Journals / İnfeksiyon Dergisi / 1997 / Cilt: 11 - Sayı: 1

The effect of topical clindamycin treatment on slime production, crystal violet reaction and development of antibiotic resistance in coagulase-negative staphylococci

Topikal klindamisin kullanımının koagülaz-negatif stafilokoklarda slime yapımı, kristal viyole reaksiyonu ve direnç gelişimine etkisi

Pages
33–36
Publication Date
2022-10-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

A correlation was found between topical clindamycin therapy, slime production and crystal violet reaction (p < 0.001 and p < 0.01).

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Antibiotic resistance, slime production and crystal violet reactions in coagulase-negative staphylococci were investigated in 20 patients with acne vulgaris who had received topical clindamycin therapy for a duration of eight weeks.
📊
Key Findings & Data:Pretreatment prevalence of resistance to 11 different antibiotics-not including imipenem, vancomycin and rifampin was between 5 and 70 %.
💡
Conclusion & Impact:A correlation was found between topical clindamycin therapy, slime production and crystal violet reaction (p < 0.001 and p < 0.01).
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Antibiotic resistance, slime production and crystal violet reactions in coagulase-negative staphylococci were investigated in 20 patients with acne vulgaris who had received topical clindamycin therapy for a duration of eight weeks. Pretreatment prevalence of resistance to 11 different antibiotics-not including imipenem, vancomycin and rifampin was between 5 and 70 %. There was an increase of 10-35 % in the prevalence of resistance to antibiotics other than vancomycin after the treatment. All strains were resistant to erythromycin, while 90 % of strains were resistant to clindamycin after treatment. A correlation was found between topical clindamycin therapy, slime production and crystal violet reaction (p < 0.001 and p < 0.01).

Özet

Akne vulgarisli hastalarda, topikal klindamisin kullanımının deri florasıdaki koagüJazzûügatif, stafilokoklarda (KNS) antibiyotik direnci, slime yapımı ve kristalj^hjBâl^iiyoMMiaL4K^B^, etkisi araştırılmıştır. Yirmi hastaya sekiz hafta süreyle topikal klindamisin tedavisi uygulanmıştır. Tedavi öncesinde imipenem, vankomisin ve rifampin dışında kullanılan tüm antibiyotiklere % 5-70 oranında direnç saptanmıştır. Tedavi sonrasında ise vankomisin dışında kullanılan tüm antibiyotiklere karşı % 10-35 arasında direnç artışı görülmüştür. Tedavi sonrası KNS'ların tümünde eritromisine, % 90'ında ise klindamisine direnç saptanmıştır. Topikal klindamisin kullanımı ile slime yapımı ve KVR pozitifliği arasında ilişki bulunmuştur (p < 0.001, p< 0.01).

🔖

Cite This Article

DURMAZ, G., AKGÜN, Y., AYDINLI, A., ÖZKAN, M. (2022). The effect of topical clindamycin treatment on slime production, crystal violet reaction and development of antibiotic resistance in coagulase-negative staphylococci. İnfeksiyon Dergisi, Cilt: 11 - Sayı: 1, 33–36. https://ajindex.com/articles/547109

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...