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Journals / İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi / 2000 / Cilt: 7 - Sayı: 2

Does inhaled corticosteroid use in asthma lead to ocular hypertension or open-angle glaucoma?

Astımda inhale kortikosteroid kullanımı göz içi basıncında yükselmeye veya açık açılı glaukoma yol açar mı?

Hakan GÜNEN
Cem EVEREKLİOĞLU
Mehmet BORAZAN
Selim DOĞANAY
Pages
105–108
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

High intra-ocular pressure was not detected in the control group (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In our study, we aimed to evaluate the effect of longterm low dose use of inhaled corticosteroids (CS) on ocular hypertension and open-angle glaucoma, Material and Methods: The study included 35 patients with asthma using inhaled CS in a dose less than 1000 mcg/day for longer than 5 years who never utilised other forms of CS.
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Key Findings & Data:Detailed eye examination and measurement of intra-ocular pressure of the patients and age matched control group (n=40) were performed by an ophtalmologist.
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Conclusion & Impact:High intra-ocular pressure was not detected in the control group (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: In our study, we aimed to evaluate the effect of longterm low dose use of inhaled corticosteroids (CS) on ocular hypertension and open-angle glaucoma, Material and Methods: The study included 35 patients with asthma using inhaled CS in a dose less than 1000 mcg/day for longer than 5 years who never utilised other forms of CS. Detailed eye examination and measurement of intra-ocular pressure of the patients and age matched control group (n=40) were performed by an ophtalmologist. Findings obtained were evaluated by comparing within the same group and between the groups separately for right and left eyes. Results: Regarding the mean intra-ocular pressure, there was not any statistically significant difference (p>0.05), between patients (right eye=14.2±3.2, left eye=14.3±3.1 mmHg) and control group (right eye=12.9±2.6, left eye=13.0±2.7 mmHg). However, in four asthmatic patients (11.4%), intra-ocular pressure was higher than 20 mmHg without open-angle glaucoma. High intra-ocular pressure was not detected in the control group (p

Özet

Amaç: Bu çalışmamızda, astımlı hastalarda uzun süreli düşük doz infiale kortikosteroid (KS) kullanımının, göz içi basıncı ve açık açılı glaukom üzerine etkisini araştırdık. Materyal ve Metot: Çalışmaya 5 yıldan fazla ve günde 1000 mcg/gün'den az dozda inhale KS kullanan ve diğer KS formlarını hiç kullanmamış 35 astımlı hasta alındı. Hasta ve yaşça benzer kontrol gruplarının (n=40) detaylı göz muayeneleri ve göz içi basıncı ölçümleri göz uzmanı tarafından yapıldı. Elde edilen bulgular gruplar içinde, gruplar arasında ve sağ ve sol gözlerde ayrı ayrı karşılaştırıldı. Bulgular: Ortalama göz içi basıncında hasta grubu (sağ göz =14.2±3.2, sol göz =14.3±3.1 mmHg) ve kontrol grubu (sağ göz =12.9±2.6, sol göz =13.0±2.7 mmHg) arasında fark saptanmadı (p>0,05). Bununla birlikte, hasta grubunda dört hastada (%11.4) göz içi basıncı, 20 mmHg'nin üzerinde idi ve açık açılı glaukom yoktu. Kontrol grubunda yüksek göz içi basıncı saptanmadı (p

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Cite This Article

GÜNEN, H., EVEREKLİOĞLU, C., BORAZAN, M., DOĞANAY, S. (2022). Does inhaled corticosteroid use in asthma lead to ocular hypertension or open-angle glaucoma?. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, Cilt: 7 - Sayı: 2, 105–108. https://ajindex.com/articles/549559

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