Journals / İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi / 2000 / Cilt: 7 - Sayı: 1

The comparison of the efficacy of empirical antibiotic regimens in febrile neutropenic patients

Febril nötropenili hastalarda ampirik antibiyotik rejimlerinin etkinliklerinin karşılaştırılması

Pages
19–23
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There was no significant difference in the efficacy and toxicity of antibiotics between the four different regimens (p>0.05).

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: To compare of the efficacy of empirical antibiotic regimens in febrile neutropenic patients in in Adult Hematology Clinic of Turgut Ozal Medical Center.
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Key Findings & Data:Material and methods: Four different antibiotic regimens Ceftazidime+Amikacin (n=19), Imipenem + Amikacin (n=14), Cefepime + Amikacin (n=20) and Sulbactam / Cefoperozone + Amikacin (n=20) were assessed as initial empirical therapy in febrile neutropenic patients, Results: Seventy-three febrile neutropenic episodes in 43 patients were evaluated.
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Conclusion & Impact:There was no significant difference in the efficacy and toxicity of antibiotics between the four different regimens (p>0.05).
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: To compare of the efficacy of empirical antibiotic regimens in febrile neutropenic patients in in Adult Hematology Clinic of Turgut Ozal Medical Center. Material and methods: Four different antibiotic regimens Ceftazidime+Amikacin (n=19), Imipenem + Amikacin (n=14), Cefepime + Amikacin (n=20) and Sulbactam / Cefoperozone + Amikacin (n=20) were assessed as initial empirical therapy in febrile neutropenic patients, Results: Seventy-three febrile neutropenic episodes in 43 patients were evaluated. There was no significant difference in the efficacy and toxicity of antibiotics between the four different regimens (p>0.05).

Özet

Amaç: Turgut Özal Tıp Merkezi erişkin Hematoloji kliniğindeki febril nötropenik hastalarda ampirik tedavi rejimlerinin etkinliklerinin karşılaştırılması. Materyal ve metot: Dört farklı antibiyotik rejimi, Seftazidim+Amikasin (n=19), İmipenem+ Amikasin (n=14), Sefepim+Amikasin (n=20), Sulbaktam/Sefoperazon+Amikasin (n=20) karşılaştırıldı. Kırk üç hastada gelişen toplam 73 febril nötropenik atak değerlendirildi. Bulgular: Dört farklı antibiyotik rejimi alan gruplar arasında etkinlik ve toksite açısından fark yoktu (p>0.05). Sonuç: Her dört rejim de toksisite ve etkinlik açısından febril nötropenik hastalarda başlangıç tedavisinde kullanılabileceği görüşüne varıldı.

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Cite This Article

SARI, R., AYDOĞDU, İ., ŞAVLI, H., SEVİNÇ, A., BAYRAKTAR, M. (2022). The comparison of the efficacy of empirical antibiotic regimens in febrile neutropenic patients. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, Cilt: 7 - Sayı: 1, 19–23. https://ajindex.com/articles/549521

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