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Journals / İnfeksiyon Dergisi / 1997 / Cilt: 11 - Sayı: 1

Activity of imipenem and meropenem on aminoglycoside-resistant and extended spectrum beta lactamase-positive gram-negative bacteria

Aminoglikozitlere dirençli ve geniş spektrumlu beta laktamaz-pozitif gram- negatif bakterilerde meropenem ve imipenem etkinliği

Gül DURMAZ
Ünver YILDIZ
Yurdanur AKGÜN
Aydın AYDINLI
Pages
19–22
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There was no strain resistant to meropenem.

📌 3 Key Takeaways

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Objective & Hypothesis:Suspectibilities of 22 Gram-negative bacteria to imipenem and meropenem which produce extended spectrum beta-lactamase (ESBL) and resistant to amikacin, tobramycin, gentamicin and netilmicin were investigated.
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Key Findings & Data:Of them 12 were Klebsiella pneumoniae. four 'Enterobacter aeroaenes. three Escherichia coli. one Klebsiella oxvtoca. one Enterobacter sakazakii and one Enterobacter cloacae.
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Conclusion & Impact:There was no strain resistant to meropenem.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Suspectibilities of 22 Gram-negative bacteria to imipenem and meropenem which produce extended spectrum beta-lactamase (ESBL) and resistant to amikacin, tobramycin, gentamicin and netilmicin were investigated. Of them 12 were Klebsiella pneumoniae. four 'Enterobacter aeroaenes. three Escherichia coli. one Klebsiella oxvtoca. one Enterobacter sakazakii and one Enterobacter cloacae. Double disk synergy method was used for detection of ESBL, and suspectibility to antimicrobial agents was evaluated by using disk diffusion method. One strain of K. oneumoniae was found resistant to imipenem. There was no strain resistant to meropenem.

Özet

ESBL (extended spectrum beta lactamase) salgılayan amikasin, tobramisin, gentamisin ve netilmisine dirençli infeksiyon etkeni 12'si Klebsiella pneumoniae. dördü Enterobacter aeroaenes. üçü Escherichia coli. biri Klebsiella oxvtoca.biri Enterobacter sakazakii ve biri Enterobacter cloacae susu olmak üzere toplam 22 Gram-negatif bakterinin imipenem ve meropeneme duyarlılıkları araştırıldı. ESBL varlığını saptamada çift diskli sinerji, antimikrobik ilaçlara duyarlılığı saptamada ise disk difüzyon yöntemi kullanıldı. Bir K. pneumoniae susu imipeneme dirençli bulundu. Suşların hiçbirinde meropenem direncine rastlanmadı.

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Cite This Article

DURMAZ, G., YILDIZ, Ü., AKGÜN, Y., AYDINLI, A. (2022). Activity of imipenem and meropenem on aminoglycoside-resistant and extended spectrum beta lactamase-positive gram-negative bacteria. İnfeksiyon Dergisi, Cilt: 11 - Sayı: 1, 19–22. https://ajindex.com/articles/547154

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