Journals / İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi / 1999 / Cilt: 6 - Sayı: 4

The relationship between the stage of gastric carcinoma, fibrinogen levels and platelet counts

Mide kanserlerinde hastalığın evresi ile fibrinojen ve platelet sayısı arasındaki ilişki

Pages
281–285
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Fibrinogen concentration was significantly higher in patients with gastric carcinoma than in age and sex matched control patients with benign disease (p

📌 3 Key Takeaways

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Objective & Hypothesis:A hypercoagulable state is well recognized in association with malignant tumors and results in a greatly increased risk of thromboembolic disease during surgery in these patients.
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Key Findings & Data:Fibrinogen concentration and platelet counts were examined in a consecutive group of 25 patients with gastric carcinoma.
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Conclusion & Impact:Fibrinogen concentration was significantly higher in patients with gastric carcinoma than in age and sex matched control patients with benign disease (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A hypercoagulable state is well recognized in association with malignant tumors and results in a greatly increased risk of thromboembolic disease during surgery in these patients. This study examines fibrinogen and platelet levels and attempts to correlate these with disease stage in patients with gastric carcinoma. Fibrinogen concentration and platelet counts were examined in a consecutive group of 25 patients with gastric carcinoma. All patients were staged according to UICC TNM classification. Fibrinogen concentration was significantly higher in patients with gastric carcinoma than in age and sex matched control patients with benign disease (p

Özet

Birçok tümörde koagülasyon sisteminde aktivasyon söz konusudur. Bu durum cerrahi esnasında tromboembolik komplikasyon riskinin artmasına neden olur. Prospektif olarak gerçekleştirilen bu klinik çalışmada 25 mide kanseri olgusu incelendi (Grup I). Kontrol grubu olarak kanser dışı olgulardan oluşan 25 olgu çalışmaya dahil edildi (Grup II), Tüm olgularda fibrinojen ve platelet düzeyleri incelendi ve TNM sınıflandırmasına göre tümörün evresi ile ilişkili olup olmadığı araştırıldı. Grup I'de fibrinojen düzeyi 534 mg/dL, Grup II'de 227 mg/dL (p0.05). Mide kanserli olgularda evre arttıkça fibrinojen ve platelet düzeylerinde buna paralel artışlar saptandı (p

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Cite This Article

KIRIMLIOĞLU, V., ARA, C., YILDIRIM, B., YILMAZ, S., ÇAĞLIKÜLEKÇİ, M., AKOĞLU, M., ERTAŞ, E. (2022). The relationship between the stage of gastric carcinoma, fibrinogen levels and platelet counts. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, Cilt: 6 - Sayı: 4, 281–285. https://ajindex.com/articles/549597

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