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Journals / Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2005 / Cilt: 45 - Sayı: 3

Effect of benzalkonium chloride containing intranasal sprays on muscocillary clearance and symptoms in perennial rhinitis

Perennial allerjik rinitte, benzalkonyum klorür içeren intranazal steroidli spreylerin mukosiliyer klirens ve semptomlar üzerine etkisi

Ömer BİLAÇ
Murat KARAMAN
Oğuz GÜÇLÜ
Burak ÜLKÜMEN
Tahir BÜLBÜL
Celil USLU
Pages
149–154
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In our study, we compare the effect of steroid containing intranasal sprays with/without benzalkonium chloride on mucociliary clearance and the clinic state.

📌 3 Key Takeaways

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Objective & Hypothesis:Effect of Benzalkonium Chloride Containing Intranasal Sprays on Mucociliary Clearance and Symptoms in Perennial Allergic Rhinitis Allergic rhinitis is an immunoglobulin-E mediated public health problem effecting 10 to 30% of adults and 40% of children and it occurs after early and late immu¬ne response.
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Key Findings & Data:Steroid containing intranasal sprays have been effectively used in allergic rhinitis.
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Conclusion & Impact:In our study, we compare the effect of steroid containing intranasal sprays with/without benzalkonium chloride on mucociliary clearance and the clinic state.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Effect of Benzalkonium Chloride Containing Intranasal Sprays on Mucociliary Clearance and Symptoms in Perennial Allergic Rhinitis Allergic rhinitis is an immunoglobulin-E mediated public health problem effecting 10 to 30% of adults and 40% of children and it occurs after early and late immu¬ne response. Steroid containing intranasal sprays have been effectively used in allergic rhinitis. Some of these sprays contain benzalkonium chloride as preservative. In our study, we compare the effect of steroid containing intranasal sprays with/without benzalkonium chloride on mucociliary clearance and the clinic state.

Özet

Allerjik rinit, birtakım alerjenlere karşı, immünoglobülin-E kontrolünde erken ve geç faz immün cevabı takiben oluşan, erişkinlerin %10-30'unu, çocukların ise %40'ını etkileyen ciddi bir halk sağlığı problemidir. Steroid içeren topikal intranazal spreyler allerjik rinit tedavisinde etkin olarak kullanılmaktadırlar. Bu spreylerin bir kısmında koruyucu madde olarak benzalkonyum klorür yer almaktadır. Biz çalışmamızda, hikâye ve laboratuvar testleri ışığında allerjik rinit tanısı konan hastalarda benzalkonyum içeren ve içermeyen steroidli intranazal sprey kullanımının mukosiliyer klirens ve klinik tablo üzerine etkisini karşılaştırdık.

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Cite This Article

BİLAÇ, Ö., KARAMAN, M., GÜÇLÜ, O., ÜLKÜMEN, B., BÜLBÜL, T., USLU, C. (2022). Effect of benzalkonium chloride containing intranasal sprays on muscocillary clearance and symptoms in perennial rhinitis. Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 45 - Sayı: 3, 149–154. https://ajindex.com/articles/535652

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