Journals / İnfeksiyon Dergisi / 2003 / Cilt: 17 - Sayı: 4

Oxidative stress in measles

Kızamıkta oksidatif stres

Pages
381–383
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It is concluded that oxidative stress increases in measles and antioxidant agents can be beneficial in the treatment.

📌 3 Key Takeaways

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Objective & Hypothesis:Oxygen radicals are key molecules in the pathogenesis of various infectious diseases.
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Key Findings & Data:To investigate whether oxidative stress increases in measles or not, plasma malondialdehyde (MDA) levels, serum carbonyl levels and plasma total sulphydryl levels were measured in 25 measles patients and 25 healthy controls by using spectrophotometry.
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Conclusion & Impact:It is concluded that oxidative stress increases in measles and antioxidant agents can be beneficial in the treatment.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Oxygen radicals are key molecules in the pathogenesis of various infectious diseases. To investigate whether oxidative stress increases in measles or not, plasma malondialdehyde (MDA) levels, serum carbonyl levels and plasma total sulphydryl levels were measured in 25 measles patients and 25 healthy controls by using spectrophotometry. Plasma MDA and serum carbonyl levels in patients with measles were detected higher than those in the control group. Plasma sulphydryl levels were found to be lower in the patient group when compared with the control group. It is concluded that oxidative stress increases in measles and antioxidant agents can be beneficial in the treatment.

Özet

Oksijen radikalleri birçok infeksiyon hastalığının patogenezinde anahtar moleküllerdir. Kızamıkta oksidatif stres varlığını araştırmak amacıyla, 25 kızamık hastası ve 25 sağlıklı kontrolda plazma malondialdehit (MDA), serum karbonil ve plazma total sülfidril düzeylerinin spektrofotometrı' ile ölçümü yapıldı. Plazma MDA ve serum karbonil düzeyleri hasta grubunda kontrol grubuna göre daha yüksek saptandı. Plazma sülfidril düzeyleri ise hasta grubunda kontrol grubuna göre düşük bulundu. Kızamıkta oksidatif stresin arttığı ve tedavide anti-oksidan ajanların yararlı olabileceği görüşüne varıldı.

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Cite This Article

ERBAY, A., ERBAY, A. R., BAYKAM, N., DOKUZOĞUZ, B., EREN, Ş. (2022). Oxidative stress in measles. İnfeksiyon Dergisi, Cilt: 17 - Sayı: 4, 381–383. https://ajindex.com/articles/546644

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