AI Summary & Key Takeaways
AI InsightThe PCT levels of early syphilis were found statististically higher than healthy blood donors (p
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Abstract
The aim of this study was to determine the levels of procalcitonin (PCT) and C-reactive protein (CRP) in cases with early syphilis diagnosis by clinical findings and laboratory results and to compare the two indicators by determining their diagnostic performance. Twenty-nine patients (13 male, 16 female, aged 18-59) with early syphilis were included in this study and 30 patients withbacteremia as well as 30 healthy blood donors as control groups. Procalcitonin levels in the collected blood samples were measured . by monoclonal immunoluminometric method and CRP levels were measured by immunoturbidometric method. The mean and levels (minimum and maximum) of PCT were found as 0.80 (0.55-1.68), 7.5 (0.68-35.4), 0.39 (0.15-1.25) ng/ml for the groups of early syphilis, bacteremia and healthy blood donors, respectively. The mean and levels (minumum-maximum) of CRP were found as 0.79 (0.25-3.30), 12 (2.7-44.5), 0.64 (0.25-3.25) mg/dl, respectively, for the same groups. The mean and levels of PCT were found as 0.75 (0.61-1.09) and 0.82 (0.55-1.68) for primary (n: 9) and secondary syphilis (n: 20), respectively. The mean and levels of CRP were found as 1 (0.3-2.9), 0.69 (0.3-3.3), respectively, for the same groups. The PCT levels of early syphilis were found statististically higher than healthy blood donors (p
Özet
Bu çalışmanın amacı, klinik bulgular ve laboratuvar verileri ile erken sitiliz tanısı konulmuş olgularda, serum prokalsitonin (PCT) ve C-reaktif protein (CRP) düzeylerini belirlemek ve her iki belirtecin tanısal değerini saptayarak karşılaştırmalarını yapmaktır. Çalışmaya 18-59 yaş arası 13'ü erkek, 16'sı kadın 29 erken sifiliz olgusu ve ayrıca kontrol grubu olarak bakteremili ve sağlıklı kan vericisi olarak 30'ar olgu alınmıştır. Serumda PCT düzeyini saptamak için monoklonal immunoluminometrik, CRP düzeyini saptamak için ise immunoturbidimetrik yöntem kullanılmıştır. Prokalsitonin serum düzeyleri ortalama (minimum-maksimum) olarak erken sifilizli olgular, bakteremili ve sağlıklı kan vericilerinde sırasıyla 0.80 (0.55-1.68), 7.5 (0.68-35.4), 0.39 (0.15-1.25) ng/ml olarak belirlenirken, CRP düzeylerinin ortalaması ise aynı gruplar için sırasıyla 0.79 (0.25-3.30), 12 (2.7-44.5), 0.64 (0.25-3.25) mg/dl olarak belirlenmiştir. Prokalsitonin düzeyi erken sifilizli olgulardan primer dönem olgularda (dokuz olgu) 0.75 (0.61-1.09), sekonder dönem olgularda ise 0.82 (0.55-1.68) olarak belirlenirken; CRP, sırayla bir (0.3-2.9), 0.69 (0.3-3.3) olarak saptanmıştır. PCT düzeyi, erken sifilizli olguların, sağlıklı kontrol grubundan istatistiksel olarak yüksek (p