Journals / İnönü Üniversitesi Tıp Fakültesi Dergisi / 2012 / Cilt: 19 - Sayı: 3

The clara cell

Clara hücresi

Pages
192–198
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The aim of this review was to give information about morphological and function features of the Clara cells.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Clara cells firstly identified as a distinct cell type by Kolliker in 1881 are non-ciliated secretory cells located in the small airways.
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Key Findings & Data:These cells can be easily identified by their distinct dome-shaped morphology and numerous secretory granules among the other epithelial cells.
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Conclusion & Impact:The aim of this review was to give information about morphological and function features of the Clara cells.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Clara cells firstly identified as a distinct cell type by Kolliker in 1881 are non-ciliated secretory cells located in the small airways. These cells can be easily identified by their distinct dome-shaped morphology and numerous secretory granules among the other epithelial cells. The distribution of Clara cells throughout the respiratory system is in a species-specific manner. These cells have several lung protective functions. Clara cells, basically function in lung homeostasis, play roles in xenobiotic metabolism and immune system regulation. In humans, many forms of lung cancer originate from Clara cells. The aim of this review was to give information about morphological and function features of the Clara cells.

Özet

İlk kez 1881 yılında Kolliker tarafından farklı bir hücre tipi olarak tanımlanan Clara hücreleri küçük hava yollarında bulunan, sil içermeyen, sekretuar hücrelerdir. Diğer epitel hücreleri arasında kubbe biçimli morfolojileri ve bol sekretuar granülleri ile kolay tanınırlar. Clara hücrelerinin respiratuar sistemdeki dağılımı türe özgü farklılıklar gösterir. Bu hücreler akciğeri koruyucu çeşitli fonksiyonlara sahiptir. Temel olarak akciğer homeostazının sağlanmasında görev alan Clara hücreleri, ksenobiyotik metabolizmasında ve immun sistemin regülasyonununda da rol alırlar. İnsanlarda akciğer kanserinin pek çok formu Clara hücrelerinden kaynaklanmaktadır. Bu derlemenin amacı; Clara hücrelerinin morfolojik ve fonksiyonal özellikleri hakkında bilgi vermektir.

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Cite This Article

EŞREFOĞLU, M., ELBE, H. (2022). The clara cell. İnönü Üniversitesi Tıp Fakültesi Dergisi, Cilt: 19 - Sayı: 3, 192–198. https://ajindex.com/articles/548426

References (1)

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