Ochrobactrum anthropi bacteremia developed after cholangiopancreatography

Since there was no clinical response to empirical ceftriaxone therapy, it was switched to meropenem, which was found effective by VITEK antibiotic susceptibility detection

📌 3 Key Takeaways

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Objective & Hypothesis:Ochrobactrum anthropi (formerly Achromobacter spp.) is an aerobic, motile, oxidase positive and lactose negative gram negative bacillus which is widely distributed in the environment and water sources.

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Key Findings & Data:A 89-year old female patient presented with high fever one day after ERCP performed due to klatskin tumour.

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Conclusion & Impact:Since there was no clinical response to empirical ceftriaxone therapy, it was switched to meropenem, which was found effective by VITEK antibiotic susceptibility detection

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Çapraz enfeksiyon · Kadın · Gram-negatif bakteriyel enfeksiyonlar

Abstract

Ochrobactrum anthropi (formerly Achromobacter spp.) is an aerobic, motile, oxidase positive and lactose negative gram negative bacillus which is widely distributed in the environment and water sources. In recent publications, O.anthropi has an increasing importance as a nosocomial infection agent. The aim of this report was to present a case of O.anthropi bacteremia developed after endoscopic retrograde oholangiopancreatography (ERCP). A 89-year old female patient presented with high fever one day after ERCP performed due to klatskin tumour. O.anthropi had been grown in blood culture (BacT/ALERT 3D, bioMerieux, Durham, USA), and the isolate was identified by automatized system (VITEK, bioMerieux, Marcy I'Etoile, France). Since there was no clinical response to empirical ceftriaxone therapy, it was switched to meropenem, which was found effective by VITEK antibiotic susceptibility detection

Özet

Çevresel ve su kaynaklı bir gram negatif basil olan Ochrobactrum anthropi (önceden Achromobacter spp.), aerop, hareketli, oksidaz pozitif, laktoz negatif bir bakteridir. Son yıllardaki yayınlarda nozokomiyal enfeksiyon etkeni olarak O.anthropi'ye dikkat çekilmektedir. Bu raporda, endoskopik retrograt kolanjiopankreatografi (ERKP) sonrası gelişen bir O.anthropi bakteriyemi olgusu sunulmuştur. Klatzkin tümörü nedeniyle ERKP yapılan 89 yaşındaki kadın hastanın ateşinin yükselmesi üzerine alınan kan kültüründe (BacT/ALERT 3D, bioMerieux, Durham, USA) O.anthropi üremesi saptanmıştır. Bakterinin tanımlanması ve antibiyotik duyarlılığı otomatize sistemle (VITEK, bioMerieux, Marcy I'Etoile, France) gerçekleştirilmiştir. Ampirik olarak başlanan seftriakson tedavisine klinik yanıt alınamaması ve bakterinin duyarlı bulunması nedeniyle, tedavi meropeneme değiştirilmiş (3x1 gr/gün, 10 gün) ve hasta başarıyla tedavi edilmiştir. Sonuç olarak, nadir de olsa, ERKP sonrası bakteriyemi olgularında O.anthropi gibi olağan dışı mikroorganizmaların etken olarak karşımıza çıkabileceği akılda tutulmalıdır.

Keywords

Çapraz enfeksiyon Kadın Gram-negatif bakteriyel enfeksiyonlar Mikrobiyal duyarlılık testleri Ochrobactrum anthropi Tienamisinler Yaşlı 80 ve üzeri Anti-bakteriyel ajanlar Bakteriyemi Cross Infection Female Gram-Negative Bacterial Infections Microbial Sensitivity Tests Thienamycins Aged 80 and over Anti-Bacterial Agents Bacteremia

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Cite This Article

SİPAHİ, O. R., ÇALIK, Ş., MAZHAROĞULLARI, K., AYDEMİR, Ş., YAMAZHAN, T., TEKEŞİN, O. (2007). Ochrobactrum anthropi bacteremia developed after cholangiopancreatography. Mikrobiyoloji Bülteni, Cilt: 41 - Sayı: 3, 469–472. https://ajindex.com/articles/295160

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