Journals / İnfeksiyon Dergisi / 1999 / Cilt: 13 - Sayı: 2

The seroprevalance of Epstein-Barr virus infection: A field study

Epstein-Barr virüs infeksiyonunun seroprevalansı: Bir alan çalışması

Pages
275–280
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Early antigen-IgG positive 13 subjects' new blood samples were tested for EA-lgG six months later and only three were found to be still positive.

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of this study was determine the seroprevalance of Epstein-Barr Virus (EBV).
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Key Findings & Data:Randomization method was used to choose 180 healthy 0-30 year-old people to be included in the study.
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Conclusion & Impact:Early antigen-IgG positive 13 subjects' new blood samples were tested for EA-lgG six months later and only three were found to be still positive.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The aim of this study was determine the seroprevalance of Epstein-Barr Virus (EBV). Randomization method was used to choose 180 healthy 0-30 year-old people to be included in the study. Indirect immunoflorescence method was used to determine the specific antibodies of EBV in blood samples. The seropositivity of viral capsid antigen-IgG (VCA-IgG) antibodies, which represent the exposure to EBV, for the total population and for the first four years were 84.4.% and 67.9%, respectively. There was a significant increase in EBV infection which is directly proportional to age. Viral capsid antigen-IgG positive samples were tested for EA- IgG which represent reactivation or chronic infection, and 7.2% of them were found to be positive. Early antigen-IgG positive 13 subjects' new blood samples were tested for EA-lgG six months later and only three were found to be still positive.

Özet

Bu çalışmada Epstein-Barr Virüsü (EBV)'nün seroprevalansının belirlenmesi amaçlanmıştır. Rastgele örneklem tablosu kullanılarak, 180 sağlıklı 0-30 yaşlarındaki kişiler çalışmaya seçilmiştir. Kan örneklerinde EBV' ye özgü antikorların belirlenmesinde immünfloresan yöntemi kullanılmıştır. Epstein-Barr Virüs ile karşılaşmanın belirleyicisi olan viral kapsit antijenine (VCA) karşı IgG antikorlarının seropozitifliği tüm toplum için %84.4 iken ilk dört yaş için de %67.9 bulunmuştur; infeksiyonunda yaş ile doğru orantıda anlamlı bir artış vardır. Viral kapsit antijeni-lgG pozitif olan örneklerde reaktivasyon veya kronik infeksiyonu gösteren erken antijene karşı IgG tipinde antikorlar (EA-lgG) araştırılmış ve %7.2'sinde olumlu bulunmuştur. Erken antijen-lgG pozitif olan 13 kişinin altı ay sonra yeni kan örneklerinde EA-lgG tekrar araştırılmış ve sadece üçünde pozitifliğin sürdüğü saptanmıştır.

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Cite This Article

AYDEMİR, Ş., ERENSOY, S. (2022). The seroprevalance of Epstein-Barr virus infection: A field study. İnfeksiyon Dergisi, Cilt: 13 - Sayı: 2, 275–280. https://ajindex.com/articles/546930

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