,4 µm olaraksaptandı. TKK, HKM grubunda 270,5±58,5 µm, kontrolgrubunda 259,4±52,7 µm olarak saptandı. RNFL, makulakalınlığı, makula hacmi, SFKK, NKK, TKK değerlerindeher 2 grup arasında istatistiksel olarak fark saptanmadı.Sonuç: Diyastolik disfonksiyonu gelişmiş HKM’li hastalarda oküler kan akımının önemli bir bulgusu olan koroidkalınlığında değişim saptanmaması, diyastolik kalp disfonksiyonunda posterior siliyer arterlerde belirgin kanakım azalmasının olmadığını düşündürmektedir.

🔖

Cite This Article

BAYRAMOĞLU, S. E., SAYIN, N., ÖZBAY, S. (2022). Effect of Diastolic Heart Dysfunction Due to Hypertrophic Cardiomyopathy on Choroidal Thickness. İstanbul Kanuni Sultan Süleyman Tıp Dergisi, Cilt: 10 - Sayı: 3, 143–148. https://ajindex.com/articles/551062

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (9)

  1. Alm A, Bill A. Ocular and optic nerve blood flow at normal and increased intraocular pressures in monkeys (Macaca irus): a study with radioactively labelled microspheres including flow determinations in brain and some other tissues. Exp Eye Res. 1973;15(1):15-29.
  2. Gemenetzi M, De Salvo G, Lotery A. Central serous chorioretinopathy: an update on pathogenesis and treatment. Eye. 2010;24(12):1743.
  3. Hosoda Y, Uji A, Hangai M, Morooka S, Nishijima K, et al. Relationship between retinal lesions and inward choroidal bulging in Vogt-Koyanagi-Harada disease. Am J Ophthalmol. 2014;157(5):1056-63. e1
  4. Koizumi H, Yamagishi T, Yamazaki T, Kawasaki R, Kinoshita S. Subfoveal choroidal thickness in typical age-related macular degeneration and polypoidal choroidal vasculopathy. Graefes Arch Clin Exp Ophthalmol. 2011;249(8):1123-8.
  5. Tan K-A, Gupta P, Agarwal A, Chhablani J, Cheng CY, et al. State of science: choroidal thickness and systemic health. Surv Ophthalmol. 2016;61(5):566-81.
  6. Authors/Task Force m, Elliott PM, Anastasakis A, Borger MA, Borggrefe M, et al. 2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy: the Task Force for the Diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology (ESC). Eur Heart J. 2014;35(39):2733-79.
  7. Altinkaynak H, Kara N, Sayin N, Gunes H, Avsar S, et al. Subfoveal choroidal thickness in patients with chronic heart failure analyzed by spectral-domain optical coherence tomography. Curr Eye Res. 2014;39(11): 1123-8.
  8. Schiller NB, Shah PM, Crawford M, DeMaria A, Devereux R, et al. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms. J Am Soc Echocardiogr. 1989;2(5):358-67.
  9. Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, et al. Recommendations for chamber quantification: a report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a bran