Journals / İnönü Üniversitesi Tıp Fakültesi Dergisi / 2007 / Cilt: 14 - Sayı: 3

CRP ile metabolik sendrom arasındaki ilişki

The association between C-reactive protein and metabolic syndrome components

Pages
145–148
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

In patients, we found a poor but significant relationship between fasting glucose levels and CRP (P=0.0001, r=0.3) and between HOMA-IR values and CRP (P=0.007, r=0.29).Conclusion: We concluded that CRP may have an important role in the diagnosis and follow-up of metabolic syndrome.

📌 3 Key Takeaways

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Objective & Hypothesis:Background: Insulin resistance is associated with metabolic syndrome and is a risk factor for cardiovascular disease.
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Key Findings & Data:C-reactive protein (CRP) is an inflammatory marker which is demonstrated as a strong predictor of future cardiovascular events.Material Method: In this study, sixty-three patients who were diagnosed with metabolic syndrome and twenty healthy controls were recruited.
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Conclusion & Impact:In patients, we found a poor but significant relationship between fasting glucose levels and CRP (P=0.0001, r=0.3) and between HOMA-IR values and CRP (P=0.007, r=0.29).Conclusion: We concluded that CRP may have an important role in the diagnosis and follow-up of metabolic syndrome.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background: Insulin resistance is associated with metabolic syndrome and is a risk factor for cardiovascular disease. C-reactive protein (CRP) is an inflammatory marker which is demonstrated as a strong predictor of future cardiovascular events.Material Method: In this study, sixty-three patients who were diagnosed with metabolic syndrome and twenty healthy controls were recruited. Fasting blood glucose, insulin and CRP levels were measured. Homeostasis Model Assessment (HOMA-IR) formula is used to evaluate insulin resistance. We investigated the relationship between insulin resistance and CRP levels and whether CRP is a metabolic syndrome criterion or not.Results: There were statistically significant differences between patients with metabolic syndrome and controls in terms of waist circumference, fasting glucose, insulin and CRP levels. In patients, we found a poor but significant relationship between fasting glucose levels and CRP (P=0.0001, r=0.3) and between HOMA-IR values and CRP (P=0.007, r=0.29).Conclusion: We concluded that CRP may have an important role in the diagnosis and follow-up of metabolic syndrome.

Özet

Giriş: İnsülin direnci metabolik sendrom ile ilişkilidir ve kardiyovasküler hastalıklar için risk faktörüdür. C-Reaktif protein (CRP) gelecekteki kardiyovasküler hastalıkların habercisi olan bir proinflamatuar belirteçdir. Biz bu çalışmada insülin direnci ile CRP düzeylerinin ilişkisini ve CRP’nin metabolik sendromda kriter olup olmayacağını araştırdık.Gereç ve Yöntem: Bu çalışmaya metabolik sendrom tanısı almış 63 hasta ile 20 sağlıklı kontrol grubu dahil edildi. Açlık kan glukoz seviyeleri, insülin ve CRP düzeyleri ölçüldü. İnsülin dirençleri (Homeostasis Model Assessment=HOMA-IR) formülü kullanılarak değerlendirildi.Bulgular: Metabolik sendromlu hasta grubu ile kontrol grubu arasında bel çevresi, açlık glukozu, insülin ve CRP değerleri arasında istatistiksel anlamlı farklılıklar vardı. Hasta grubunda açlık glukoz düzeyleri ve CRP arasında (P=0,0001, r=0,3) ve HOMA-IR ile CRP arasında (P=0,007, r=0,29) zayıf fakat anlamlı bir ilişki vardı.Sonuç: CRP’nin metabolik sendromun tanı ve takibinde önemli bir parametre olduğu sonucuna vardık.

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Cite This Article

KURAL, A., OMMA, A., YİĞİT, N., SEVAL, H., KOLDAŞ, M. (2022). CRP ile metabolik sendrom arasındaki ilişki. İnönü Üniversitesi Tıp Fakültesi Dergisi, Cilt: 14 - Sayı: 3, 145–148. https://ajindex.com/articles/548687

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