Journals / Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2003 / Cilt: 43 - Sayı: 4

The comparison of calculated values and direct measurement for ionized calcium

İyonize kalsiyum için direkt ölçüm ve hesaplanan değerlerin karşılaştırılması

Pages
230–234
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

For this reason, elimination of these factors as much as possible gives the closest result to the real va-lue when calcium is calculated using the formula.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Calcium, which is the most common cation in human body, is necessary for many important physiological functions.
📊
Key Findings & Data:Calcium is found in mainly 3 forms which are free, protein bounded and complex.
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Conclusion & Impact:For this reason, elimination of these factors as much as possible gives the closest result to the real va-lue when calcium is calculated using the formula.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Calcium, which is the most common cation in human body, is necessary for many important physiological functions. Calcium is found in mainly 3 forms which are free, protein bounded and complex. The ionized form can be measured directly with the ion selective electrode and can also be calculated by using several formulas. Changes in several factors such as the albumin level, pH, anions and drugs limit the efficient usage of the formulas. For this reason, elimination of these factors as much as possible gives the closest result to the real va-lue when calcium is calculated using the formula.

Özet

Vücudumuzun en yaygın katyonu olan kalsiyum, pek çok önemli fizyolojik fonksiyonlar için gereklidir Kalsiyum; serbest, proteinlere bağlı ve kompleks olmak üzere başlıca 3 formda bulunur. İyonize form, iyon selektif elektrot ile direkt olarak ölçülebildiği gibi çeşitli formüller kullanılarak da hesaplanabilir. Albumin düzeyi, pH, anyonlar, ilaçlar gibi çeşitli faktörlerdeki değişiklikler formüllerin etkin bir şekilde kullanımını sınırlarlar. Bu sebeple, bu faktörlerin mümkün olduğunca elimine edilmesi formülden hareketle İyonize kalsiyumun hesaplandığı durumlarda ideale en yakın sonucu verir.

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Cite This Article

ATALAY, S., KURÇENLİ, S., YEKREK, M. M. (2022). The comparison of calculated values and direct measurement for ionized calcium. Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 43 - Sayı: 4, 230–234. https://ajindex.com/articles/535713

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References (16)

  1. Henry, j. B. Clinical Diagnosis and Management by Laboratory Methods, pp. 152-155, 1991
  2. Carl, A. B. Edward, R. A.: Tietz Textbook of Clinical Chemistry 1986; pp. 1887-1906
  3. Nordin, B. E. C, Need, A. G., Hartley, T. F. et al. Improved method for calculating calcium fractions in plasma: Reference values and effect of menopause. Clin. Chem 1989; 35:14-17
  4. Ashby, J. P. Wright, D. J., Rinsler, M. G. The adjusted serum calcium concept a reappraisal. Ann. Clin. Biochem 1986; 23:533-537
  5. Johnson, K. R., Mascall, G. C, Howarth, A. T. Differential laboratory diagnosis of hypercalcemia. Crit. Rev. Clin. Lab. Sci 1984; 21:51-97
  6. Gitelman, H. J.: An improved automated procedure for the determination of calcium in biological specimens. Anal. Biochem 1967; 18:521-531
  7. Sorva, A. Elfving, S. Pohja, P., Tilvis, R. S. Assesment of calca-emic status in geriatric hospital patients: Serum ionized calcium versus albumin-adjusted total calcium. Scand. J. Clin. Lab. Invest 1998; 48:489-494
  8. Thode, J., Bhatia, H. M., et al. Adjusted ionized calcium (at pH 7.4) and actual ionized calcium (at actual pH) in capillary blood compared for clinical evaluation of patients with disorders of calcium metabolism. Clin. Chem 1990; 36:541-544
  9. Zaloga, G. P., Wiliey, S., Tomasic, P., Chernow, B. Free fatty acid alter calcium binding: A cause for misinterpretation of serum calcium values and hypocalcemia in critical Mines. J. Clin. Endocrinol. Metab 1987; 64:1010-1014
  10. Kelly, P. M., Bending, M. R., Barron, J. L. Comparison of serum calcium fractions during hemodialysis and periotoneal dialysis. Ann. Clin. Biochem 1987; 24: 585-590
  11. Buckley, B. M. Russell, L. J.: The measurement of ionized calcium in blood plasma. Ann. Clin. Biochem 1988; 25:447-465
  12. Thode. J.: Ionized calcium and cyclic AMP in plasma and urine. Scand. J. Clin. Lab. Invest 1990; 50 (Suppl. 197):13-45
  13. Fleisher, M., Gladstone, M., Crystal, D., Schwartz, M, K.; Two whole-blood multi-analyfe analyzers with buit-in pH correction. Clin. Chem 1981:27:1264-1267
  14. Boink, A. B. T, Buckley, B. M., Christiansen, T. F.,etal. Recommendations on blood sampling transport and storage for the determination of the substance concentration of ionized calcium. International -Federation of Clinical Chemistry 1986, pp. 81-88
  15. Sachs, C, Thode, J.: Preanalytical errors in ionized calcium determinations in blood: International -Federation of Clinical Che-mistry, 1986, pp. 259-270
  16. Toffaletti, J.,