Journals / İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi / 2017 / Cilt: 24 - Sayı: 2

Fluctuation of liver transaminases with gluten-free diet compliance of a patient with celiac disease and autoimmune hepatitis; a case report

Pages
210–213
Publication Date
2022-10-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Clinicians should consider that other autoimmune diseases may occur in the course celiac disease and gluten-free diet may improve also extra-intestinal manifestations of celiac disease.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Although the association of celiac disease with autoimmune hepatitis is well-known, the effect of gluten-free diet on autoimmune hepatitis progression is poorly deafined.
📊
Key Findings & Data:We described a patient with celiac disease coexisting with autoimmune hepatitis and effectiveness of gluten-free diet on both diseases.
💡
Conclusion & Impact:Clinicians should consider that other autoimmune diseases may occur in the course celiac disease and gluten-free diet may improve also extra-intestinal manifestations of celiac disease.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Although the association of celiac disease with autoimmune hepatitis is well-known, the effect of gluten-free diet on autoimmune hepatitis progression is poorly deafined. We described a patient with celiac disease coexisting with autoimmune hepatitis and effectiveness of gluten-free diet on both diseases. A young patient with eleveted serum liver transaminases was diagnosed as celiac disease and autoimmune hepatitis according to clinical, laboratory and pathological findings. Clinical complaints and laboratory findings of patients resolved exactly after glutenfree diet. However, liver transaminases eleveted and clinical manifestations re-emerged when he left the diet. Clinicians should consider that other autoimmune diseases may occur in the course celiac disease and gluten-free diet may improve also extra-intestinal manifestations of celiac disease.

🔖

Cite This Article

HARMANDAR, F., GÖRGÜLÜGİL, G. Z., DOLU, S., KOKER, G., GULENAY, S. A., UYAR, S., CEKİN, A. H. (2022). Fluctuation of liver transaminases with gluten-free diet compliance of a patient with celiac disease and autoimmune hepatitis; a case report. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, Cilt: 24 - Sayı: 2, 210–213. https://ajindex.com/articles/549628

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Leffler DA, Green PH, Fasano A. Extraintestinal manifestations of coeliac disease. Nat Rev Gastroenterol Hepatol 2015;12(10):561-71.
  2. Kahaly GJ, Schuppan D. Celiac disease and endocrine autoimmunity. Dig Dis 2015;33(2):155-61. Freeman HJ. Hepatic manifestations of celiac disease. Clin Exp Gastroenterol 2010;3:33-9.
  3. Seyhan M, Erdem T, Ertekin V, Selimoğlu MA. The mucocutaneous manifestations associated with celiac disease in childhood and adolescence. Pediatr Dermatol 2007;24(1):28-33.
  4. Xing Y, Morgan SL. Celiac disease and metabolic bone disease. J Clin Densitom 2013;16(4):439-44.
  5. Işikay S, Kocamaz H. The Neurologıcal face of Celiac disease. Arq Gastroenterol 2015;52(3):167-70.
  6. Bayar N, Çekin AH, Arslan Ş, Çağırcı G, Küçükseymen S, Çay S, et al. Assessment of Aortic Elasticity in Patients with Celiac Disease. Korean Circ J 2016;46(2):239-45. Pratt DS. Liver Chemistry and Function Tests. In: Feldman M, Friedman LS, Brandt LJ, editors. Sleisenger and Fordtran’s Gastrointestinal and Liver Disease. 10th ed. Philadelphia, USA: Saunders, Elisevier 2016.p.1243-53
  7. Karmen A, Wroblewski F, Ladue JS. Transaminase activity in human blood. J Clin İnvestI 1955;34(1):126-31. Manns MP1, Czaja AJ, Gorham JD, Krawitt EL, MieliVergani G, Vergani D, et al. Diagnosis and management of autoimmune hepatitis. Hepatology 2010;51(6):2193- 213. Hennes EM, Zeniya M, Czaja AJ, Parés A, Dalekos GN, Krawitt EL, et al. Simplified criteria for the diagnosis of autoimmune hepatitis. Hepatology 2008;48(1):169-76.
  8. Alvarez F, Berg PA, Bianchi FB, Bianchi L, Burroughs AK, Cancado EL, et al. International Autoimmune Hepatitis Group Report: Review of criteria for diagnosis of autoimmune hepatitis. J Hepatol 1999;31(5):929-38.
  9. Mirzaagha F, Azali SH, Islami F, Zamani F, Khalilipour E, Khatibian M, Eet al. Coeliac disease in autoimmune liver disease: a cross-sectional study and a systematic review. Dig Liver Dis 2010;42(9):620-3.
  10. Anania C, De Luca E, De Castro G, Chiesa C, Pacifico L. Liver involvement in pediatric celiac disease. World J Gastroenterol 2015;21;21(19):5813-22.
  11. Lo Iacono O, Petta S, Venezia G, Di Marco V, Tarantino G, Barbaria F, et al. Anti-tissue transglutaminase antibodies in patients with abnormal liver tests: is it always coeliac disease? Am J Gastroenterol 2005;100(11):2472-7.
  12. Hagander B, Berg NO, Brandt L, Nordén A, Sjölund K, Stenstam M. Hepatic injury in adult coeliac disease. Lancet 1977;2(8032):27-02.
  13. Newton KP, Singer SA. Celiac disease in children and adolescents: special