Journals / Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2003 / Cilt: 43 - Sayı: 3

Evaluation of oral glucose tolerance test in nonalcoholic fatty liver disease

Nonalkolik yağlı karaciğer hastalığında oral glukoz tolerans testinin değerlendirilmesi

Pages
149–152
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As a conclusion, diabetes must be searched in every case with nonalcoholic fatty liver disease with OGTT if it is indicated.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Nonalcoholic fatty liver disease consists of a variety of hepatic abnormalities, ranging from basic hepatosteatosis to advanced cirrhosis.
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Key Findings & Data:It is closely related to type 2 diabetes mellitus, obesity and hyperlipidemia.
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Conclusion & Impact:As a conclusion, diabetes must be searched in every case with nonalcoholic fatty liver disease with OGTT if it is indicated.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Nonalcoholic fatty liver disease consists of a variety of hepatic abnormalities, ranging from basic hepatosteatosis to advanced cirrhosis. It is closely related to type 2 diabetes mellitus, obesity and hyperlipidemia. In order to determine the relation between diabetes and hepatosteatosis, 41 patients, whose random liver ultrasound evaluations had revealed hepatosteatosis, were included to our study to perform oral glucose tolerance test (OGTT). They had no. other causes of fatty liver other than nonalcoholic fatty-liver disease. After OGTT, we found that 1 patient had diabetes, 5 patients had impaired glucose tolerance and 1 patient had impaired fasting glucose. If we sum up, we revealed 7 patients (17%) with abnormal glucose metabolism out of 41 who did not have any previous diabetic problems. As a conclusion, diabetes must be searched in every case with nonalcoholic fatty liver disease with OGTT if it is indicated.

Özet

Nonalkolik yağlı karaciğer hastalığı, basit hepatosteatozdan siroza kadar değişen karaciğer bozukluklarını kapsayan bir durumdur. Tip 2 diyabet, obezite ve hiperlipidemi ile yakın ilişkilidir. Diyabet ve hepatosteatoz ilişkisini araştırmak amacıyla, rastlantısal olarak karaciğer ultrasonografisinde hepatosteatoz saptanan 41 hastaya, yağlı karaciğere sebep olabilecek diğer sebepler ekarte edildikten sonra, oral glukoz tolerans testi (OGTT) yapıldı. Yapılan OGTT sonrası, 1 hastada diabetes mellitus, 5 hastada bozulmuş glukoz toleransı ve 1 hastada da bozulmuş açlık glukozu tespit edildi. Sonuç olarak daha önce diyabet ile ilgili bir rahatsızlığı olmaya toplam 7 olguda (%17) glukoz metabolizna bozukluğu saptadık. Bu sonuçlara göre, nonalkolik yağlı karaciğer hastalığı tespit edilen her olguda diyabet araştırılmalıdır. Gerektiğinde bu hastalarda OGTT yapılmasını önermekteyiz.

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Cite This Article

GÜMÜŞ, M., TEOMETE, M., BAŞAR, M., BİLGİ, M., GARİP, T., DEMİRTUNÇ, R. (2022). Evaluation of oral glucose tolerance test in nonalcoholic fatty liver disease. Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 43 - Sayı: 3, 149–152. https://ajindex.com/articles/535740

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