Journals / İnönü Üniversitesi Tıp Fakültesi Dergisi / 2009 / Cilt: 16 - Sayı: 3

Term and preterm children with cerebral palsy: Etiology, clinic and magnetic resonance imaging findings

Term ve preterm serebral palsili çocuklarda etiyoloji, klinik ve manyetik rezonans görüntüleme bulguları

Pages
169–172
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Cranial MR images of preterm patients revealed that PVL and CC pathology were the most common central nervous system lesions.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Cerebral palsy (CP) is a frequent neurologic disease of term and preterm neonates.
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Key Findings & Data:Thirty six preterm and 66 term CP patients aged between 6 months-16 years were evaluated in this study and were compared according to their etiology, clinical manifestation and cerebral Magnetic Resonance Imagıng (MRI) findings statistically.
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Conclusion & Impact:Cranial MR images of preterm patients revealed that PVL and CC pathology were the most common central nervous system lesions.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: Cerebral palsy (CP) is a frequent neurologic disease of term and preterm neonates. The disorder has various causes and the etiology, clinical manifestations and radiological screening findings are different in term and preterms. Thirty six preterm and 66 term CP patients aged between 6 months-16 years were evaluated in this study and were compared according to their etiology, clinical manifestation and cerebral Magnetic Resonance Imagıng (MRI) findings statistically. Material and Method: In this study, 36 preterm and 66 term CP patients, aged between 6 months-16 years were evaluated retrospectively.These patients were living in Malatya city and its neighborhood. Results: Twenty six of term (%39.4) patients and 20 (%55.5) of preterm patients were the first child. The most common CP etiology was perinatal asphyxia (%57.5) of term and (%41.6) of preterm. CP. The frequency of spastic tetraplegia and diplegia was respectively %45, %19.6 and %47, %38.8 in term and preterm CP. Fifty persent of term and %50 of preterm patients had microcephaly and %31.8 term and %47.2 preterm children had strabismus. Most of the CPs had cranial lesions on MRI. Periventricular leukomalacia (PVL) was seen in (%44) term and (%88) preterm patients. Corpus callosum (CC) pathology was seen in %36.4 of term and %69.4 preterm patients. Conclusion: According to our findings, perinatal asphyxia was the most common CP reason and spastic tetraplegia was the most common CP type. Cranial MR images of preterm patients revealed that PVL and CC pathology were the most common central nervous system lesions.

Özet

Amaç: Serebral palsi hem term hem preterm doğmuş çocuklarda sık görülen nörolojik bir bozukluktur. Bozukluğun preterm ve term çocuklar arasındaki etiyolojik nedenleri, klinik ve radyolojik görüntüleme bulguları farklıdır. Bu çalışmada yaşları 6 ay-16 yaş arasında değişen 36 preterm ve 66 term Serebral Palsi’li (SP) 102 çocuk,etiyoloji, klinik ve manyetik rezonans görüntüleme (MRG) bulguları yönünden istatistiksel olarak araştırıldı. Materyal ve Metot: Bu çalışmada bir yıllık bir sürede Malatya ili ve çevresindeki, yaşları 6 ay-16 yaş arasındadeğişen 36 preterm ve 66 term (SP)’li çocuk retrospektif olarak değerlendirildi. Bulgular: Term serebral palsi (TSP)’lerin 26’sı (%39.4) ve preterm serebral palsi (PSP)’lerin 20’si (%55.5) ilk çocuk idi . En sık görülen SP nedeni, TSP’lerin %57.5’inde ve PSP’lerin %41.6’sında perinatal asfiksi idi. Spastik tetrapleji ve dipleji, TSP ve PSP’lerde sırasıyla %45, %19.6 ve %47, %38.8 oranında idi. Hem TSP hemde PSP’lerde sırayla %50’sinde mikrosefali tesbit edildi. TSP’lerde %31.8, PSP’lerde %47.2 şaşılık görüldü. Kraniyal MRG’de, SP’lerin büyük çoğunluğunda patolojik değişiklik saptandı. Bu değişiklikler, TSP’lerin %44’ünde ve PSP’lerin %88’inde periventriküler lökomalazi (PVL), TSP’lerin %36.4’ünde, PSP’lerin %69.4’inde korpus kallozum (CC) patolojisi idi. Sonuç: Çalışmamızda TSP ve PSP’lilerin etiyolojisinde en sık neden perinatal asfiksi, en fazla bulunan SP tipi de spastik tetrapleji olarak belirlendi. PSP’lilerde MRG’de, PVL ve korpus kallozum patolojisinin daha fazla olduğu saptandı.

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Cite This Article

ASLAN, M., ADIN, S., DOĞAN, M., YAKINCI, C., ALKAN, A. (2022). Term and preterm children with cerebral palsy: Etiology, clinic and magnetic resonance imaging findings. İnönü Üniversitesi Tıp Fakültesi Dergisi, Cilt: 16 - Sayı: 3, 169–172. https://ajindex.com/articles/548552

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