Journals / İnönü Üniversitesi Tıp Fakültesi Dergisi / 2002 / Cilt: 9 - Sayı: 4

The values of QT and QT c dispersion in children with congenital ventricular septal defect

Konjenital VSD'li çocuklarda QT ve QT c dispersiyon değerleri

Pages
241–243
Publication Date
2022-10-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion the data of this study suggest that the patients with VSD appear to have repolarization abnormalities, reflected by an increase in QT and QTc dispersion.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The QT interval dispersion has long been known to be a marker of dispersion of ventricular repolarisation or electrical instability.
📊
Key Findings & Data:We examined 21 patients (mean age;6±2 years, 9M, 12F) with VSD and 26 age matched healthy subjects as the control group (mean age;9± 3 years, 14M, 12F).
💡
Conclusion & Impact:In conclusion the data of this study suggest that the patients with VSD appear to have repolarization abnormalities, reflected by an increase in QT and QTc dispersion.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The QT interval dispersion has long been known to be a marker of dispersion of ventricular repolarisation or electrical instability. Additionally, it has previously been shown that congenital ventricular septal defects (VSD) occasionally induce a QRS axis shift. There is no knowledge about QT and QTc dispersion indicating inhomogenous myocardial repolarization in the patients with VSD. In this study, we examined the values of dispersion of ventricular repolarization in the patients with VSD. We examined 21 patients (mean age;6±2 years, 9M, 12F) with VSD and 26 age matched healthy subjects as the control group (mean age;9± 3 years, 14M, 12F). We found QTd and QTc-d intervals of 54.2 ± 12.2 ms, 72,4 ± 9.2 ms in the patients withVSD, where the values for control group were 45.1 ± 11.3ms and 61.5 ± 6.7ms respectively (for all, P< 0.05). Important increase in QT and QTc dispersion indicating inhomogenous myocardial repolarization were noted in patients with VSD. In conclusion the data of this study suggest that the patients with VSD appear to have repolarization abnormalities, reflected by an increase in QT and QTc dispersion. This finding may be important in the explanation of ventricular repolarization abnormalities in patients with VSD.

Özet

QT interval dispersiyonunun, ventriküler repolarizasyon dispersiyonu veya elektriksel instabilitenin bir göstergesi olduğu uzun zamandır bilinmektedir. Ayrıca, konjenital ventriküler septal defektlerin (VSD) bazen QRS aks değişikliğine neden olduğu daha önceden belirlenmiştir. VSD'si olan hastalarda ventriküler repolarizasyon heterojenitesini gösteren QT ve QTc dispersiyonu hakkında hiçbir bilgi yoktur. Bu çalışmada, konjenital VSD olanlar çocuklarda ventriküler repolarizasyon dispersiyon değerlerini araştırdık. Çalışma VSD'si olan 21 hastayı (ortalama yaş;6± 2yıl, 12 E, 9 K) ve kontrol grubu olarak 26 sağlıklı çocuğu (ortalama yaş;9± 3yıl, 14 E, 12 K) içeriyordu. VSD'si olan hastalarda QT ve QTc dispersiyon değerleri sırasıyla 54.2+/-12.2, 72.48+/- 9.2 ms iken kontrol grubunda bu değerler sırasıyla 45.1+/- 11.3ms, 61.5+/-6.7 ms olduğunu bulduk (tümü için p < 0.05). VSD'si olan hastalarda homojen olmayan miyokardiyal repolarizasyonu gösteren QT ve QTc dispersiyon değerlerinde önemli artışlar olduğu kaydedildi. Sonuç olarak, bu çalışma konjenital VSD'i olan hastaların QT ve QTc dispersiyonunun artması olarak yansıyan repolarizasyon anormalliklerine sahip olduğunu ortaya çıkarmıştır. QT ve QTc dispersiyonunun artması VSD''i olan hastalarda ventriküler repolarizasyon anormalliklerinin açıklanmasında önemli olabilir.

🔖

Cite This Article

KORKUT, M., KOŞAR, F., SEZGİN, A., PAÇ, A. (2022). The values of QT and QT c dispersion in children with congenital ventricular septal defect. İnönü Üniversitesi Tıp Fakültesi Dergisi, Cilt: 9 - Sayı: 4, 241–243. https://ajindex.com/articles/548974

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (17)

  1. Lepeschkin E, Surawics B. The measurement of the QT interval or" the electrocardiogram. Circulation 1952;6:378-88
  2. Day CP, McComb JM, Campbell RVV. QT dispersion: an mdicafion of arrhythmia risk¬in patients with long QT intervals. Br Heart J 1990;63:342-4
  3. Starters DJ, Malik M, Ward DE, Camm Aj. QT dispersion: problems of methodology and clinical significance. J Cardiovasc Elcctrophysioi 1994;5:672-85
  4. Higharn PD, Campbell RV. QT dispersion. Br Heart J 1994;71:508-10
  5. Swcnsson RE. QRS axis in isolated peri membranous ventricular septal defect. J Electrocardiol 2001;34(3):205
  6. HE Tutar et al. QRS axis in isolated perimembranous ventricular septal defect and influences of morphological factors on QRS axis, j Kloctrocardiol 2001;34(3):197-203. 7. jcrvcll A, Lange. Nielsen F. Congenital deaf-mutism, functional heart disease with prolongation of the QT interval, and sudden death. Am Heart J 1957; 54:59-68
  7. Romano C, Gemmc G, pongıglıone R: Antmie cardiache rare dell' eta'pediatnea. Clinica Pediat 1963;45:656-683
  8. Schwartz PJ: Idiopathic long QT syndrome. Progress and question. Am Heart J 1985;109:399-411
  9. Ward OC: A new familial cardiac syndrome in children. J Irish Med Assoc 1964;54:103-106
  10. Schwartz PJ, Wolf S: QT interval prolongation as predictor oi sudden death in patients with mycardial infarction. Circulation 1978;57:1074-77 12. Dc Ambriogg L, Negroni MS, Monza i, Bertoni T, Schwartz PJ. Dispersion of ventricular repolarisation in the long QT syndrome. AmJ Cardiol 1991;68:614-20
  11. Kuo CS, Munakata K, Rcddy CP, Surawicz B. Characteristics and possible mechanism of ventricular arrhythmia dependent on the dispersion ot action potential durations. Circulation 1983;67:1356-67
  12. Puddy PM, Bourassa MG; Prediction of sudden death from QTc interval prolongation in patients with chronic ischemic heart disease. J Electrocardiol 1986;19:203-212
  13. B.izett HC An analysis of the time-relations of electrocardiogram. Heart 1920;7:353-70
  14. Surawicz B, r-lnocbel SB. Long QT: good, bad or indifferent?.) Am Coll Cardiol 1984;4:398-413
  15. Morgan roth h J. QTc interval prolongation: is it beneficial or harmful? Am J Cardiol 1993;72:1B-59B
  16. Mcrx W, Yoon MS, i lan J. The role of local disparity in conduction and recovery time on ventricular vulnerability to fibrillation. Am Heart J 1977;94:603-10
  17. Abildskov JA, Burgess MJ, Urie PM, lux RL, Wyatr RK The unidentified content of" the electrocardiogram. Circ Res 1977;40:3-7.