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Journals / International Journal of Secondary Metabolite / 2018 / Cilt: 5 - Sayı: 4

Evaluation of Antioxidant, Antimicrobial and Antimutagenic Activity with Irritation Effects of Ceramium rubrum (Red Algae) Extract

Nefise Ülkü KARABAY YAVAŞOĞLU
Adem GÜNER
Pages
279–287
Publication Date
2022-10-19
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, extracts of the algae did not show any mutagenicity or irritation effect even at the highest concentration.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:This study was conducted to evaluate antioxidant, antimutagenic and antimicrobial activities as well as irritation/toxicity efficacy of n-hexane, chloroform and methanol extracts of the red algae Ceramium rubrum C.
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Key Findings & Data:All extracts exerted moderate antimicrobial activity against tested microorganisms as 64–256 μg/mL.
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Conclusion & Impact:However, extracts of the algae did not show any mutagenicity or irritation effect even at the highest concentration.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Red algae · Antioxidant · Antimicrobial

Abstract

This study was conducted to evaluate antioxidant, antimutagenic and antimicrobial activities as well as irritation/toxicity efficacy of n-hexane, chloroform and methanol extracts of the red algae Ceramium rubrum C. Agardh (1881). While spectrophotometric methods were used for the determination of total phenol and flavonoid content, antioxidant activity was evaluated by DPPH assay. Antimicrobial and antimutagenic efficacy of extracts were determined by MIC method and Ames test, respectively. Also, HET-CAM test was used for irritation/toxicity of extracts. While methanol extract was found to have higher total flavonoid and phenolic contents than the other extracts and hexane showed higher antioxidant activity than other extracts. All extracts exerted moderate antimicrobial activity against tested microorganisms as 64–256 μg/mL. However, extracts of the algae did not show any mutagenicity or irritation effect even at the highest concentration.

Özet

This study was conducted to evaluate antioxidant, antimutagenic and antimicrobial activities as well as irritation/toxicity efficacy of n-hexane, chloroform and methanol extracts of the red algae Ceramium rubrum C. Agardh (1881). While spectrophotometric methods were used for the determination of total phenol and flavonoid content, antioxidant activity was evaluated by DPPH assay. Antimicrobial and antimutagenic efficacy of extracts were determined by MIC method and Ames test, respectively. Also, HET-CAM test was used for irritation/toxicity of extracts. While methanol extract was found to have higher total flavonoid and phenolic contents than the other extracts and hexane showed higher antioxidant activity than other extracts. All extracts exerted moderate antimicrobial activity against tested microorganisms as 64–256 μg/mL. However, extracts of the algae did not show any mutagenicity or irritation effect even at the highest concentration.

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Cite This Article

YAVAŞOĞLU, N. Ü. K., GÜNER, A. (2022). Evaluation of Antioxidant, Antimicrobial and Antimutagenic Activity with Irritation Effects of Ceramium rubrum (Red Algae) Extract. International Journal of Secondary Metabolite, Cilt: 5 - Sayı: 4, 279–287. https://ajindex.com/articles/541692

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